| Motif | IRX3.H12INVITRO.0.M.C |
| Gene (human) | IRX3 (GeneCards) |
| Gene synonyms (human) | IRXB1 |
| Gene (mouse) | Irx3 |
| Gene synonyms (mouse) | Irxb1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | C |
| Motif | IRX3.H12INVITRO.0.M.C |
| Gene (human) | IRX3 (GeneCards) |
| Gene synonyms (human) | IRXB1 |
| Gene (mouse) | Irx3 |
| Gene synonyms (mouse) | Irxb1 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | C |
| Motif length | 11 |
| Consensus | ndYRCGTAAvn |
| GC content | 47.65% |
| Information content (bits; total / per base) | 10.636 / 0.967 |
| Data sources | Methyl-HT-SELEX |
| Aligned words | 1473 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.674 | 0.608 | 0.66 | 0.601 | 0.624 | 0.584 |
| best | 0.826 | 0.76 | 0.766 | 0.71 | 0.701 | 0.661 | |
| Methyl HT-SELEX, 1 experiments | median | 0.826 | 0.76 | 0.766 | 0.71 | 0.701 | 0.661 |
| best | 0.826 | 0.76 | 0.766 | 0.71 | 0.701 | 0.661 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.627 | 0.569 | 0.612 | 0.565 | 0.577 | 0.551 |
| best | 0.72 | 0.646 | 0.707 | 0.637 | 0.671 | 0.617 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | TALE-type HD {3.1.4} (TFClass) |
| TF subfamily | IRX {3.1.4.1} (TFClass) |
| TFClass ID | TFClass: 3.1.4.1.3 |
| HGNC | HGNC:14360 |
| MGI | MGI:1197522 |
| EntrezGene (human) | GeneID:79191 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:16373 (SSTAR profile) |
| UniProt ID (human) | IRX3_HUMAN |
| UniProt ID (mouse) | IRX3_MOUSE |
| UniProt AC (human) | P78415 (TFClass) |
| UniProt AC (mouse) | P81067 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | IRX3.H12INVITRO.0.M.C.pcm |
| PWM | IRX3.H12INVITRO.0.M.C.pwm |
| PFM | IRX3.H12INVITRO.0.M.C.pfm |
| Alignment | IRX3.H12INVITRO.0.M.C.words.tsv |
| Threshold to P-value map | IRX3.H12INVITRO.0.M.C.thr |
| Motif in other formats | |
| JASPAR format | IRX3.H12INVITRO.0.M.C_jaspar_format.txt |
| MEME format | IRX3.H12INVITRO.0.M.C_meme_format.meme |
| Transfac format | IRX3.H12INVITRO.0.M.C_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 510.5 | 386.5 | 252.5 | 323.5 |
| 02 | 785.5 | 51.5 | 285.5 | 350.5 |
| 03 | 1.0 | 1034.0 | 51.0 | 387.0 |
| 04 | 580.0 | 0.0 | 843.0 | 50.0 |
| 05 | 0.0 | 1362.0 | 0.0 | 111.0 |
| 06 | 0.0 | 0.0 | 1473.0 | 0.0 |
| 07 | 0.0 | 0.0 | 0.0 | 1473.0 |
| 08 | 905.0 | 0.0 | 0.0 | 568.0 |
| 09 | 1321.0 | 145.0 | 7.0 | 0.0 |
| 10 | 340.5 | 702.5 | 228.5 | 201.5 |
| 11 | 345.5 | 404.5 | 494.5 | 228.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.347 | 0.262 | 0.171 | 0.22 |
| 02 | 0.533 | 0.035 | 0.194 | 0.238 |
| 03 | 0.001 | 0.702 | 0.035 | 0.263 |
| 04 | 0.394 | 0.0 | 0.572 | 0.034 |
| 05 | 0.0 | 0.925 | 0.0 | 0.075 |
| 06 | 0.0 | 0.0 | 1.0 | 0.0 |
| 07 | 0.0 | 0.0 | 0.0 | 1.0 |
| 08 | 0.614 | 0.0 | 0.0 | 0.386 |
| 09 | 0.897 | 0.098 | 0.005 | 0.0 |
| 10 | 0.231 | 0.477 | 0.155 | 0.137 |
| 11 | 0.235 | 0.275 | 0.336 | 0.155 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.325 | 0.048 | -0.375 | -0.129 |
| 02 | 0.755 | -1.937 | -0.253 | -0.049 |
| 03 | -4.876 | 1.029 | -1.947 | 0.049 |
| 04 | 0.452 | -5.313 | 0.825 | -1.966 |
| 05 | -5.313 | 1.304 | -5.313 | -1.188 |
| 06 | -5.313 | -5.313 | 1.383 | -5.313 |
| 07 | -5.313 | -5.313 | -5.313 | 1.383 |
| 08 | 0.896 | -5.313 | -5.313 | 0.432 |
| 09 | 1.274 | -0.924 | -3.736 | -5.313 |
| 10 | -0.078 | 0.644 | -0.474 | -0.599 |
| 11 | -0.063 | 0.093 | 0.294 | -0.474 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.713855 |
| 0.0005 | 5.81863 |
| 0.0001 | 7.71757 |