Motif | IRX5.H12CORE.0.M.C |
Gene (human) | IRX5 (GeneCards) |
Gene synonyms (human) | IRX2A, IRXB2 |
Gene (mouse) | Irx5 |
Gene synonyms (mouse) | Irxb2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | C |
Motif | IRX5.H12CORE.0.M.C |
Gene (human) | IRX5 (GeneCards) |
Gene synonyms (human) | IRX2A, IRXB2 |
Gene (mouse) | Irx5 |
Gene synonyms (mouse) | Irxb2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | C |
Motif length | 11 |
Consensus | nRCGCGTWAvn |
GC content | 51.47% |
Information content (bits; total / per base) | 10.69 / 0.972 |
Data sources | Methyl-HT-SELEX |
Aligned words | 1393 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 6 experiments | median | 0.879 | 0.807 | 0.868 | 0.798 | 0.84 | 0.775 |
best | 0.928 | 0.886 | 0.902 | 0.854 | 0.87 | 0.82 | |
Methyl HT-SELEX, 2 experiments | median | 0.925 | 0.884 | 0.897 | 0.848 | 0.859 | 0.809 |
best | 0.928 | 0.886 | 0.902 | 0.854 | 0.87 | 0.82 | |
Non-Methyl HT-SELEX, 4 experiments | median | 0.829 | 0.75 | 0.803 | 0.732 | 0.757 | 0.701 |
best | 0.888 | 0.82 | 0.88 | 0.812 | 0.851 | 0.787 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | TALE-type HD {3.1.4} (TFClass) |
TF subfamily | IRX {3.1.4.1} (TFClass) |
TFClass ID | TFClass: 3.1.4.1.5 |
HGNC | HGNC:14361 |
MGI | MGI:1859086 |
EntrezGene (human) | GeneID:10265 (SSTAR profile) |
EntrezGene (mouse) | GeneID:54352 (SSTAR profile) |
UniProt ID (human) | IRX5_HUMAN |
UniProt ID (mouse) | IRX5_MOUSE |
UniProt AC (human) | P78411 (TFClass) |
UniProt AC (mouse) | Q9JKQ4 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 4 |
Methyl-HT-SELEX | 2 |
PCM | IRX5.H12CORE.0.M.C.pcm |
PWM | IRX5.H12CORE.0.M.C.pwm |
PFM | IRX5.H12CORE.0.M.C.pfm |
Alignment | IRX5.H12CORE.0.M.C.words.tsv |
Threshold to P-value map | IRX5.H12CORE.0.M.C.thr |
Motif in other formats | |
JASPAR format | IRX5.H12CORE.0.M.C_jaspar_format.txt |
MEME format | IRX5.H12CORE.0.M.C_meme_format.meme |
Transfac format | IRX5.H12CORE.0.M.C_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 393.5 | 359.5 | 254.5 | 385.5 |
02 | 844.25 | 66.25 | 250.25 | 232.25 |
03 | 0.0 | 1332.0 | 0.0 | 61.0 |
04 | 433.0 | 0.0 | 942.0 | 18.0 |
05 | 0.0 | 1107.0 | 0.0 | 286.0 |
06 | 0.0 | 0.0 | 1393.0 | 0.0 |
07 | 0.0 | 0.0 | 0.0 | 1393.0 |
08 | 725.0 | 40.0 | 0.0 | 628.0 |
09 | 999.0 | 363.0 | 31.0 | 0.0 |
10 | 327.75 | 691.75 | 265.75 | 107.75 |
11 | 359.5 | 339.5 | 451.5 | 242.5 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.282 | 0.258 | 0.183 | 0.277 |
02 | 0.606 | 0.048 | 0.18 | 0.167 |
03 | 0.0 | 0.956 | 0.0 | 0.044 |
04 | 0.311 | 0.0 | 0.676 | 0.013 |
05 | 0.0 | 0.795 | 0.0 | 0.205 |
06 | 0.0 | 0.0 | 1.0 | 0.0 |
07 | 0.0 | 0.0 | 0.0 | 1.0 |
08 | 0.52 | 0.029 | 0.0 | 0.451 |
09 | 0.717 | 0.261 | 0.022 | 0.0 |
10 | 0.235 | 0.497 | 0.191 | 0.077 |
11 | 0.258 | 0.244 | 0.324 | 0.174 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.122 | 0.032 | -0.312 | 0.101 |
02 | 0.882 | -1.638 | -0.328 | -0.403 |
03 | -5.265 | 1.338 | -5.265 | -1.718 |
04 | 0.217 | -5.265 | 0.992 | -2.872 |
05 | -5.265 | 1.153 | -5.265 | -0.196 |
06 | -5.265 | -5.265 | 1.382 | -5.265 |
07 | -5.265 | -5.265 | -5.265 | 1.382 |
08 | 0.731 | -2.125 | -5.265 | 0.587 |
09 | 1.05 | 0.041 | -2.367 | -5.265 |
10 | -0.06 | 0.684 | -0.269 | -1.162 |
11 | 0.032 | -0.025 | 0.258 | -0.36 |
P-value | Threshold |
---|---|
0.001 | 4.638945 |
0.0005 | 5.859315 |
0.0001 | 7.671225 |