KLF11.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF11.H12RSNP.0.P.B
Gene (human)	KLF11 (GeneCards)
Gene synonyms (human)	FKLF, TIEG2
Gene (mouse)	Klf11
Gene synonyms (mouse)	Tieg2b, Tieg3
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	vvRGGGGCGGGGM
GC content	85.51%
Information content (bits; total / per base)	16.283 / 1.253
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (14)	0.779	0.794	0.607	0.636	0.852	0.858	3.173	3.266	46.831	53.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.857	0.793	0.819	0.756	0.766	0.713
Overall, 2 experiments	best	0.872	0.813	0.832	0.772	0.772	0.723
Methyl HT-SELEX, 1 experiments	median	0.842	0.773	0.807	0.74	0.76	0.703
Methyl HT-SELEX, 1 experiments	best	0.842	0.773	0.807	0.74	0.76	0.703
Non-Methyl HT-SELEX, 1 experiments	median	0.872	0.813	0.832	0.772	0.772	0.723
Non-Methyl HT-SELEX, 1 experiments	best	0.872	0.813	0.832	0.772	0.772	0.723

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.69	0.324	0.814	0.532

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.11
HGNC	HGNC:11811
MGI	MGI:2653368
EntrezGene (human)	GeneID:8462 (SSTAR profile)
EntrezGene (mouse)	GeneID:194655 (SSTAR profile)
UniProt ID (human)	KLF11_HUMAN
UniProt ID (mouse)	KLF11_MOUSE
UniProt AC (human)	O14901 (TFClass)
UniProt AC (mouse)	Q8K1S5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	KLF11.H12RSNP.0.P.B.pcm
PWM	KLF11.H12RSNP.0.P.B.pwm
PFM	KLF11.H12RSNP.0.P.B.pfm
Alignment	KLF11.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	KLF11.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	KLF11.H12RSNP.0.P.B_jaspar_format.txt
MEME format	KLF11.H12RSNP.0.P.B_meme_format.meme
Transfac format	KLF11.H12RSNP.0.P.B_transfac_format.txt
Homer format	KLF11.H12RSNP.0.P.B_homer_format_0.001.txt KLF11.H12RSNP.0.P.B_homer_format_0.0005.txt KLF11.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	154.0	232.0	541.0	73.0
02	435.0	181.0	259.0	125.0
03	246.25	47.25	680.25	26.25
04	59.25	2.25	873.25	65.25
05	188.25	5.25	804.25	2.25
06	2.25	1.25	992.25	4.25
07	3.25	14.25	982.25	0.25
08	16.25	916.25	2.25	65.25
09	7.25	1.25	988.25	3.25
10	4.25	7.25	969.25	19.25
11	101.25	4.25	885.25	9.25
12	124.25	34.25	828.25	13.25
13	97.25	793.25	71.25	38.25

PFM

	A	C	G	T
01	0.154	0.232	0.541	0.073
02	0.435	0.181	0.259	0.125
03	0.246	0.047	0.68	0.026
04	0.059	0.002	0.873	0.065
05	0.188	0.005	0.804	0.002
06	0.002	0.001	0.992	0.004
07	0.003	0.014	0.982	0.0
08	0.016	0.916	0.002	0.065
09	0.007	0.001	0.988	0.003
10	0.004	0.007	0.969	0.019
11	0.101	0.004	0.885	0.009
12	0.124	0.034	0.828	0.013
13	0.097	0.793	0.071	0.038

PWM

	A	C	G	T
01	-0.48	-0.074	0.768	-1.215
02	0.551	-0.32	0.035	-0.686
03	-0.015	-1.637	0.997	-2.197
04	-1.418	-4.148	1.246	-1.324
05	-0.281	-3.586	1.164	-4.148
06	-4.148	-4.437	1.373	-3.74
07	-3.924	-2.757	1.363	-4.847
08	-2.639	1.294	-4.148	-1.324
09	-3.334	-4.437	1.369	-3.924
10	-3.74	-3.334	1.35	-2.485
11	-0.894	-3.74	1.259	-3.133
12	-0.692	-1.945	1.193	-2.822
13	-0.933	1.15	-1.238	-1.84

Standard thresholds

P-value	Threshold
0.001	2.04986
0.0005	3.36341
0.0001	6.10922