KLF10.H12INVITRO.0.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF10.H12INVITRO.0.P.C
Gene (human)	KLF10 (GeneCards)
Gene synonyms (human)	TIEG, TIEG1
Gene (mouse)	Klf10
Gene synonyms (mouse)	Gdnfif, Tieg, Tieg1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	14
Consensus	RvhGRGGGYGKGGC
GC content	79.8%
Information content (bits; total / per base)	14.657 / 1.047
Data sources	ChIP-Seq
Aligned words	140

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.791	0.873	0.641	0.731	0.83	0.915	3.155	3.589	42.013	42.854

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.938	0.899	0.896	0.856	0.792	0.774
Overall, 2 experiments	best	0.949	0.913	0.921	0.881	0.853	0.819
Methyl HT-SELEX, 1 experiments	median	0.949	0.913	0.921	0.881	0.853	0.819
Methyl HT-SELEX, 1 experiments	best	0.949	0.913	0.921	0.881	0.853	0.819
Non-Methyl HT-SELEX, 1 experiments	median	0.927	0.885	0.872	0.83	0.731	0.729
Non-Methyl HT-SELEX, 1 experiments	best	0.927	0.885	0.872	0.83	0.731	0.729

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.86	0.014	0.697	0.357
batch 2	0.567	0.106	0.52	0.316

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.10
HGNC	HGNC:11810
MGI	MGI:1101353
EntrezGene (human)	GeneID:7071 (SSTAR profile)
EntrezGene (mouse)	GeneID:21847 (SSTAR profile)
UniProt ID (human)	KLF10_HUMAN
UniProt ID (mouse)	KLF10_MOUSE
UniProt AC (human)	Q13118 (TFClass)
UniProt AC (mouse)	O89091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	KLF10.H12INVITRO.0.P.C.pcm
PWM	KLF10.H12INVITRO.0.P.C.pwm
PFM	KLF10.H12INVITRO.0.P.C.pfm
Alignment	KLF10.H12INVITRO.0.P.C.words.tsv
Threshold to P-value map	KLF10.H12INVITRO.0.P.C.thr
Motif in other formats
JASPAR format	KLF10.H12INVITRO.0.P.C_jaspar_format.txt
MEME format	KLF10.H12INVITRO.0.P.C_meme_format.meme
Transfac format	KLF10.H12INVITRO.0.P.C_transfac_format.txt
Homer format	KLF10.H12INVITRO.0.P.C_homer_format_0.001.txt KLF10.H12INVITRO.0.P.C_homer_format_0.0005.txt KLF10.H12INVITRO.0.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	14.0	11.0	103.0	12.0
02	19.0	43.0	72.0	6.0
03	56.0	34.0	23.0	27.0
04	22.0	0.0	115.0	3.0
05	28.0	1.0	91.0	20.0
06	12.0	1.0	126.0	1.0
07	0.0	0.0	140.0	0.0
08	0.0	0.0	140.0	0.0
09	18.0	95.0	0.0	27.0
10	3.0	2.0	123.0	12.0
11	2.0	19.0	70.0	49.0
12	5.0	2.0	125.0	8.0
13	9.0	1.0	114.0	16.0
14	16.0	111.0	2.0	11.0

PFM

	A	C	G	T
01	0.1	0.079	0.736	0.086
02	0.136	0.307	0.514	0.043
03	0.4	0.243	0.164	0.193
04	0.157	0.0	0.821	0.021
05	0.2	0.007	0.65	0.143
06	0.086	0.007	0.9	0.007
07	0.0	0.0	1.0	0.0
08	0.0	0.0	1.0	0.0
09	0.129	0.679	0.0	0.193
10	0.021	0.014	0.879	0.086
11	0.014	0.136	0.5	0.35
12	0.036	0.014	0.893	0.057
13	0.064	0.007	0.814	0.114
14	0.114	0.793	0.014	0.079

PWM

	A	C	G	T
01	-0.866	-1.086	1.057	-1.007
02	-0.583	0.199	0.704	-1.611
03	0.457	-0.028	-0.402	-0.249
04	-0.444	-3.379	1.166	-2.147
05	-0.215	-2.786	0.934	-0.534
06	-1.007	-2.786	1.256	-2.786
07	-3.379	-3.379	1.36	-3.379
08	-3.379	-3.379	1.36	-3.379
09	-0.633	0.977	-3.379	-0.249
10	-2.147	-2.416	1.232	-1.007
11	-2.416	-0.583	0.676	0.327
12	-1.76	-2.416	1.248	-1.367
13	-1.264	-2.786	1.157	-0.743
14	-0.743	1.131	-2.416	-1.086

Standard thresholds

P-value	Threshold
0.001	3.66981
0.0005	4.71751
0.0001	6.89791