JUN.H12INVIVO.1.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	JUN.H12INVIVO.1.S.C
Gene (human)	JUN (GeneCards)
Gene synonyms (human)
Gene (mouse)	Jun
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	16
Consensus	nvRTKACGTCATCvnn
GC content	50.83%
Information content (bits; total / per base)	17.303 / 1.081
Data sources	HT-SELEX
Aligned words	140

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	64 (409)	0.557	0.831	0.409	0.838	0.548	0.905	1.37	6.408	11.215	424.638
Mouse	29 (173)	0.602	0.654	0.473	0.531	0.636	0.71	1.768	2.222	38.921	117.167

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.683	0.665	0.619	0.603	0.58	0.57
Non-Methyl HT-SELEX, 1 experiments	best	0.683	0.665	0.619	0.603	0.58	0.57

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.305	4.105	0.105	0.084

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.707	0.238	0.565	0.296
batch 2	0.882	0.85	0.91	0.644

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	Jun {1.1.1.1} (TFClass)
TFClass ID	TFClass: 1.1.1.1.1
HGNC	HGNC:6204
MGI	MGI:96646
EntrezGene (human)	GeneID:3725 (SSTAR profile)
EntrezGene (mouse)	GeneID:16476 (SSTAR profile)
UniProt ID (human)	JUN_HUMAN
UniProt ID (mouse)	JUN_MOUSE
UniProt AC (human)	P05412 (TFClass)
UniProt AC (mouse)	P05627 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	64 human, 29 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	JUN.H12INVIVO.1.S.C.pcm
PWM	JUN.H12INVIVO.1.S.C.pwm
PFM	JUN.H12INVIVO.1.S.C.pfm
Alignment	JUN.H12INVIVO.1.S.C.words.tsv
Threshold to P-value map	JUN.H12INVIVO.1.S.C.thr
Motif in other formats
JASPAR format	JUN.H12INVIVO.1.S.C_jaspar_format.txt
MEME format	JUN.H12INVIVO.1.S.C_meme_format.meme
Transfac format	JUN.H12INVIVO.1.S.C_transfac_format.txt
Homer format	JUN.H12INVIVO.1.S.C_homer_format_0.001.txt JUN.H12INVIVO.1.S.C_homer_format_0.0005.txt JUN.H12INVIVO.1.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	18.25	36.25	50.25	35.25
02	25.25	40.25	56.25	18.25
03	103.0	13.0	22.0	2.0
04	5.0	1.0	0.0	134.0
05	2.0	5.0	105.0	28.0
06	125.0	4.0	11.0	0.0
07	0.0	140.0	0.0	0.0
08	0.0	10.0	130.0	0.0
09	0.0	0.0	0.0	140.0
10	1.0	133.0	0.0	6.0
11	136.0	4.0	0.0	0.0
12	0.0	21.0	1.0	118.0
13	3.0	116.0	13.0	8.0
14	25.0	68.0	29.0	18.0
15	11.25	50.25	11.25	67.25
16	29.5	33.5	34.5	42.5

PFM

	A	C	G	T
01	0.13	0.259	0.359	0.252
02	0.18	0.288	0.402	0.13
03	0.736	0.093	0.157	0.014
04	0.036	0.007	0.0	0.957
05	0.014	0.036	0.75	0.2
06	0.893	0.029	0.079	0.0
07	0.0	1.0	0.0	0.0
08	0.0	0.071	0.929	0.0
09	0.0	0.0	0.0	1.0
10	0.007	0.95	0.0	0.043
11	0.971	0.029	0.0	0.0
12	0.0	0.15	0.007	0.843
13	0.021	0.829	0.093	0.057
14	0.179	0.486	0.207	0.129
15	0.08	0.359	0.08	0.48
16	0.211	0.239	0.246	0.304

PWM

	A	C	G	T
01	-0.62	0.034	0.351	0.007
02	-0.313	0.135	0.461	-0.62
03	1.057	-0.934	-0.444	-2.416
04	-1.76	-2.786	-3.379	1.317
05	-2.416	-1.76	1.076	-0.215
06	1.248	-1.935	-1.086	-3.379
07	-3.379	1.36	-3.379	-3.379
08	-3.379	-1.171	1.287	-3.379
09	-3.379	-3.379	-3.379	1.36
10	-2.786	1.31	-3.379	-1.611
11	1.332	-1.935	-3.379	-3.379
12	-3.379	-0.488	-2.786	1.191
13	-2.147	1.174	-0.934	-1.367
14	-0.323	0.647	-0.181	-0.633
15	-1.065	0.351	-1.065	0.637
16	-0.165	-0.042	-0.014	0.188

Standard thresholds

P-value	Threshold
0.001	2.52206
0.0005	3.73096
0.0001	6.27366