| Motif | KLF11.H12INVITRO.1.SM.B |
| Gene (human) | KLF11 (GeneCards) |
| Gene synonyms (human) | FKLF, TIEG2 |
| Gene (mouse) | Klf11 |
| Gene synonyms (mouse) | Tieg2b, Tieg3 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | KLF11.H12INVITRO.1.SM.B |
| Gene (human) | KLF11 (GeneCards) |
| Gene synonyms (human) | FKLF, TIEG2 |
| Gene (mouse) | Klf11 |
| Gene synonyms (mouse) | Tieg2b, Tieg3 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 23 |
| Consensus | nRKGGGCGTGKvRKGGGCGTGdb |
| GC content | 72.76% |
| Information content (bits; total / per base) | 26.567 / 1.155 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 264 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 2 (14) | 0.592 | 0.611 | 0.446 | 0.472 | 0.703 | 0.72 | 2.136 | 2.324 | 2.825 | 6.276 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.997 | 0.995 | 0.99 | 0.986 | 0.949 | 0.942 |
| best | 0.997 | 0.995 | 0.991 | 0.987 | 0.958 | 0.95 | |
| Methyl HT-SELEX, 1 experiments | median | 0.997 | 0.995 | 0.991 | 0.987 | 0.958 | 0.95 |
| best | 0.997 | 0.995 | 0.991 | 0.987 | 0.958 | 0.95 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.997 | 0.995 | 0.989 | 0.985 | 0.941 | 0.935 |
| best | 0.997 | 0.995 | 0.989 | 0.985 | 0.941 | 0.935 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.831 | 0.489 | 0.869 | 0.717 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | C2H2 zinc finger factors {2.3} (TFClass) |
| TF family | Three-zinc finger Kruppel-related {2.3.1} (TFClass) |
| TF subfamily | Kr-like {2.3.1.2} (TFClass) |
| TFClass ID | TFClass: 2.3.1.2.11 |
| HGNC | HGNC:11811 |
| MGI | MGI:2653368 |
| EntrezGene (human) | GeneID:8462 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:194655 (SSTAR profile) |
| UniProt ID (human) | KLF11_HUMAN |
| UniProt ID (mouse) | KLF11_MOUSE |
| UniProt AC (human) | O14901 (TFClass) |
| UniProt AC (mouse) | Q8K1S5 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 2 human, 0 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | KLF11.H12INVITRO.1.SM.B.pcm |
| PWM | KLF11.H12INVITRO.1.SM.B.pwm |
| PFM | KLF11.H12INVITRO.1.SM.B.pfm |
| Alignment | KLF11.H12INVITRO.1.SM.B.words.tsv |
| Threshold to P-value map | KLF11.H12INVITRO.1.SM.B.thr |
| Motif in other formats | |
| JASPAR format | KLF11.H12INVITRO.1.SM.B_jaspar_format.txt |
| MEME format | KLF11.H12INVITRO.1.SM.B_meme_format.meme |
| Transfac format | KLF11.H12INVITRO.1.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 58.0 | 45.0 | 88.0 | 73.0 |
| 02 | 74.25 | 13.25 | 150.25 | 26.25 |
| 03 | 55.0 | 1.0 | 101.0 | 107.0 |
| 04 | 40.0 | 0.0 | 224.0 | 0.0 |
