MotifIRX5.H12INVIVO.1.SM.D
Gene (human)IRX5
(GeneCards)
Gene synonyms (human)IRX2A, IRXB2
Gene (mouse)Irx5
Gene synonyms (mouse)Irxb2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length8
ConsensusnSWTGTWn
GC content38.75%
Information content (bits; total / per base)7.979 / 0.997
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9539

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.876 0.823 0.824 0.77 0.761 0.717
best 0.964 0.947 0.938 0.91 0.904 0.868
Methyl HT-SELEX, 2 experiments median 0.859 0.803 0.808 0.752 0.761 0.71
best 0.877 0.82 0.826 0.77 0.785 0.73
Non-Methyl HT-SELEX, 4 experiments median 0.911 0.871 0.871 0.826 0.814 0.775
best 0.964 0.947 0.938 0.91 0.904 0.868
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyIRX {3.1.4.1} (TFClass)
TFClass IDTFClass: 3.1.4.1.5
HGNCHGNC:14361
MGIMGI:1859086
EntrezGene (human)GeneID:10265
(SSTAR profile)
EntrezGene (mouse)GeneID:54352
(SSTAR profile)
UniProt ID (human)IRX5_HUMAN
UniProt ID (mouse)IRX5_MOUSE
UniProt AC (human)P78411
(TFClass)
UniProt AC (mouse)Q9JKQ4
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
012297.01682.02703.02857.0
02421.07196.01279.0643.0
035295.020.01004.03220.0
041.06.00.09532.0
050.00.09539.00.0
061.059.00.09479.0
073613.01272.0130.04524.0
083188.02733.01951.01667.0
PFM
ACGT
010.2410.1760.2830.3
020.0440.7540.1340.067
030.5550.0020.1050.338
040.00.0010.00.999
050.00.01.00.0
060.00.0060.00.994
070.3790.1330.0140.474
080.3340.2870.2050.175
PWM
ACGT
01-0.037-0.3490.1250.181
02-1.731.104-0.622-1.308
030.797-4.674-0.8640.3
04-6.587-5.663-6.9491.385
05-6.949-6.9491.386-6.949
06-6.587-3.662-6.9491.379
070.415-0.628-2.8930.64
080.290.136-0.201-0.358
Standard thresholds
P-value Threshold
0.001 5.55407
0.0005 6.271375
0.0001 6.84276