MotifKLF12.H12CORE.1.PSM.A
Gene (human)KLF12
(GeneCards)
Gene synonyms (human)AP2REP
Gene (mouse)Klf12
Gene synonyms (mouse)Ap2rep
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length13
ConsensusdddGGGCGTGGYv
GC content70.36%
Information content (bits; total / per base)14.558 / 1.12
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9706

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (5) 0.811 0.83 0.69 0.713 0.793 0.811 2.755 2.814 96.387 122.444

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.804 0.804 0.734 0.735 0.646 0.657
best 0.997 0.995 0.995 0.992 0.977 0.972
Methyl HT-SELEX, 1 experiments median 0.997 0.995 0.995 0.992 0.977 0.972
best 0.997 0.995 0.995 0.992 0.977 0.972
Non-Methyl HT-SELEX, 3 experiments median 0.623 0.632 0.554 0.567 0.526 0.538
best 0.984 0.976 0.914 0.904 0.766 0.777

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.872 0.426 0.858 0.529
batch 2 0.802 0.428 0.731 0.524
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyThree-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamilyKr-like {2.3.1.2} (TFClass)
TFClass IDTFClass: 2.3.1.2.12
HGNCHGNC:6346
MGIMGI:1333796
EntrezGene (human)GeneID:11278
(SSTAR profile)
EntrezGene (mouse)GeneID:16597
(SSTAR profile)
UniProt ID (human)KLF12_HUMAN
UniProt ID (mouse)KLF12_MOUSE
UniProt AC (human)Q9Y4X4
(TFClass)
UniProt AC (mouse)O35738
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012089.01473.03774.02370.0
022836.75936.753542.752389.75
033395.0205.02101.04005.0
04466.065.08980.0195.0
0578.0189.09368.071.0
0652.06.09591.057.0
0751.09136.067.0452.0
0824.03.09678.01.0
09110.054.0222.09320.0
10199.070.09182.0255.0
11350.0197.08802.0357.0
12382.754071.751059.754191.75
131880.54135.51864.51825.5
PFM
ACGT
010.2150.1520.3890.244
020.2920.0970.3650.246
030.350.0210.2160.413
040.0480.0070.9250.02
050.0080.0190.9650.007
060.0050.0010.9880.006
070.0050.9410.0070.047
080.0020.00.9970.0
090.0110.0060.0230.96
100.0210.0070.9460.026
110.0360.020.9070.037
120.0390.420.1090.432
130.1940.4260.1920.188
PWM
ACGT
01-0.15-0.4990.441-0.024
020.156-0.950.378-0.015
030.336-2.461-0.1440.501
04-1.646-3.5861.308-2.51
05-3.409-2.5411.35-3.501
06-3.801-5.6791.374-3.713
07-3.8191.325-3.557-1.676
08-4.526-6.1281.383-6.603
09-3.074-3.765-2.3821.345
10-2.49-3.5141.33-2.245
11-1.931-2.51.288-1.911
12-1.8420.517-0.8270.546
13-0.2550.533-0.263-0.284
Standard thresholds
P-value Threshold
0.001 2.64886
0.0005 3.85156
0.0001 6.630455