| 05 | 0.0 | 0.0 | 264.0 | 0.0 |
| 06 | 0.0 | 0.0 | 264.0 | 0.0 |
| 07 | 1.0 | 263.0 | 0.0 | 0.0 |
| 08 | 0.0 | 0.0 | 264.0 | 0.0 |
| 09 | 0.0 | 0.0 | 1.0 | 263.0 |
| 10 | 5.0 | 0.0 | 257.0 | 2.0 |
| 11 | 36.0 | 3.0 | 143.0 | 82.0 |
| 12 | 43.0 | 136.0 | 59.0 | 26.0 |
| 13 | 81.0 | 12.0 | 153.0 | 18.0 |
| 14 | 42.0 | 0.0 | 100.0 | 122.0 |
| 15 | 40.0 | 0.0 | 218.0 | 6.0 |
| 16 | 0.0 | 1.0 | 263.0 | 0.0 |
| 17 | 0.0 | 0.0 | 264.0 | 0.0 |
| 18 | 7.0 | 228.0 | 27.0 | 2.0 |
| 19 | 5.0 | 24.0 | 233.0 | 2.0 |
| 20 | 2.0 | 3.0 | 46.0 | 213.0 |
| 21 | 9.0 | 7.0 | 214.0 | 34.0 |
| 22 | 29.0 | 20.0 | 145.0 | 70.0 |
| 23 | 38.25 | 99.25 | 84.25 | 42.25 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.22 | 0.17 | 0.333 | 0.277 |
| 02 | 0.281 | 0.05 | 0.569 | 0.099 |
| 03 | 0.208 | 0.004 | 0.383 | 0.405 |
| 04 | 0.152 | 0.0 | 0.848 | 0.0 |
| 05 | 0.0 | 0.0 | 1.0 | 0.0 |
| 06 | 0.0 | 0.0 | 1.0 | 0.0 |
| 07 | 0.004 | 0.996 | 0.0 | 0.0 |
| 08 | 0.0 | 0.0 | 1.0 | 0.0 |
| 09 | 0.0 | 0.0 | 0.004 | 0.996 |
| 10 | 0.019 | 0.0 | 0.973 | 0.008 |
| 11 | 0.136 | 0.011 | 0.542 | 0.311 |
| 12 | 0.163 | 0.515 | 0.223 | 0.098 |
| 13 | 0.307 | 0.045 | 0.58 | 0.068 |
| 14 | 0.159 | 0.0 | 0.379 | 0.462 |
| 15 | 0.152 | 0.0 | 0.826 | 0.023 |
| 16 | 0.0 | 0.004 | 0.996 | 0.0 |
| 17 | 0.0 | 0.0 | 1.0 | 0.0 |
| 18 | 0.027 | 0.864 | 0.102 | 0.008 |
| 19 | 0.019 | 0.091 | 0.883 | 0.008 |
| 20 | 0.008 | 0.011 | 0.174 | 0.807 |
| 21 | 0.034 | 0.027 | 0.811 | 0.129 |
| 22 | 0.11 | 0.076 | 0.549 | 0.265 |
| 23 | 0.145 | 0.376 | 0.319 | 0.16 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.126 | -0.373 | 0.282 | 0.099 |
| 02 | 0.115 | -1.527 | 0.811 | -0.891 |
| 03 | -0.178 | -3.338 | 0.418 | 0.475 |
| 04 | -0.487 | -3.878 | 1.207 | -3.878 |
| 05 | -3.878 | -3.878 | 1.371 | -3.878 |
| 06 | -3.878 | -3.878 | 1.371 | -3.878 |
| 07 | -3.338 | 1.367 | -3.878 | -3.878 |
| 08 | -3.878 | -3.878 | 1.371 | -3.878 |
| 09 | -3.878 | -3.878 | -3.338 | 1.367 |
| 10 | -2.355 | -3.878 | 1.344 | -2.989 |
| 11 | -0.589 | -2.73 | 0.762 | 0.213 |
| 12 | -0.417 | 0.712 | -0.11 | -0.9 |
| 13 | 0.201 | -1.616 | 0.829 | -1.246 |
| 14 | -0.44 | -3.878 | 0.408 | 0.605 |
| 15 | -0.487 | -3.878 | 1.18 | -2.21 |
| 16 | -3.878 | -3.338 | 1.367 | -3.878 |
| 17 | -3.878 | -3.878 | 1.371 | -3.878 |
| 18 | -2.083 | 1.225 | -0.864 | -2.989 |
| 19 | -2.355 | -0.976 | 1.246 | -2.989 |
| 20 | -2.989 | -2.73 | -0.352 | 1.157 |
| 21 | -1.869 | -2.083 | 1.162 | -0.644 |
| 22 | -0.796 | -1.147 | 0.776 | 0.058 |
| 23 | -0.531 | 0.401 | 0.24 | -0.434 |
| P-value | Threshold |
|---|---|
| 0.001 | -3.85954 |
| 0.0005 | -2.12669 |
| 0.0001 | 1.57191 |