| Motif | IRX5.H12INVITRO.1.SM.B |
| Gene (human) | IRX5 (GeneCards) |
| Gene synonyms (human) | IRX2A, IRXB2 |
| Gene (mouse) | Irx5 |
| Gene synonyms (mouse) | Irxb2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | IRX5.H12INVITRO.1.SM.B |
| Gene (human) | IRX5 (GeneCards) |
| Gene synonyms (human) | IRX2A, IRXB2 |
| Gene (mouse) | Irx5 |
| Gene synonyms (mouse) | Irxb2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 8 |
| Consensus | nSWTGTWn |
| GC content | 38.75% |
| Information content (bits; total / per base) | 7.979 / 0.997 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9539 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.876 | 0.823 | 0.824 | 0.77 | 0.761 | 0.717 |
| best | 0.964 | 0.947 | 0.938 | 0.91 | 0.904 | 0.868 | |
| Methyl HT-SELEX, 2 experiments | median | 0.859 | 0.803 | 0.808 | 0.752 | 0.761 | 0.71 |
| best | 0.877 | 0.82 | 0.826 | 0.77 | 0.785 | 0.73 | |
| Non-Methyl HT-SELEX, 4 experiments | median | 0.911 | 0.871 | 0.871 | 0.826 | 0.814 | 0.775 |
| best | 0.964 | 0.947 | 0.938 | 0.91 | 0.904 | 0.868 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | TALE-type HD {3.1.4} (TFClass) |
| TF subfamily | IRX {3.1.4.1} (TFClass) |
| TFClass ID | TFClass: 3.1.4.1.5 |
| HGNC | HGNC:14361 |
| MGI | MGI:1859086 |
| EntrezGene (human) | GeneID:10265 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:54352 (SSTAR profile) |
| UniProt ID (human) | IRX5_HUMAN |
| UniProt ID (mouse) | IRX5_MOUSE |
| UniProt AC (human) | P78411 (TFClass) |
| UniProt AC (mouse) | Q9JKQ4 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 4 |
| Methyl-HT-SELEX | 2 |
| PCM | IRX5.H12INVITRO.1.SM.B.pcm |
| PWM | IRX5.H12INVITRO.1.SM.B.pwm |
| PFM | IRX5.H12INVITRO.1.SM.B.pfm |
| Alignment | IRX5.H12INVITRO.1.SM.B.words.tsv |
| Threshold to P-value map | IRX5.H12INVITRO.1.SM.B.thr |
| Motif in other formats | |
| JASPAR format | IRX5.H12INVITRO.1.SM.B_jaspar_format.txt |
| MEME format | IRX5.H12INVITRO.1.SM.B_meme_format.meme |
| Transfac format | IRX5.H12INVITRO.1.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2297.0 | 1682.0 | 2703.0 | 2857.0 |
| 02 | 421.0 | 7196.0 | 1279.0 | 643.0 |
| 03 | 5295.0 | 20.0 | 1004.0 | 3220.0 |
| 04 | 1.0 | 6.0 | 0.0 | 9532.0 |
| 05 | 0.0 | 0.0 | 9539.0 | 0.0 |
| 06 | 1.0 | 59.0 | 0.0 | 9479.0 |
| 07 | 3613.0 | 1272.0 | 130.0 | 4524.0 |
| 08 | 3188.0 | 2733.0 | 1951.0 | 1667.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.241 | 0.176 | 0.283 | 0.3 |
| 02 | 0.044 | 0.754 | 0.134 | 0.067 |
| 03 | 0.555 | 0.002 | 0.105 | 0.338 |
| 04 | 0.0 | 0.001 | 0.0 | 0.999 |
| 05 | 0.0 | 0.0 | 1.0 | 0.0 |
| 06 | 0.0 | 0.006 | 0.0 | 0.994 |
| 07 | 0.379 | 0.133 | 0.014 | 0.474 |
| 08 | 0.334 | 0.287 | 0.205 | 0.175 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.037 | -0.349 | 0.125 | 0.181 |
| 02 | -1.73 | 1.104 | -0.622 | -1.308 |
| 03 | 0.797 | -4.674 | -0.864 | 0.3 |
| 04 | -6.587 | -5.663 | -6.949 | 1.385 |
| 05 | -6.949 | -6.949 | 1.386 | -6.949 |
| 06 | -6.587 | -3.662 | -6.949 | 1.379 |
| 07 | 0.415 | -0.628 | -2.893 | 0.64 |
| 08 | 0.29 | 0.136 | -0.201 | -0.358 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.55407 |
| 0.0005 | 6.271375 |
| 0.0001 | 6.84276 |