MotifISL2.H12CORE.0.SM.B
Gene (human)ISL2
(GeneCards)
Gene synonyms (human)
Gene (mouse)Isl2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusnvbTAATTRvn
GC content40.6%
Information content (bits; total / per base)9.542 / 0.867
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9713

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.953 0.924 0.919 0.886 0.831 0.808
best 0.96 0.939 0.933 0.9 0.887 0.852
Methyl HT-SELEX, 1 experiments median 0.957 0.931 0.933 0.9 0.887 0.852
best 0.957 0.931 0.933 0.9 0.887 0.852
Non-Methyl HT-SELEX, 3 experiments median 0.949 0.917 0.914 0.885 0.798 0.787
best 0.96 0.939 0.924 0.886 0.864 0.829
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-LIM {3.1.5} (TFClass)
TF subfamilyISL {3.1.5.1} (TFClass)
TFClass IDTFClass: 3.1.5.1.2
HGNCHGNC:18524
MGIMGI:109156
EntrezGene (human)GeneID:64843
(SSTAR profile)
EntrezGene (mouse)GeneID:104360
(SSTAR profile)
UniProt ID (human)ISL2_HUMAN
UniProt ID (mouse)ISL2_MOUSE
UniProt AC (human)Q96A47
(TFClass)
UniProt AC (mouse)Q9CXV0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011954.753607.752310.751839.75
022862.52298.53618.5933.5
03556.03429.01468.04260.0
04109.04.035.09565.0
059713.00.00.00.0
069712.01.00.00.0
070.00.04277.05436.0
0817.03.03270.06423.0
091600.0669.07333.0111.0
102393.754243.752209.75865.75
112439.52520.52078.52674.5
PFM
ACGT
010.2010.3710.2380.189
020.2950.2370.3730.096
030.0570.3530.1510.439
040.0110.00.0040.985
051.00.00.00.0
061.00.00.00.0
070.00.00.440.56
080.0020.00.3370.661
090.1650.0690.7550.011
100.2460.4370.2280.089
110.2510.2590.2140.275
PWM
ACGT
01-0.2170.396-0.05-0.277
020.164-0.0550.399-0.954
03-1.4710.345-0.5030.562
04-3.084-5.956-4.1771.37
051.386-6.965-6.965-6.965
061.385-6.603-6.965-6.965
07-6.965-6.9650.5660.805
08-4.836-6.1290.2970.972
09-0.417-1.2871.105-3.066
10-0.0140.558-0.094-1.03
110.0050.037-0.1550.097
Standard thresholds
P-value Threshold
0.001 5.363725
0.0005 6.233605
0.0001 7.503755