| Motif | KLF11.H12RSNP.1.SM.B |
| Gene (human) | KLF11 (GeneCards) |
| Gene synonyms (human) | FKLF, TIEG2 |
| Gene (mouse) | Klf11 |
| Gene synonyms (mouse) | Tieg2b, Tieg3 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | KLF11.H12RSNP.1.SM.B |
| Gene (human) | KLF11 (GeneCards) |
| Gene synonyms (human) | FKLF, TIEG2 |
| Gene (mouse) | Klf11 |
| Gene synonyms (mouse) | Tieg2b, Tieg3 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 25 |
| Consensus | ndnRKGGGCGTGKvRKGGGSGKKKb |
| GC content | 73.22% |
| Information content (bits; total / per base) | 25.529 / 1.021 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 1718 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 2 (14) | 0.655 | 0.678 | 0.454 | 0.499 | 0.731 | 0.743 | 2.371 | 2.608 | 4.21 | 7.036 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.995 | 0.992 | 0.989 | 0.983 | 0.95 | 0.942 |
| best | 0.996 | 0.993 | 0.99 | 0.985 | 0.954 | 0.944 | |
| Methyl HT-SELEX, 1 experiments | median | 0.994 | 0.991 | 0.987 | 0.981 | 0.954 | 0.944 |
| best | 0.994 | 0.991 | 0.987 | 0.981 | 0.954 | 0.944 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.996 | 0.993 | 0.99 | 0.985 | 0.946 | 0.94 |
| best | 0.996 | 0.993 | 0.99 | 0.985 | 0.946 | 0.94 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.89 | 0.708 | 0.898 | 0.717 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | C2H2 zinc finger factors {2.3} (TFClass) |
| TF family | Three-zinc finger Kruppel-related {2.3.1} (TFClass) |
| TF subfamily | Kr-like {2.3.1.2} (TFClass) |
| TFClass ID | TFClass: 2.3.1.2.11 |
| HGNC | HGNC:11811 |
| MGI | MGI:2653368 |
| EntrezGene (human) | GeneID:8462 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:194655 (SSTAR profile) |
| UniProt ID (human) | KLF11_HUMAN |
| UniProt ID (mouse) | KLF11_MOUSE |
| UniProt AC (human) | O14901 (TFClass) |
| UniProt AC (mouse) | Q8K1S5 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 2 human, 0 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | KLF11.H12RSNP.1.SM.B.pcm |
| PWM | KLF11.H12RSNP.1.SM.B.pwm |
| PFM | KLF11.H12RSNP.1.SM.B.pfm |
| Alignment | KLF11.H12RSNP.1.SM.B.words.tsv |
| Threshold to P-value map | KLF11.H12RSNP.1.SM.B.thr |
| Motif in other formats | |
| JASPAR format | KLF11.H12RSNP.1.SM.B_jaspar_format.txt |
| MEME format | KLF11.H12RSNP.1.SM.B_meme_format.meme |
| Transfac format | KLF11.H12RSNP.1.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 417.0 | 313.0 | 642.0 | 346.0 |
| 02 | 460.5 | 194.5 | 705.5 | 357.5 |
| 03 | 474.0 | 302.0 | 565.0 | 377.0 |
| 04 | 318.0 | 58.0 | 1219.0 | 123.0 |
| 05 | 188.0 | 10.0 | 791.0 | 729.0 |
| 06 | 96.0 | 1.0 | 1620.0 | 1.0 |
| 07 | 0.0 | 0.0 | 1718.0 | 0.0 |
| 08 | 1.0 | 0.0 | 1717.0 | 0.0 |
| 09 | 26.0 | 1658.0 | 0.0 | 34.0 |
