JUNB.H12INVIVO.1.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	JUNB.H12INVIVO.1.S.C
Gene (human)	JUNB (GeneCards)
Gene synonyms (human)
Gene (mouse)	Junb
Gene synonyms (mouse)	Jun-b
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	15
Consensus	nRTGACGTCATSvhn
GC content	50.68%
Information content (bits; total / per base)	17.17 / 1.145
Data sources	HT-SELEX
Aligned words	556

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	22 (137)	0.566	0.611	0.414	0.466	0.509	0.553	1.161	1.395	4.367	12.194
Mouse	25 (148)	0.568	0.659	0.409	0.518	0.51	0.623	1.156	1.683	7.131	31.432

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.71	0.675	0.653	0.622	0.611	0.589
Overall, 2 experiments	best	0.731	0.687	0.671	0.634	0.626	0.599
Methyl HT-SELEX, 1 experiments	median	0.731	0.687	0.671	0.634	0.626	0.599
Methyl HT-SELEX, 1 experiments	best	0.731	0.687	0.671	0.634	0.626	0.599
Non-Methyl HT-SELEX, 1 experiments	median	0.688	0.663	0.636	0.61	0.597	0.578
Non-Methyl HT-SELEX, 1 experiments	best	0.688	0.663	0.636	0.61	0.597	0.578

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.514	0.081	-0.048	-0.016

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	Jun {1.1.1.1} (TFClass)
TFClass ID	TFClass: 1.1.1.1.2
HGNC	HGNC:6205
MGI	MGI:96647
EntrezGene (human)	GeneID:3726 (SSTAR profile)
EntrezGene (mouse)	GeneID:16477 (SSTAR profile)
UniProt ID (human)	JUNB_HUMAN
UniProt ID (mouse)	JUNB_MOUSE
UniProt AC (human)	P17275 (TFClass)
UniProt AC (mouse)	P09450 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	22 human, 25 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	JUNB.H12INVIVO.1.S.C.pcm
PWM	JUNB.H12INVIVO.1.S.C.pwm
PFM	JUNB.H12INVIVO.1.S.C.pfm
Alignment	JUNB.H12INVIVO.1.S.C.words.tsv
Threshold to P-value map	JUNB.H12INVIVO.1.S.C.thr
Motif in other formats
JASPAR format	JUNB.H12INVIVO.1.S.C_jaspar_format.txt
MEME format	JUNB.H12INVIVO.1.S.C_meme_format.meme
Transfac format	JUNB.H12INVIVO.1.S.C_transfac_format.txt
Homer format	JUNB.H12INVIVO.1.S.C_homer_format_0.001.txt JUNB.H12INVIVO.1.S.C_homer_format_0.0005.txt JUNB.H12INVIVO.1.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	119.75	133.75	152.75	149.75
02	400.5	43.5	100.5	11.5
03	14.0	15.0	7.0	520.0
04	3.0	16.0	479.0	58.0
05	534.0	7.0	15.0	0.0
06	0.0	555.0	0.0	1.0
07	1.0	3.0	552.0	0.0
08	0.0	1.0	0.0	555.0
09	8.0	545.0	0.0	3.0
10	548.0	7.0	1.0	0.0
11	2.0	151.0	2.0	401.0
12	26.0	411.0	71.0	48.0
13	138.0	176.0	177.0	65.0
14	87.5	211.5	73.5	183.5
15	74.5	177.5	142.5	161.5

PFM

	A	C	G	T
01	0.215	0.241	0.275	0.269
02	0.72	0.078	0.181	0.021
03	0.025	0.027	0.013	0.935
04	0.005	0.029	0.862	0.104
05	0.96	0.013	0.027	0.0
06	0.0	0.998	0.0	0.002
07	0.002	0.005	0.993	0.0
08	0.0	0.002	0.0	0.998
09	0.014	0.98	0.0	0.005
10	0.986	0.013	0.002	0.0
11	0.004	0.272	0.004	0.721
12	0.047	0.739	0.128	0.086
13	0.248	0.317	0.318	0.117
14	0.157	0.38	0.132	0.33
15	0.134	0.319	0.256	0.29

PWM

	A	C	G	T
01	-0.147	-0.038	0.093	0.074
02	1.051	-1.137	-0.32	-2.375
03	-2.2	-2.138	-2.796	1.311
04	-3.424	-2.079	1.229	-0.858
05	1.338	-2.796	-2.138	-4.488
06	-4.488	1.376	-4.488	-3.998
07	-3.998	-3.424	1.371	-4.488
08	-4.488	-3.998	-4.488	1.376
09	-2.686	1.358	-4.488	-3.424
10	1.363	-2.796	-3.998	-4.488
11	-3.67	0.082	-3.67	1.052
12	-1.629	1.077	-0.661	-1.042
13	-0.007	0.234	0.239	-0.747
14	-0.456	0.416	-0.627	0.275
15	-0.614	0.242	0.025	0.148

Standard thresholds

P-value	Threshold
0.001	1.35301
0.0005	2.75671
0.0001	5.71936