KLF10.H12CORE.0.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF10.H12CORE.0.P.C
Gene (human)	KLF10 (GeneCards)
Gene synonyms (human)	TIEG, TIEG1
Gene (mouse)	Klf10
Gene synonyms (mouse)	Gdnfif, Tieg, Tieg1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	15
Consensus	vvnRKGGGYGKGKMb
GC content	77.87%
Information content (bits; total / per base)	13.776 / 0.918
Data sources	ChIP-Seq
Aligned words	978

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.801	0.853	0.662	0.689	0.846	0.91	3.271	3.484	44.367	52.187

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.914	0.861	0.877	0.825	0.781	0.754
Overall, 2 experiments	best	0.923	0.872	0.896	0.844	0.838	0.793
Methyl HT-SELEX, 1 experiments	median	0.923	0.872	0.896	0.844	0.838	0.793
Methyl HT-SELEX, 1 experiments	best	0.923	0.872	0.896	0.844	0.838	0.793
Non-Methyl HT-SELEX, 1 experiments	median	0.905	0.85	0.859	0.806	0.724	0.716
Non-Methyl HT-SELEX, 1 experiments	best	0.905	0.85	0.859	0.806	0.724	0.716

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.899	0.049	0.784	0.5
batch 2	0.525	0.124	0.542	0.339

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.10
HGNC	HGNC:11810
MGI	MGI:1101353
EntrezGene (human)	GeneID:7071 (SSTAR profile)
EntrezGene (mouse)	GeneID:21847 (SSTAR profile)
UniProt ID (human)	KLF10_HUMAN
UniProt ID (mouse)	KLF10_MOUSE
UniProt AC (human)	Q13118 (TFClass)
UniProt AC (mouse)	O89091 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	KLF10.H12CORE.0.P.C.pcm
PWM	KLF10.H12CORE.0.P.C.pwm
PFM	KLF10.H12CORE.0.P.C.pfm
Alignment	KLF10.H12CORE.0.P.C.words.tsv
Threshold to P-value map	KLF10.H12CORE.0.P.C.thr
Motif in other formats
JASPAR format	KLF10.H12CORE.0.P.C_jaspar_format.txt
MEME format	KLF10.H12CORE.0.P.C_meme_format.meme
Transfac format	KLF10.H12CORE.0.P.C_transfac_format.txt
Homer format	KLF10.H12CORE.0.P.C_homer_format_0.001.txt KLF10.H12CORE.0.P.C_homer_format_0.0005.txt KLF10.H12CORE.0.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	163.0	162.0	555.0	98.0
02	195.0	213.0	482.0	88.0
03	366.0	206.0	233.0	173.0
04	173.0	20.0	747.0	38.0
05	98.0	12.0	736.0	132.0
06	155.0	7.0	812.0	4.0
07	8.0	8.0	953.0	9.0
08	6.0	8.0	960.0	4.0
09	60.0	650.0	4.0	264.0
10	23.0	17.0	908.0	30.0
11	7.0	54.0	595.0	322.0
12	39.0	6.0	890.0	43.0
13	63.0	25.0	746.0	144.0
14	101.0	725.0	90.0	62.0
15	123.0	431.0	169.0	255.0

PFM

	A	C	G	T
01	0.167	0.166	0.567	0.1
02	0.199	0.218	0.493	0.09
03	0.374	0.211	0.238	0.177
04	0.177	0.02	0.764	0.039
05	0.1	0.012	0.753	0.135
06	0.158	0.007	0.83	0.004
07	0.008	0.008	0.974	0.009
08	0.006	0.008	0.982	0.004
09	0.061	0.665	0.004	0.27
10	0.024	0.017	0.928	0.031
11	0.007	0.055	0.608	0.329
12	0.04	0.006	0.91	0.044
13	0.064	0.026	0.763	0.147
14	0.103	0.741	0.092	0.063
15	0.126	0.441	0.173	0.261

PWM

	A	C	G	T
01	-0.402	-0.408	0.816	-0.904
02	-0.224	-0.137	0.675	-1.01
03	0.401	-0.17	-0.048	-0.343
04	-0.343	-2.428	1.112	-1.824
05	-0.904	-2.887	1.097	-0.61
06	-0.452	-3.34	1.195	-3.762
07	-3.232	-3.232	1.355	-3.134
08	-3.462	-3.232	1.362	-3.762
09	-1.384	0.973	-3.762	0.076
10	-2.299	-2.577	1.307	-2.049
11	-3.34	-1.486	0.885	0.274
12	-1.799	-3.462	1.287	-1.706
13	-1.336	-2.221	1.111	-0.525
14	-0.874	1.082	-0.987	-1.352
15	-0.68	0.564	-0.366	0.042

Standard thresholds

P-value	Threshold
0.001	3.56506
0.0005	4.64081
0.0001	6.87506