KLF13.H12CORE.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF13.H12CORE.0.PSM.A
Gene (human)	KLF13 (GeneCards)
Gene synonyms (human)	BTEB3, NSLP1
Gene (mouse)	Klf13
Gene synonyms (mouse)	Bteb3, Fklf2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	15
Consensus	nddRKGGGCGTGGYn
GC content	72.14%
Information content (bits; total / per base)	16.72 / 1.115
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	9993

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (13)	0.763	0.824	0.642	0.756	0.77	0.824	2.967	3.367	30.721	111.0

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.994	0.987	0.99	0.983	0.972	0.962
Overall, 6 experiments	best	0.997	0.992	0.996	0.993	0.992	0.988
Methyl HT-SELEX, 2 experiments	median	0.994	0.987	0.99	0.983	0.976	0.966
Methyl HT-SELEX, 2 experiments	best	0.994	0.987	0.99	0.983	0.977	0.967
Non-Methyl HT-SELEX, 4 experiments	median	0.986	0.973	0.94	0.931	0.831	0.845
Non-Methyl HT-SELEX, 4 experiments	best	0.997	0.992	0.996	0.993	0.992	0.988

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.973	0.663	0.921	0.537
batch 2	0.867	0.492	0.886	0.718

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.13
HGNC	HGNC:13672
MGI	MGI:1354948
EntrezGene (human)	GeneID:51621 (SSTAR profile)
EntrezGene (mouse)	GeneID:50794 (SSTAR profile)
UniProt ID (human)	KLF13_HUMAN
UniProt ID (mouse)	KLF13_MOUSE
UniProt AC (human)	Q9Y2Y9 (TFClass)
UniProt AC (mouse)	Q9JJZ6 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	KLF13.H12CORE.0.PSM.A.pcm
PWM	KLF13.H12CORE.0.PSM.A.pwm
PFM	KLF13.H12CORE.0.PSM.A.pfm
Alignment	KLF13.H12CORE.0.PSM.A.words.tsv
Threshold to P-value map	KLF13.H12CORE.0.PSM.A.thr
Motif in other formats
JASPAR format	KLF13.H12CORE.0.PSM.A_jaspar_format.txt
MEME format	KLF13.H12CORE.0.PSM.A_meme_format.meme
Transfac format	KLF13.H12CORE.0.PSM.A_transfac_format.txt
Homer format	KLF13.H12CORE.0.PSM.A_homer_format_0.001.txt KLF13.H12CORE.0.PSM.A_homer_format_0.0005.txt KLF13.H12CORE.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2200.25	2134.25	3500.25	2158.25
02	2716.0	1365.0	3954.0	1958.0
03	3129.0	1518.0	3728.0	1618.0
04	2081.0	195.0	7139.0	578.0
05	815.0	20.0	5434.0	3724.0
06	373.0	4.0	9584.0	32.0
07	5.0	11.0	9973.0	4.0
08	5.0	2.0	9977.0	9.0
09	14.0	9923.0	5.0	51.0
10	7.0	1.0	9984.0	1.0
11	11.0	3.0	83.0	9896.0
12	97.0	15.0	9798.0	83.0
13	384.0	223.0	8102.0	1284.0
14	380.5	5275.5	808.5	3528.5
15	1890.75	2567.75	2810.75	2723.75

PFM

	A	C	G	T
01	0.22	0.214	0.35	0.216
02	0.272	0.137	0.396	0.196
03	0.313	0.152	0.373	0.162
04	0.208	0.02	0.714	0.058
05	0.082	0.002	0.544	0.373
06	0.037	0.0	0.959	0.003
07	0.001	0.001	0.998	0.0
08	0.001	0.0	0.998	0.001
09	0.001	0.993	0.001	0.005
10	0.001	0.0	0.999	0.0
11	0.001	0.0	0.008	0.99
12	0.01	0.002	0.98	0.008
13	0.038	0.022	0.811	0.128
14	0.038	0.528	0.081	0.353
15	0.189	0.257	0.281	0.273

PWM

	A	C	G	T
01	-0.127	-0.157	0.337	-0.146
02	0.083	-0.604	0.459	-0.243
03	0.225	-0.498	0.4	-0.434
04	-0.183	-2.54	1.049	-1.461
05	-1.118	-4.72	0.777	0.399
06	-1.897	-5.983	1.344	-4.289
07	-5.836	-5.236	1.384	-5.983
08	-5.836	-6.365	1.384	-5.399
09	-5.033	1.379	-5.836	-3.848
10	-5.594	-6.63	1.385	-6.63
11	-5.236	-6.156	-3.378	1.376
12	-3.226	-4.973	1.366	-3.378
13	-1.868	-2.407	1.176	-0.665
14	-1.877	0.747	-1.126	0.345
15	-0.278	0.027	0.118	0.086

Standard thresholds

P-value	Threshold
0.001	-0.14889
0.0005	1.60066
0.0001	5.11271