| Motif | IRX5.H12INVIVO.0.M.D |
| Gene (human) | IRX5 (GeneCards) |
| Gene synonyms (human) | IRX2A, IRXB2 |
| Gene (mouse) | Irx5 |
| Gene synonyms (mouse) | Irxb2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | IRX5.H12INVIVO.0.M.D |
| Gene (human) | IRX5 (GeneCards) |
| Gene synonyms (human) | IRX2A, IRXB2 |
| Gene (mouse) | Irx5 |
| Gene synonyms (mouse) | Irxb2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 11 |
| Consensus | nRCGCGTWAvn |
| GC content | 51.47% |
| Information content (bits; total / per base) | 10.69 / 0.972 |
| Data sources | Methyl-HT-SELEX |
| Aligned words | 1393 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.879 | 0.807 | 0.868 | 0.798 | 0.84 | 0.775 |
| best | 0.928 | 0.886 | 0.902 | 0.854 | 0.87 | 0.82 | |
| Methyl HT-SELEX, 2 experiments | median | 0.925 | 0.884 | 0.897 | 0.848 | 0.859 | 0.809 |
| best | 0.928 | 0.886 | 0.902 | 0.854 | 0.87 | 0.82 | |
| Non-Methyl HT-SELEX, 4 experiments | median | 0.829 | 0.75 | 0.803 | 0.732 | 0.757 | 0.701 |
| best | 0.888 | 0.82 | 0.88 | 0.812 | 0.851 | 0.787 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | TALE-type HD {3.1.4} (TFClass) |
| TF subfamily | IRX {3.1.4.1} (TFClass) |
| TFClass ID | TFClass: 3.1.4.1.5 |
| HGNC | HGNC:14361 |
| MGI | MGI:1859086 |
| EntrezGene (human) | GeneID:10265 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:54352 (SSTAR profile) |
| UniProt ID (human) | IRX5_HUMAN |
| UniProt ID (mouse) | IRX5_MOUSE |
| UniProt AC (human) | P78411 (TFClass) |
| UniProt AC (mouse) | Q9JKQ4 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 4 |
| Methyl-HT-SELEX | 2 |
| PCM | IRX5.H12INVIVO.0.M.D.pcm |
| PWM | IRX5.H12INVIVO.0.M.D.pwm |
| PFM | IRX5.H12INVIVO.0.M.D.pfm |
| Alignment | IRX5.H12INVIVO.0.M.D.words.tsv |
| Threshold to P-value map | IRX5.H12INVIVO.0.M.D.thr |
| Motif in other formats | |
| JASPAR format | IRX5.H12INVIVO.0.M.D_jaspar_format.txt |
| MEME format | IRX5.H12INVIVO.0.M.D_meme_format.meme |
| Transfac format | IRX5.H12INVIVO.0.M.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 393.5 | 359.5 | 254.5 | 385.5 |
| 02 | 844.25 | 66.25 | 250.25 | 232.25 |
| 03 | 0.0 | 1332.0 | 0.0 | 61.0 |
| 04 | 433.0 | 0.0 | 942.0 | 18.0 |
| 05 | 0.0 | 1107.0 | 0.0 | 286.0 |
| 06 | 0.0 | 0.0 | 1393.0 | 0.0 |
| 07 | 0.0 | 0.0 | 0.0 | 1393.0 |
| 08 | 725.0 | 40.0 | 0.0 | 628.0 |
| 09 | 999.0 | 363.0 | 31.0 | 0.0 |
| 10 | 327.75 | 691.75 | 265.75 | 107.75 |
| 11 | 359.5 | 339.5 | 451.5 | 242.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.282 | 0.258 | 0.183 | 0.277 |
| 02 | 0.606 | 0.048 | 0.18 | 0.167 |
| 03 | 0.0 | 0.956 | 0.0 | 0.044 |
| 04 | 0.311 | 0.0 | 0.676 | 0.013 |
| 05 | 0.0 | 0.795 | 0.0 | 0.205 |
| 06 | 0.0 | 0.0 | 1.0 | 0.0 |
| 07 | 0.0 | 0.0 | 0.0 | 1.0 |
| 08 | 0.52 | 0.029 | 0.0 | 0.451 |
| 09 | 0.717 | 0.261 | 0.022 | 0.0 |
| 10 | 0.235 | 0.497 | 0.191 | 0.077 |
| 11 | 0.258 | 0.244 | 0.324 | 0.174 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.122 | 0.032 | -0.312 | 0.101 |
| 02 | 0.882 | -1.638 | -0.328 | -0.403 |
| 03 | -5.265 | 1.338 | -5.265 | -1.718 |
| 04 | 0.217 | -5.265 | 0.992 | -2.872 |
| 05 | -5.265 | 1.153 | -5.265 | -0.196 |
| 06 | -5.265 | -5.265 | 1.382 | -5.265 |
| 07 | -5.265 | -5.265 | -5.265 | 1.382 |
| 08 | 0.731 | -2.125 | -5.265 | 0.587 |
| 09 | 1.05 | 0.041 | -2.367 | -5.265 |
| 10 | -0.06 | 0.684 | -0.269 | -1.162 |
| 11 | 0.032 | -0.025 | 0.258 | -0.36 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.638945 |
| 0.0005 | 5.859315 |
| 0.0001 | 7.671225 |