MotifKLF12.H12INVIVO.0.P.C
Gene (human)KLF12
(GeneCards)
Gene synonyms (human)AP2REP
Gene (mouse)Klf12
Gene synonyms (mouse)Ap2rep
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
C
Motif length20
ConsensusvdGGGCGKGGMvdRRvvbSR
GC content79.13%
Information content (bits; total / per base)16.853 / 0.843
Data sourcesChIP-Seq
Aligned words907

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (5) 0.83 0.842 0.708 0.723 0.858 0.874 3.964 4.054 113.237 131.886

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.647 0.611 0.603 0.58 0.561 0.554
best 0.895 0.84 0.857 0.801 0.777 0.739
Methyl HT-SELEX, 1 experiments median 0.895 0.84 0.857 0.801 0.777 0.739
best 0.895 0.84 0.857 0.801 0.777 0.739
Non-Methyl HT-SELEX, 3 experiments median 0.538 0.535 0.515 0.517 0.505 0.509
best 0.755 0.687 0.692 0.643 0.617 0.599

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.707 0.133 0.79 0.517
batch 2 0.635 0.089 0.339 0.187
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyThree-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamilyKr-like {2.3.1.2} (TFClass)
TFClass IDTFClass: 2.3.1.2.12
HGNCHGNC:6346
MGIMGI:1333796
EntrezGene (human)GeneID:11278
(SSTAR profile)
EntrezGene (mouse)GeneID:16597
(SSTAR profile)
UniProt ID (human)KLF12_HUMAN
UniProt ID (mouse)KLF12_MOUSE
UniProt AC (human)Q9Y4X4
(TFClass)
UniProt AC (mouse)O35738
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01274.0345.0240.048.0
02235.033.0458.0181.0
0390.02.0793.022.0
040.05.0900.02.0
052.05.0898.02.0
06148.0702.01.056.0
0746.04.0840.017.0
0825.025.0672.0185.0
09104.05.0782.016.0
1046.024.0823.014.0
11107.0707.045.048.0
12156.0379.0223.0149.0
13162.084.0413.0248.0
14117.057.0689.044.0
15107.098.0681.021.0
16178.0255.0400.074.0
17150.0187.0489.081.0
18106.0182.0492.0127.0
19120.0123.0573.091.0
20132.097.0623.055.0
PFM
ACGT
010.3020.380.2650.053
020.2590.0360.5050.2
030.0990.0020.8740.024
040.00.0060.9920.002
050.0020.0060.990.002
060.1630.7740.0010.062
070.0510.0040.9260.019
080.0280.0280.7410.204
090.1150.0060.8620.018
100.0510.0260.9070.015
110.1180.7790.050.053
120.1720.4180.2460.164
130.1790.0930.4550.273
140.1290.0630.760.049
150.1180.1080.7510.023
160.1960.2810.4410.082
170.1650.2060.5390.089
180.1170.2010.5420.14
190.1320.1360.6320.1
200.1460.1070.6870.061
PWM
ACGT
010.1880.4170.056-1.525
020.035-1.8850.699-0.223
03-0.913-4.1221.247-2.266
04-4.899-3.5291.373-4.122
05-4.122-3.5291.371-4.122
06-0.4231.125-4.437-1.376
07-1.566-3.691.304-2.503
08-2.147-2.1471.081-0.202
09-0.771-3.5291.233-2.558
10-1.566-2.1851.284-2.678
11-0.7431.132-1.588-1.525
12-0.3710.511-0.017-0.416
13-0.333-0.980.5960.089
14-0.655-1.3591.106-1.609
15-0.743-0.8291.095-2.309
16-0.240.1170.564-1.105
17-0.409-0.1910.765-1.016
18-0.752-0.2180.771-0.574
19-0.63-0.6050.923-0.902
20-0.536-0.8391.006-1.394
Standard thresholds
P-value Threshold
0.001 2.37936
0.0005 3.59456
0.0001 6.13746