KLF10.H12RSNP.0.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF10.H12RSNP.0.P.C
Gene (human)	KLF10 (GeneCards)
Gene synonyms (human)	TIEG, TIEG1
Gene (mouse)	Klf10
Gene synonyms (mouse)	Gdnfif, Tieg, Tieg1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	10
Consensus	RGGGGYGKGG
GC content	86.32%
Information content (bits; total / per base)	13.875 / 1.387
Data sources	ChIP-Seq
Aligned words	998

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.785	0.81	0.601	0.613	0.833	0.88	2.645	2.754	31.086	36.538

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.861	0.784	0.848	0.774	0.774	0.727
Overall, 2 experiments	best	0.862	0.789	0.856	0.777	0.827	0.757
Methyl HT-SELEX, 1 experiments	median	0.861	0.78	0.856	0.777	0.827	0.757
Methyl HT-SELEX, 1 experiments	best	0.861	0.78	0.856	0.777	0.827	0.757
Non-Methyl HT-SELEX, 1 experiments	median	0.862	0.789	0.841	0.77	0.72	0.698
Non-Methyl HT-SELEX, 1 experiments	best	0.862	0.789	0.841	0.77	0.72	0.698

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.86	0.139	0.832	0.571
batch 2	0.618	0.142	0.514	0.309

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.10
HGNC	HGNC:11810
MGI	MGI:1101353
EntrezGene (human)	GeneID:7071 (SSTAR profile)
EntrezGene (mouse)	GeneID:21847 (SSTAR profile)
UniProt ID (human)	KLF10_HUMAN
UniProt ID (mouse)	KLF10_MOUSE
UniProt AC (human)	Q13118 (TFClass)
UniProt AC (mouse)	O89091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	KLF10.H12RSNP.0.P.C.pcm
PWM	KLF10.H12RSNP.0.P.C.pwm
PFM	KLF10.H12RSNP.0.P.C.pfm
Alignment	KLF10.H12RSNP.0.P.C.words.tsv
Threshold to P-value map	KLF10.H12RSNP.0.P.C.thr
Motif in other formats
JASPAR format	KLF10.H12RSNP.0.P.C_jaspar_format.txt
MEME format	KLF10.H12RSNP.0.P.C_meme_format.meme
Transfac format	KLF10.H12RSNP.0.P.C_transfac_format.txt
Homer format	KLF10.H12RSNP.0.P.C_homer_format_0.001.txt KLF10.H12RSNP.0.P.C_homer_format_0.0005.txt KLF10.H12RSNP.0.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	264.0	11.0	696.0	27.0
02	56.0	7.0	840.0	95.0
03	93.0	6.0	894.0	5.0
04	4.0	0.0	990.0	4.0
05	3.0	2.0	991.0	2.0
06	47.0	725.0	1.0	225.0
07	18.0	4.0	956.0	20.0
08	7.0	22.0	669.0	300.0
09	11.0	0.0	977.0	10.0
10	42.0	20.0	804.0	132.0

PFM

	A	C	G	T
01	0.265	0.011	0.697	0.027
02	0.056	0.007	0.842	0.095
03	0.093	0.006	0.896	0.005
04	0.004	0.0	0.992	0.004
05	0.003	0.002	0.993	0.002
06	0.047	0.726	0.001	0.225
07	0.018	0.004	0.958	0.02
08	0.007	0.022	0.67	0.301
09	0.011	0.0	0.979	0.01
10	0.042	0.02	0.806	0.132

PWM

	A	C	G	T
01	0.056	-2.983	1.021	-2.169
02	-1.471	-3.36	1.209	-0.954
03	-0.975	-3.482	1.271	-3.62
04	-3.781	-4.98	1.373	-3.781
05	-3.973	-4.211	1.374	-4.211
06	-1.64	1.062	-4.523	-0.103
07	-2.544	-3.781	1.338	-2.448
08	-3.36	-2.36	0.982	0.183
09	-2.983	-4.98	1.36	-3.065
10	-1.748	-2.448	1.165	-0.631

Standard thresholds

P-value	Threshold
0.001	3.14594
0.0005	4.35069
0.0001	6.850185