MotifISX.H12CORE.1.S.B
Gene (human)ISX
(GeneCards)
Gene synonyms (human)RAXLX
Gene (mouse)Isx
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length17
ConsensusnvbTAATTARhYWAdhd
GC content25.4%
Information content (bits; total / per base)16.507 / 0.971
Data sourcesHT-SELEX
Aligned words4776

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.992 0.988 0.983 0.974 0.97 0.957
best 0.999 0.998 0.996 0.995 0.99 0.986
Methyl HT-SELEX, 2 experiments median 0.995 0.992 0.989 0.984 0.978 0.968
best 0.999 0.998 0.996 0.995 0.99 0.986
Non-Methyl HT-SELEX, 6 experiments median 0.992 0.988 0.975 0.965 0.891 0.894
best 0.998 0.997 0.994 0.991 0.987 0.981

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.914 0.654 0.88 0.53
batch 2 0.731 0.321 0.761 0.572
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyPaired-related HD {3.1.3} (TFClass)
TF subfamilyISX {3.1.3.12} (TFClass)
TFClass IDTFClass: 3.1.3.12.1
HGNCHGNC:28084
MGIMGI:1918847
EntrezGene (human)GeneID:91464
(SSTAR profile)
EntrezGene (mouse)GeneID:71597
(SSTAR profile)
UniProt ID (human)ISX_HUMAN
UniProt ID (mouse)ISX_MOUSE
UniProt AC (human)Q2M1V0
(TFClass)
UniProt AC (mouse)A1A546
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
011454.751166.751150.751003.75
021221.5632.52606.5315.5
03358.02228.0693.01497.0
040.0114.01.04661.0
054776.00.00.00.0
064776.00.00.00.0
070.00.00.04776.0
080.00.00.04776.0
093861.00.0915.00.0
101118.0178.03474.06.0
112825.0934.0408.0609.0
12301.0640.0330.03505.0
131054.0322.0141.03259.0
144139.0184.082.0371.0
152200.0564.0705.01307.0
16783.251237.25471.252284.25
171345.5671.5773.51985.5
PFM
ACGT
010.3050.2440.2410.21
020.2560.1320.5460.066
030.0750.4660.1450.313
040.00.0240.00.976
051.00.00.00.0
061.00.00.00.0
070.00.00.01.0
080.00.00.01.0
090.8080.00.1920.0
100.2340.0370.7270.001
110.5910.1960.0850.128
120.0630.1340.0690.734
130.2210.0670.030.682
140.8670.0390.0170.078
150.4610.1180.1480.274
160.1640.2590.0990.478
170.2820.1410.1620.416
PWM
ACGT
010.197-0.023-0.037-0.173
020.023-0.6340.78-1.326
03-1.20.623-0.5430.226
04-6.336-2.332-5.951.361
051.385-6.336-6.336-6.336
061.385-6.336-6.336-6.336
07-6.336-6.336-6.3361.385
08-6.336-6.336-6.3361.385
091.172-6.336-0.266-6.336
10-0.066-1.8931.067-4.993
110.86-0.245-1.07-0.672
12-1.373-0.622-1.2811.076
13-0.124-1.306-2.1231.003
141.242-1.86-2.655-1.165
150.61-0.748-0.5260.09
16-0.4210.036-0.9270.648
170.119-0.574-0.4330.508
Standard thresholds
P-value Threshold
0.001 0.18686
0.0005 1.93311
0.0001 5.71296