Motif | KLF14.H12CORE.1.P.C |
Gene (human) | KLF14 (GeneCards) |
Gene synonyms (human) | BTEB5 |
Gene (mouse) | Klf14 |
Gene synonyms (mouse) | |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | C |
Motif | KLF14.H12CORE.1.P.C |
Gene (human) | KLF14 (GeneCards) |
Gene synonyms (human) | BTEB5 |
Gene (mouse) | Klf14 |
Gene synonyms (mouse) | |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | C |
Motif length | 23 |
Consensus | vdGdRGGYGKRRvnvbRdvdRdv |
GC content | 67.61% |
Information content (bits; total / per base) | 12.108 / 0.526 |
Data sources | ChIP-Seq |
Aligned words | 998 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 1 (6) | 0.684 | 0.7 | 0.499 | 0.519 | 0.804 | 0.819 | 3.03 | 3.074 | 1.509 | 5.854 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.695 | 0.654 | 0.66 | 0.629 | 0.629 | 0.605 |
best | 0.885 | 0.824 | 0.841 | 0.783 | 0.776 | 0.729 | |
Methyl HT-SELEX, 1 experiments | median | 0.842 | 0.769 | 0.809 | 0.74 | 0.759 | 0.702 |
best | 0.842 | 0.769 | 0.809 | 0.74 | 0.759 | 0.702 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.547 | 0.539 | 0.512 | 0.517 | 0.499 | 0.508 |
best | 0.885 | 0.824 | 0.841 | 0.783 | 0.776 | 0.729 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 2 | 0.53 | 0.01 | 0.363 | 0.1 |
TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
TF class | C2H2 zinc finger factors {2.3} (TFClass) |
TF family | Three-zinc finger Kruppel-related {2.3.1} (TFClass) |
TF subfamily | Kr-like {2.3.1.2} (TFClass) |
TFClass ID | TFClass: 2.3.1.2.14 |
HGNC | HGNC:23025 |
MGI | MGI:3577024 |
EntrezGene (human) | GeneID:136259 (SSTAR profile) |
EntrezGene (mouse) | GeneID:619665 (SSTAR profile) |
UniProt ID (human) | KLF14_HUMAN |
UniProt ID (mouse) | KLF14_MOUSE |
UniProt AC (human) | Q8TD94 (TFClass) |
UniProt AC (mouse) | Q19A41 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 1 human, 0 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | KLF14.H12CORE.1.P.C.pcm |
PWM | KLF14.H12CORE.1.P.C.pwm |
PFM | KLF14.H12CORE.1.P.C.pfm |
Alignment | KLF14.H12CORE.1.P.C.words.tsv |
Threshold to P-value map | KLF14.H12CORE.1.P.C.thr |
Motif in other formats | |
JASPAR format | KLF14.H12CORE.1.P.C_jaspar_format.txt |
MEME format | KLF14.H12CORE.1.P.C_meme_format.meme |
Transfac format | KLF14.H12CORE.1.P.C_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 312.0 | 200.0 | 398.0 | 88.0 |
02 | 373.0 | 106.0 | 251.0 | 268.0 |
03 | 153.0 | 12.0 | 791.0 | 42.0 |
04 | 166.0 | 45.0 | 480.0 | 307.0 |
05 | 206.0 | 41.0 | 706.0 | 45.0 |
06 | 83.0 | 11.0 | 825.0 | 79.0 |
