KLF1.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF1.H12INVIVO.0.P.B
Gene (human)	KLF1 (GeneCards)
Gene synonyms (human)	EKLF
Gene (mouse)	Klf1
Gene synonyms (mouse)	Elkf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	vdGGGYGKKGYbb
GC content	74.79%
Information content (bits; total / per base)	11.998 / 0.923
Data sources	ChIP-Seq
Aligned words	999

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	4 (25)	0.794	0.88	0.659	0.757	0.807	0.9	2.732	3.246	87.585	213.31
Mouse	2 (14)	0.9	0.926	0.779	0.819	0.9	0.917	3.323	3.445	140.465	176.469

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	4.428	2.428	0.087	0.048

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.1
HGNC	HGNC:6345
MGI	MGI:1342771
EntrezGene (human)	GeneID:10661 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	KLF1_HUMAN
UniProt ID (mouse)	KLF1_MOUSE
UniProt AC (human)	Q13351 (TFClass)
UniProt AC (mouse)	P46099 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	4 human, 2 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	KLF1.H12INVIVO.0.P.B.pcm
PWM	KLF1.H12INVIVO.0.P.B.pwm
PFM	KLF1.H12INVIVO.0.P.B.pfm
Alignment	KLF1.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	KLF1.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	KLF1.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	KLF1.H12INVIVO.0.P.B_meme_format.meme
Transfac format	KLF1.H12INVIVO.0.P.B_transfac_format.txt
Homer format	KLF1.H12INVIVO.0.P.B_homer_format_0.001.txt KLF1.H12INVIVO.0.P.B_homer_format_0.0005.txt KLF1.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	302.0	334.0	242.0	121.0
02	454.0	36.0	250.0	259.0
03	9.0	3.0	970.0	17.0
04	10.0	2.0	984.0	3.0
05	9.0	10.0	977.0	3.0
06	88.0	586.0	2.0	323.0
07	7.0	8.0	965.0	19.0
08	38.0	48.0	513.0	400.0
09	108.0	14.0	768.0	109.0
10	41.0	28.0	843.0	87.0
11	61.0	670.0	63.0	205.0
12	97.0	494.0	181.0	227.0
13	101.0	337.0	385.0	176.0

PFM

	A	C	G	T
01	0.302	0.334	0.242	0.121
02	0.454	0.036	0.25	0.259
03	0.009	0.003	0.971	0.017
04	0.01	0.002	0.985	0.003
05	0.009	0.01	0.978	0.003
06	0.088	0.587	0.002	0.323
07	0.007	0.008	0.966	0.019
08	0.038	0.048	0.514	0.4
09	0.108	0.014	0.769	0.109
10	0.041	0.028	0.844	0.087
11	0.061	0.671	0.063	0.205
12	0.097	0.494	0.181	0.227
13	0.101	0.337	0.385	0.176

PWM

	A	C	G	T
01	0.189	0.289	-0.031	-0.717
02	0.595	-1.897	0.001	0.036
03	-3.155	-3.974	1.352	-2.597
04	-3.065	-4.212	1.366	-3.974
05	-3.155	-3.065	1.359	-3.974
06	-1.031	0.849	-4.212	0.256
07	-3.361	-3.252	1.347	-2.496
08	-1.845	-1.621	0.716	0.468
09	-0.829	-2.772	1.119	-0.82
10	-1.773	-2.135	1.212	-1.042
11	-1.389	0.983	-1.357	-0.196
12	-0.935	0.679	-0.319	-0.095
13	-0.895	0.298	0.43	-0.347

Standard thresholds

P-value	Threshold
0.001	4.10191
0.0005	5.14126
0.0001	7.262665