KLF1.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF1.H12RSNP.0.P.B
Gene (human)	KLF1 (GeneCards)
Gene synonyms (human)	EKLF
Gene (mouse)	Klf1
Gene synonyms (mouse)	Elkf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	ndGGGYGKRGYbb
GC content	74.68%
Information content (bits; total / per base)	11.795 / 0.907
Data sources	ChIP-Seq
Aligned words	996

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	4 (25)	0.792	0.881	0.654	0.755	0.807	0.897	2.709	3.229	86.921	212.387
Mouse	2 (14)	0.899	0.926	0.776	0.816	0.901	0.918	3.312	3.44	141.196	179.699

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	4.517	2.456	0.093	0.049

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.1
HGNC	HGNC:6345
MGI	MGI:1342771
EntrezGene (human)	GeneID:10661 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	KLF1_HUMAN
UniProt ID (mouse)	KLF1_MOUSE
UniProt AC (human)	Q13351 (TFClass)
UniProt AC (mouse)	P46099 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	4 human, 2 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	KLF1.H12RSNP.0.P.B.pcm
PWM	KLF1.H12RSNP.0.P.B.pwm
PFM	KLF1.H12RSNP.0.P.B.pfm
Alignment	KLF1.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	KLF1.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	KLF1.H12RSNP.0.P.B_jaspar_format.txt
MEME format	KLF1.H12RSNP.0.P.B_meme_format.meme
Transfac format	KLF1.H12RSNP.0.P.B_transfac_format.txt
Homer format	KLF1.H12RSNP.0.P.B_homer_format_0.001.txt KLF1.H12RSNP.0.P.B_homer_format_0.0005.txt KLF1.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	321.0	309.0	232.0	134.0
02	436.0	41.0	274.0	245.0
03	14.0	2.0	972.0	8.0
04	21.0	7.0	965.0	3.0
05	5.0	7.0	980.0	4.0
06	76.0	591.0	0.0	329.0
07	10.0	9.0	945.0	32.0
08	22.0	35.0	554.0	385.0
09	115.0	12.0	765.0	104.0
10	71.0	24.0	814.0	87.0
11	70.0	659.0	90.0	177.0
12	104.0	500.0	183.0	209.0
13	134.0	326.0	374.0	162.0

PFM

	A	C	G	T
01	0.322	0.31	0.233	0.135
02	0.438	0.041	0.275	0.246
03	0.014	0.002	0.976	0.008
04	0.021	0.007	0.969	0.003
05	0.005	0.007	0.984	0.004
06	0.076	0.593	0.0	0.33
07	0.01	0.009	0.949	0.032
08	0.022	0.035	0.556	0.387
09	0.115	0.012	0.768	0.104
10	0.071	0.024	0.817	0.087
11	0.07	0.662	0.09	0.178
12	0.104	0.502	0.184	0.21
13	0.135	0.327	0.376	0.163

PWM

	A	C	G	T
01	0.252	0.215	-0.07	-0.614
02	0.557	-1.77	0.095	-0.016
03	-2.769	-4.209	1.357	-3.25
04	-2.401	-3.358	1.35	-3.971
05	-3.618	-3.358	1.365	-3.779
06	-1.171	0.86	-4.979	0.277
07	-3.063	-3.152	1.329	-2.006
08	-2.358	-1.921	0.796	0.433
09	-0.765	-2.905	1.118	-0.864
10	-1.238	-2.277	1.18	-1.039
11	-1.252	0.969	-1.006	-0.339
12	-0.864	0.694	-0.305	-0.174
13	-0.614	0.268	0.404	-0.426

Standard thresholds

P-value	Threshold
0.001	4.18621
0.0005	5.20971
0.0001	7.293065