JUNB.H12RSNP.0.PM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	JUNB.H12RSNP.0.PM.A
Gene (human)	JUNB (GeneCards)
Gene synonyms (human)
Gene (mouse)	Junb
Gene synonyms (mouse)	Jun-b
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	9
Consensus	nTKAGYMAb
GC content	42.5%
Information content (bits; total / per base)	7.816 / 0.868
Data sources	ChIP-Seq + Methyl-HT-SELEX
Aligned words	985

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	22 (137)	0.91	0.986	0.862	0.975	0.905	0.972	3.4	4.334	163.409	503.921
Mouse	25 (148)	0.895	0.966	0.841	0.937	0.872	0.954	3.103	3.843	172.562	373.523

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.719	0.712	0.627	0.626	0.573	0.578
Overall, 2 experiments	best	0.824	0.821	0.686	0.69	0.601	0.616
Methyl HT-SELEX, 1 experiments	median	0.824	0.821	0.686	0.69	0.601	0.616
Methyl HT-SELEX, 1 experiments	best	0.824	0.821	0.686	0.69	0.601	0.616
Non-Methyl HT-SELEX, 1 experiments	median	0.614	0.604	0.569	0.562	0.544	0.541
Non-Methyl HT-SELEX, 1 experiments	best	0.614	0.604	0.569	0.562	0.544	0.541

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.572	0.092	0.116	0.126

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	Jun {1.1.1.1} (TFClass)
TFClass ID	TFClass: 1.1.1.1.2
HGNC	HGNC:6205
MGI	MGI:96647
EntrezGene (human)	GeneID:3726 (SSTAR profile)
EntrezGene (mouse)	GeneID:16477 (SSTAR profile)
UniProt ID (human)	JUNB_HUMAN
UniProt ID (mouse)	JUNB_MOUSE
UniProt AC (human)	P17275 (TFClass)
UniProt AC (mouse)	P09450 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	22 human, 25 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	JUNB.H12RSNP.0.PM.A.pcm
PWM	JUNB.H12RSNP.0.PM.A.pwm
PFM	JUNB.H12RSNP.0.PM.A.pfm
Alignment	JUNB.H12RSNP.0.PM.A.words.tsv
Threshold to P-value map	JUNB.H12RSNP.0.PM.A.thr
Motif in other formats
JASPAR format	JUNB.H12RSNP.0.PM.A_jaspar_format.txt
MEME format	JUNB.H12RSNP.0.PM.A_meme_format.meme
Transfac format	JUNB.H12RSNP.0.PM.A_transfac_format.txt
Homer format	JUNB.H12RSNP.0.PM.A_homer_format_0.001.txt JUNB.H12RSNP.0.PM.A_homer_format_0.0005.txt JUNB.H12RSNP.0.PM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	333.0	258.0	274.0	120.0
02	59.0	12.0	68.0	846.0
03	54.0	65.0	722.0	144.0
04	727.0	14.0	17.0	227.0
05	0.0	0.0	793.0	192.0
06	87.0	128.0	58.0	712.0
07	110.0	777.0	42.0	56.0
08	933.0	17.0	6.0	29.0
09	92.0	259.0	258.0	376.0

PFM

	A	C	G	T
01	0.338	0.262	0.278	0.122
02	0.06	0.012	0.069	0.859
03	0.055	0.066	0.733	0.146
04	0.738	0.014	0.017	0.23
05	0.0	0.0	0.805	0.195
06	0.088	0.13	0.059	0.723
07	0.112	0.789	0.043	0.057
08	0.947	0.017	0.006	0.029
09	0.093	0.263	0.262	0.382

PWM

	A	C	G	T
01	0.3	0.046	0.106	-0.712
02	-1.407	-2.894	-1.269	1.229
03	-1.493	-1.313	1.071	-0.532
04	1.078	-2.758	-2.584	-0.081
05	-4.969	-4.969	1.165	-0.247
06	-1.028	-0.648	-1.424	1.057
07	-0.797	1.144	-1.735	-1.458
08	1.327	-2.584	-3.469	-2.088
09	-0.973	0.05	0.046	0.421

Standard thresholds

P-value	Threshold
0.001	5.02639
0.0005	5.764415
0.0001	7.04079