07 | 64.0 | 43.0 | 878.0 | 13.0 |
08 | 211.0 | 551.0 | 5.0 | 231.0 |
09 | 24.0 | 23.0 | 937.0 | 14.0 |
10 | 41.0 | 33.0 | 614.0 | 310.0 |
11 | 185.0 | 40.0 | 704.0 | 69.0 |
12 | 239.0 | 44.0 | 584.0 | 131.0 |
13 | 154.0 | 528.0 | 249.0 | 67.0 |
14 | 173.0 | 365.0 | 170.0 | 290.0 |
15 | 219.0 | 159.0 | 494.0 | 126.0 |
16 | 133.0 | 149.0 | 519.0 | 197.0 |
17 | 209.0 | 140.0 | 590.0 | 59.0 |
18 | 280.0 | 99.0 | 418.0 | 201.0 |
19 | 172.0 | 142.0 | 589.0 | 95.0 |
20 | 264.0 | 100.0 | 389.0 | 245.0 |
21 | 162.0 | 94.0 | 659.0 | 83.0 |
22 | 232.0 | 83.0 | 503.0 | 180.0 |
23 | 168.0 | 185.0 | 573.0 | 72.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.313 | 0.2 | 0.399 | 0.088 |
02 | 0.374 | 0.106 | 0.252 | 0.269 |
03 | 0.153 | 0.012 | 0.793 | 0.042 |
04 | 0.166 | 0.045 | 0.481 | 0.308 |
05 | 0.206 | 0.041 | 0.707 | 0.045 |
06 | 0.083 | 0.011 | 0.827 | 0.079 |
07 | 0.064 | 0.043 | 0.88 | 0.013 |
08 | 0.211 | 0.552 | 0.005 | 0.231 |
09 | 0.024 | 0.023 | 0.939 | 0.014 |
10 | 0.041 | 0.033 | 0.615 | 0.311 |
11 | 0.185 | 0.04 | 0.705 | 0.069 |
12 | 0.239 | 0.044 | 0.585 | 0.131 |
13 | 0.154 | 0.529 | 0.249 | 0.067 |
14 | 0.173 | 0.366 | 0.17 | 0.291 |
15 | 0.219 | 0.159 | 0.495 | 0.126 |
16 | 0.133 | 0.149 | 0.52 | 0.197 |
17 | 0.209 | 0.14 | 0.591 | 0.059 |
18 | 0.281 | 0.099 | 0.419 | 0.201 |
19 | 0.172 | 0.142 | 0.59 | 0.095 |
20 | 0.265 | 0.1 | 0.39 | 0.245 |
21 | 0.162 | 0.094 | 0.66 | 0.083 |
22 | 0.232 | 0.083 | 0.504 | 0.18 |
23 | 0.168 | 0.185 | 0.574 | 0.072 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.222 | -0.219 | 0.464 | -1.03 |
02 | 0.4 | -0.847 | 0.006 | 0.071 |
03 | -0.485 | -2.907 | 1.149 | -1.748 |
04 | -0.404 | -1.682 | 0.651 | 0.206 |
05 | -0.19 | -1.772 | 1.036 | -1.682 |
06 | -1.087 | -2.983 | 1.191 | -1.135 |
07 | -1.341 | -1.726 | 1.253 | -2.837 |
08 | -0.166 | 0.789 | -3.62 | -0.076 |
09 | -2.279 | -2.318 | 1.318 | -2.771 |
10 | -1.772 | -1.979 | 0.896 | 0.216 |
11 | -0.297 | -1.795 | 1.033 | -1.268 |
12 | -0.043 | -1.704 | 0.846 | -0.638 |
13 | -0.478 | 0.746 | -0.002 | -1.296 |
14 | -0.363 | 0.378 | -0.38 | 0.149 |
15 | -0.129 | -0.447 | 0.68 | -0.676 |
16 | -0.623 | -0.511 | 0.729 | -0.234 |
17 | -0.176 | -0.572 | 0.857 | -1.42 |
18 | 0.115 | -0.914 | 0.513 | -0.214 |
19 | -0.369 | -0.558 | 0.855 | -0.954 |
20 | 0.056 | -0.904 | 0.442 | -0.018 |
21 | -0.428 | -0.965 | 0.967 | -1.087 |
22 | -0.072 | -1.087 | 0.698 | -0.324 |
23 | -0.392 | -0.297 | 0.828 | -1.226 |
P-value | Threshold |
---|---|
0.001 | 4.25211 |
0.0005 | 5.14496 |
0.0001 | 7.02231 |