| 10 | 6.0 | 0.0 | 1710.0 | 2.0 |
| 11 | 7.0 | 2.0 | 82.0 | 1627.0 |
| 12 | 52.0 | 18.0 | 1573.0 | 75.0 |
| 13 | 185.0 | 29.0 | 1132.0 | 372.0 |
| 14 | 217.0 | 918.0 | 367.0 | 216.0 |
| 15 | 372.0 | 129.0 | 1074.0 | 143.0 |
| 16 | 201.0 | 15.0 | 675.0 | 827.0 |
| 17 | 120.0 | 2.0 | 1467.0 | 129.0 |
| 18 | 9.0 | 2.0 | 1697.0 | 10.0 |
| 19 | 6.0 | 5.0 | 1698.0 | 9.0 |
| 20 | 44.0 | 1236.0 | 360.0 | 78.0 |
| 21 | 20.0 | 314.0 | 1362.0 | 22.0 |
| 22 | 7.0 | 43.0 | 475.0 | 1193.0 |
| 23 | 89.0 | 33.0 | 1179.0 | 417.0 |
| 24 | 179.5 | 87.5 | 1094.5 | 356.5 |
| 25 | 191.0 | 526.0 | 628.0 | 373.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.243 | 0.182 | 0.374 | 0.201 |
| 02 | 0.268 | 0.113 | 0.411 | 0.208 |
| 03 | 0.276 | 0.176 | 0.329 | 0.219 |
| 04 | 0.185 | 0.034 | 0.71 | 0.072 |
| 05 | 0.109 | 0.006 | 0.46 | 0.424 |
| 06 | 0.056 | 0.001 | 0.943 | 0.001 |
| 07 | 0.0 | 0.0 | 1.0 | 0.0 |
| 08 | 0.001 | 0.0 | 0.999 | 0.0 |
| 09 | 0.015 | 0.965 | 0.0 | 0.02 |
| 10 | 0.003 | 0.0 | 0.995 | 0.001 |
| 11 | 0.004 | 0.001 | 0.048 | 0.947 |
| 12 | 0.03 | 0.01 | 0.916 | 0.044 |
| 13 | 0.108 | 0.017 | 0.659 | 0.217 |
| 14 | 0.126 | 0.534 | 0.214 | 0.126 |
| 15 | 0.217 | 0.075 | 0.625 | 0.083 |
| 16 | 0.117 | 0.009 | 0.393 | 0.481 |
| 17 | 0.07 | 0.001 | 0.854 | 0.075 |
| 18 | 0.005 | 0.001 | 0.988 | 0.006 |
| 19 | 0.003 | 0.003 | 0.988 | 0.005 |
| 20 | 0.026 | 0.719 | 0.21 | 0.045 |
| 21 | 0.012 | 0.183 | 0.793 | 0.013 |
| 22 | 0.004 | 0.025 | 0.276 | 0.694 |
| 23 | 0.052 | 0.019 | 0.686 | 0.243 |
| 24 | 0.104 | 0.051 | 0.637 | 0.208 |
| 25 | 0.111 | 0.306 | 0.366 | 0.217 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.029 | -0.315 | 0.401 | -0.215 |
| 02 | 0.069 | -0.787 | 0.495 | -0.183 |
| 03 | 0.098 | -0.35 | 0.273 | -0.13 |
| 04 | -0.299 | -1.975 | 1.04 | -1.24 |
| 05 | -0.821 | -3.594 | 0.609 | 0.527 |
| 06 | -1.483 | -5.015 | 1.324 | -5.015 |
| 07 | -5.445 | -5.445 | 1.383 | -5.445 |
| 08 | -5.015 | -5.445 | 1.382 | -5.445 |
| 09 | -2.74 | 1.348 | -5.445 | -2.487 |
| 10 | -4.005 | -5.445 | 1.378 | -4.716 |
| 11 | -3.885 | -4.716 | -1.638 | 1.329 |
| 12 | -2.081 | -3.078 | 1.295 | -1.725 |
| 13 | -0.837 | -2.637 | 0.966 | -0.143 |
| 14 | -0.679 | 0.757 | -0.157 | -0.683 |
| 15 | -0.143 | -1.193 | 0.914 | -1.091 |
| 16 | -0.754 | -3.242 | 0.451 | 0.653 |
| 17 | -1.264 | -4.716 | 1.225 | -1.193 |
| 18 | -3.682 | -4.716 | 1.371 | -3.594 |
| 19 | -4.005 | -4.141 | 1.371 | -3.682 |
| 20 | -2.241 | 1.054 | -0.176 | -1.687 |
| 21 | -2.982 | -0.312 | 1.151 | -2.895 |
| 22 | -3.885 | -2.263 | 0.1 | 1.019 |
| 23 | -1.558 | -2.516 | 1.007 | -0.029 |
| 24 | -0.866 | -1.574 | 0.933 | -0.185 |
| 25 | -0.805 | 0.202 | 0.379 | -0.14 |
| P-value | Threshold |
|---|---|
| 0.001 | -4.72749 |
| 0.0005 | -2.86944 |
| 0.0001 | 1.07316 |