KLF11.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF11.H12INVITRO.0.P.B
Gene (human)	KLF11 (GeneCards)
Gene synonyms (human)	FKLF, TIEG2
Gene (mouse)	Klf11
Gene synonyms (mouse)	Tieg2b, Tieg3
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	vvRGGGGCGGGRCbd
GC content	81.55%
Information content (bits; total / per base)	16.461 / 1.097
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (14)	0.79	0.806	0.622	0.651	0.856	0.864	3.245	3.371	49.2	58.658

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.878	0.812	0.848	0.784	0.796	0.741
Overall, 2 experiments	best	0.895	0.836	0.863	0.804	0.803	0.754
Methyl HT-SELEX, 1 experiments	median	0.86	0.789	0.833	0.764	0.789	0.728
Methyl HT-SELEX, 1 experiments	best	0.86	0.789	0.833	0.764	0.789	0.728
Non-Methyl HT-SELEX, 1 experiments	median	0.895	0.836	0.863	0.804	0.803	0.754
Non-Methyl HT-SELEX, 1 experiments	best	0.895	0.836	0.863	0.804	0.803	0.754

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.684	0.33	0.741	0.483

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.11
HGNC	HGNC:11811
MGI	MGI:2653368
EntrezGene (human)	GeneID:8462 (SSTAR profile)
EntrezGene (mouse)	GeneID:194655 (SSTAR profile)
UniProt ID (human)	KLF11_HUMAN
UniProt ID (mouse)	KLF11_MOUSE
UniProt AC (human)	O14901 (TFClass)
UniProt AC (mouse)	Q8K1S5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	KLF11.H12INVITRO.0.P.B.pcm
PWM	KLF11.H12INVITRO.0.P.B.pwm
PFM	KLF11.H12INVITRO.0.P.B.pfm
Alignment	KLF11.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	KLF11.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	KLF11.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	KLF11.H12INVITRO.0.P.B_meme_format.meme
Transfac format	KLF11.H12INVITRO.0.P.B_transfac_format.txt
Homer format	KLF11.H12INVITRO.0.P.B_homer_format_0.001.txt KLF11.H12INVITRO.0.P.B_homer_format_0.0005.txt KLF11.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	159.0	221.0	542.0	78.0
02	404.0	201.0	290.0	105.0
03	291.0	39.0	628.0	42.0
04	91.0	8.0	843.0	58.0
05	183.0	4.0	804.0	9.0
06	6.0	1.0	988.0	5.0
07	3.0	8.0	986.0	3.0
08	10.0	947.0	1.0	42.0
09	13.0	8.0	969.0	10.0
10	5.0	9.0	956.0	30.0
11	59.0	3.0	931.0	7.0
12	136.0	68.0	776.0	20.0
13	104.0	825.0	22.0	49.0
14	68.0	499.0	142.0	291.0
15	167.0	154.0	360.0	319.0

PFM

	A	C	G	T
01	0.159	0.221	0.542	0.078
02	0.404	0.201	0.29	0.105
03	0.291	0.039	0.628	0.042
04	0.091	0.008	0.843	0.058
05	0.183	0.004	0.804	0.009
06	0.006	0.001	0.988	0.005
07	0.003	0.008	0.986	0.003
08	0.01	0.947	0.001	0.042
09	0.013	0.008	0.969	0.01
10	0.005	0.009	0.956	0.03
11	0.059	0.003	0.931	0.007
12	0.136	0.068	0.776	0.02
13	0.104	0.825	0.022	0.049
14	0.068	0.499	0.142	0.291
15	0.167	0.154	0.36	0.319

PWM

	A	C	G	T
01	-0.449	-0.122	0.77	-1.15
02	0.477	-0.216	0.147	-0.858
03	0.151	-1.821	0.917	-1.75
04	-0.999	-3.253	1.211	-1.439
05	-0.309	-3.783	1.163	-3.156
06	-3.484	-4.525	1.369	-3.622
07	-3.975	-3.253	1.367	-3.975
08	-3.066	1.327	-4.525	-1.75
09	-2.839	-3.253	1.35	-3.066
10	-3.622	-3.156	1.336	-2.071
11	-1.422	-3.975	1.31	-3.362
12	-0.603	-1.284	1.128	-2.45
13	-0.867	1.189	-2.362	-1.602
14	-1.284	0.688	-0.56	0.151
15	-0.4	-0.48	0.363	0.242

Standard thresholds

P-value	Threshold
0.001	2.11581
0.0005	3.39691
0.0001	6.08166