JUN.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	JUN.H12INVITRO.0.P.B
Gene (human)	JUN (GeneCards)
Gene synonyms (human)
Gene (mouse)	Jun
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	bvvTGAGTCAYb
GC content	49.79%
Information content (bits; total / per base)	14.6 / 1.217
Data sources	ChIP-Seq
Aligned words	593

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	64 (409)	0.846	0.979	0.79	0.948	0.814	0.972	3.415	5.224	165.276	542.921
Mouse	29 (173)	0.869	0.942	0.802	0.91	0.851	0.933	3.277	4.468	172.076	367.959

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.657	0.623	0.604	0.581	0.575	0.559
Non-Methyl HT-SELEX, 1 experiments	best	0.657	0.623	0.604	0.581	0.575	0.559

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	17.51	30.211	0.285	0.277

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.895	0.676	0.892	0.619
batch 2	0.634	0.268	0.412	0.511

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	Jun {1.1.1.1} (TFClass)
TFClass ID	TFClass: 1.1.1.1.1
HGNC	HGNC:6204
MGI	MGI:96646
EntrezGene (human)	GeneID:3725 (SSTAR profile)
EntrezGene (mouse)	GeneID:16476 (SSTAR profile)
UniProt ID (human)	JUN_HUMAN
UniProt ID (mouse)	JUN_MOUSE
UniProt AC (human)	P05412 (TFClass)
UniProt AC (mouse)	P05627 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	64 human, 29 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	JUN.H12INVITRO.0.P.B.pcm
PWM	JUN.H12INVITRO.0.P.B.pwm
PFM	JUN.H12INVITRO.0.P.B.pfm
Alignment	JUN.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	JUN.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	JUN.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	JUN.H12INVITRO.0.P.B_meme_format.meme
Transfac format	JUN.H12INVITRO.0.P.B_transfac_format.txt
Homer format	JUN.H12INVITRO.0.P.B_homer_format_0.001.txt JUN.H12INVITRO.0.P.B_homer_format_0.0005.txt JUN.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	102.0	123.0	258.0	110.0
02	159.0	101.0	252.0	81.0
03	243.0	102.0	207.0	41.0
04	0.0	0.0	8.0	585.0
05	12.0	0.0	580.0	1.0
06	559.0	25.0	0.0	9.0
07	13.0	0.0	580.0	0.0
08	0.0	0.0	0.0	593.0
09	2.0	591.0	0.0	0.0
10	593.0	0.0	0.0	0.0
11	4.0	236.0	51.0	302.0
12	60.0	319.0	110.0	104.0

PFM

	A	C	G	T
01	0.172	0.207	0.435	0.185
02	0.268	0.17	0.425	0.137
03	0.41	0.172	0.349	0.069
04	0.0	0.0	0.013	0.987
05	0.02	0.0	0.978	0.002
06	0.943	0.042	0.0	0.015
07	0.022	0.0	0.978	0.0
08	0.0	0.0	0.0	1.0
09	0.003	0.997	0.0	0.0
10	1.0	0.0	0.0	0.0
11	0.007	0.398	0.086	0.509
12	0.101	0.538	0.185	0.175

PWM

	A	C	G	T
01	-0.369	-0.185	0.55	-0.295
02	0.069	-0.379	0.526	-0.596
03	0.49	-0.369	0.331	-1.258
04	-4.542	-4.542	-2.748	1.365
05	-2.4	-4.542	1.356	-4.056
06	1.319	-1.729	-4.542	-2.649
07	-2.329	-4.542	1.356	-4.542
08	-4.542	-4.542	-4.542	1.378
09	-3.73	1.375	-4.542	-4.542
10	1.378	-4.542	-4.542	-4.542
11	-3.288	0.461	-1.047	0.706
12	-0.889	0.761	-0.295	-0.35

Standard thresholds

P-value	Threshold
0.001	2.414885
0.0005	3.87243
0.0001	6.43011