KLF13.H12RSNP.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF13.H12RSNP.0.PSM.A
Gene (human)	KLF13 (GeneCards)
Gene synonyms (human)	BTEB3, NSLP1
Gene (mouse)	Klf13
Gene synonyms (mouse)	Bteb3, Fklf2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	17
Consensus	nddRKGGGCGTGGYnnn
GC content	69.95%
Information content (bits; total / per base)	17.176 / 1.01
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	9951

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (13)	0.76	0.82	0.642	0.749	0.781	0.826	3.021	3.408	30.921	111.678

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.994	0.988	0.989	0.982	0.966	0.956
Overall, 6 experiments	best	0.996	0.992	0.996	0.992	0.992	0.987
Methyl HT-SELEX, 2 experiments	median	0.994	0.988	0.989	0.982	0.971	0.961
Methyl HT-SELEX, 2 experiments	best	0.994	0.989	0.99	0.983	0.975	0.965
Non-Methyl HT-SELEX, 4 experiments	median	0.881	0.87	0.809	0.81	0.76	0.766
Non-Methyl HT-SELEX, 4 experiments	best	0.996	0.992	0.996	0.992	0.992	0.987

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.982	0.701	0.935	0.534
batch 2	0.876	0.522	0.9	0.718

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.13
HGNC	HGNC:13672
MGI	MGI:1354948
EntrezGene (human)	GeneID:51621 (SSTAR profile)
EntrezGene (mouse)	GeneID:50794 (SSTAR profile)
UniProt ID (human)	KLF13_HUMAN
UniProt ID (mouse)	KLF13_MOUSE
UniProt AC (human)	Q9Y2Y9 (TFClass)
UniProt AC (mouse)	Q9JJZ6 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	KLF13.H12RSNP.0.PSM.A.pcm
PWM	KLF13.H12RSNP.0.PSM.A.pwm
PFM	KLF13.H12RSNP.0.PSM.A.pfm
Alignment	KLF13.H12RSNP.0.PSM.A.words.tsv
Threshold to P-value map	KLF13.H12RSNP.0.PSM.A.thr
Motif in other formats
JASPAR format	KLF13.H12RSNP.0.PSM.A_jaspar_format.txt
MEME format	KLF13.H12RSNP.0.PSM.A_meme_format.meme
Transfac format	KLF13.H12RSNP.0.PSM.A_transfac_format.txt
Homer format	KLF13.H12RSNP.0.PSM.A_homer_format_0.001.txt KLF13.H12RSNP.0.PSM.A_homer_format_0.0005.txt KLF13.H12RSNP.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2168.25	1579.25	3903.25	2300.25
02	2988.5	896.5	3946.5	2119.5
03	3451.0	814.0	4023.0	1663.0
04	2007.0	127.0	7346.0	471.0
05	818.0	26.0	6476.0	2631.0
06	607.0	6.0	9283.0	55.0
07	10.0	16.0	9913.0	12.0
08	18.0	3.0	9922.0	8.0
09	63.0	9719.0	29.0	140.0
10	11.0	3.0	9928.0	9.0
11	20.0	15.0	108.0	9808.0
12	74.0	14.0	9810.0	53.0
13	365.0	111.0	7903.0	1572.0
14	322.0	6912.0	712.0	2005.0
15	2508.0	1908.0	3431.0	2104.0
16	1953.75	1757.75	2609.75	3629.75
17	2057.5	1690.5	3392.5	2810.5

PFM

	A	C	G	T
01	0.218	0.159	0.392	0.231
02	0.3	0.09	0.397	0.213
03	0.347	0.082	0.404	0.167
04	0.202	0.013	0.738	0.047
05	0.082	0.003	0.651	0.264
06	0.061	0.001	0.933	0.006
07	0.001	0.002	0.996	0.001
08	0.002	0.0	0.997	0.001
09	0.006	0.977	0.003	0.014
10	0.001	0.0	0.998	0.001
11	0.002	0.002	0.011	0.986
12	0.007	0.001	0.986	0.005
13	0.037	0.011	0.794	0.158
14	0.032	0.695	0.072	0.201
15	0.252	0.192	0.345	0.211
16	0.196	0.177	0.262	0.365
17	0.207	0.17	0.341	0.282

PWM

	A	C	G	T
01	-0.137	-0.454	0.45	-0.078
02	0.183	-1.019	0.461	-0.16
03	0.327	-1.115	0.48	-0.402
04	-0.215	-2.958	1.082	-1.66
05	-1.11	-4.477	0.956	0.056
06	-1.408	-5.704	1.316	-3.772
07	-5.31	-4.913	1.382	-5.16
08	-4.809	-6.152	1.383	-5.488
09	-3.641	1.362	-4.376	-2.862
10	-5.232	-6.152	1.383	-5.395
11	-4.715	-4.969	-3.117	1.371
12	-3.485	-5.029	1.371	-3.807
13	-1.914	-3.09	1.155	-0.458
14	-2.038	1.021	-1.249	-0.216
15	0.008	-0.265	0.321	-0.167
16	-0.241	-0.347	0.048	0.377
17	-0.19	-0.386	0.31	0.122

Standard thresholds

P-value	Threshold
0.001	0.19096
0.0005	1.81526
0.0001	5.17416