Motif | IRX3.H12CORE.2.S.C |
Gene (human) | IRX3 (GeneCards) |
Gene synonyms (human) | IRXB1 |
Gene (mouse) | Irx3 |
Gene synonyms (mouse) | Irxb1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 2 |
Quality | C |
Motif | IRX3.H12CORE.2.S.C |
Gene (human) | IRX3 (GeneCards) |
Gene synonyms (human) | IRXB1 |
Gene (mouse) | Irx3 |
Gene synonyms (mouse) | Irxb1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 2 |
Quality | C |
Motif length | 21 |
Consensus | ndACAhSnddddWCATGTWvn |
GC content | 35.63% |
Information content (bits; total / per base) | 15.293 / 0.728 |
Data sources | HT-SELEX |
Aligned words | 2422 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.733 | 0.696 | 0.658 | 0.631 | 0.603 | 0.59 |
best | 0.991 | 0.988 | 0.889 | 0.886 | 0.74 | 0.756 | |
Methyl HT-SELEX, 1 experiments | median | 0.746 | 0.7 | 0.682 | 0.644 | 0.63 | 0.605 |
best | 0.746 | 0.7 | 0.682 | 0.644 | 0.63 | 0.605 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.72 | 0.691 | 0.633 | 0.618 | 0.576 | 0.575 |
best | 0.991 | 0.988 | 0.889 | 0.886 | 0.74 | 0.756 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | TALE-type HD {3.1.4} (TFClass) |
TF subfamily | IRX {3.1.4.1} (TFClass) |
TFClass ID | TFClass: 3.1.4.1.3 |
HGNC | HGNC:14360 |
MGI | MGI:1197522 |
EntrezGene (human) | GeneID:79191 (SSTAR profile) |
EntrezGene (mouse) | GeneID:16373 (SSTAR profile) |
UniProt ID (human) | IRX3_HUMAN |
UniProt ID (mouse) | IRX3_MOUSE |
UniProt AC (human) | P78415 (TFClass) |
UniProt AC (mouse) | P81067 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | IRX3.H12CORE.2.S.C.pcm |
PWM | IRX3.H12CORE.2.S.C.pwm |
PFM | IRX3.H12CORE.2.S.C.pfm |
Alignment | IRX3.H12CORE.2.S.C.words.tsv |
Threshold to P-value map | IRX3.H12CORE.2.S.C.thr |
Motif in other formats | |
JASPAR format | IRX3.H12CORE.2.S.C_jaspar_format.txt |
MEME format | IRX3.H12CORE.2.S.C_meme_format.meme |
Transfac format | IRX3.H12CORE.2.S.C_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 494.5 | 418.5 | 664.5 | 844.5 |
02 | 883.5 | 128.5 | 411.5 | 998.5 |
03 | 2027.0 | 167.0 | 103.0 | 125.0 |
04 | 195.0 | 2029.0 | 98.0 | 100.0 |
05 | 2028.0 | 143.0 | 96.0 | 155.0 |
06 | 714.0 | 410.0 | 161.0 | 1137.0 |
07 | 318.0 | 354.0 | 1571.0 | 179.0 |
08 | 897.0 | 483.0 | 584.0 | 458.0 |
09 | 1038.0 | 371.0 | 445.0 | 568.0 |
10 | 1269.0 | 238.0 | 372.0 | 543.0 |
11 | 1143.0 | 255.0 | 331.0 | 693.0 |
12 | 1168.0 | 289.0 | 323.0 | 642.0 |
13 | 1434.0 | 153.0 | 339.0 | 496.0 |
14 | 20.0 | 2164.0 | 113.0 | 125.0 |
15 | 2095.0 | 0.0 | 207.0 | 120.0 |
16 | 1.0 | 2.0 | 3.0 | 2416.0 |
17 | 1.0 | 0.0 | 2421.0 | 0.0 |
18 | 15.0 | 12.0 | 7.0 | 2388.0 |
19 | 1427.0 | 308.0 | 6.0 | 681.0 |
20 | 1173.0 | 677.0 | 354.0 | 218.0 |
21 | 739.75 | 548.75 | 362.75 | 770.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.204 | 0.173 | 0.274 | 0.349 |
02 | 0.365 | 0.053 | 0.17 | 0.412 |
03 | 0.837 | 0.069 | 0.043 | 0.052 |
04 | 0.081 | 0.838 | 0.04 | 0.041 |
05 | 0.837 | 0.059 | 0.04 | 0.064 |
06 | 0.295 | 0.169 | 0.066 | 0.469 |
07 | 0.131 | 0.146 | 0.649 | 0.074 |
08 | 0.37 | 0.199 | 0.241 | 0.189 |
09 | 0.429 | 0.153 | 0.184 | 0.235 |
10 | 0.524 | 0.098 | 0.154 | 0.224 |
11 | 0.472 | 0.105 | 0.137 | 0.286 |
12 | 0.482 | 0.119 | 0.133 | 0.265 |
13 | 0.592 | 0.063 | 0.14 | 0.205 |
14 | 0.008 | 0.893 | 0.047 | 0.052 |
15 | 0.865 | 0.0 | 0.085 | 0.05 |
16 | 0.0 | 0.001 | 0.001 | 0.998 |
17 | 0.0 | 0.0 | 1.0 | 0.0 |
18 | 0.006 | 0.005 | 0.003 | 0.986 |
19 | 0.589 | 0.127 | 0.002 | 0.281 |
20 | 0.484 | 0.28 | 0.146 | 0.09 |
21 | 0.305 | 0.227 | 0.15 | 0.318 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.202 | -0.368 | 0.093 | 0.332 |
02 | 0.377 | -1.538 | -0.385 | 0.499 |
03 | 1.206 | -1.28 | -1.756 | -1.565 |
04 | -1.126 | 1.207 | -1.805 | -1.785 |
05 | 1.206 | -1.433 | -1.825 | -1.353 |
06 | 0.164 | -0.388 | -1.316 | 0.629 |
07 | -0.641 | -0.534 | 0.951 | -1.211 |
08 | 0.392 | -0.225 | -0.036 | -0.278 |
09 | 0.538 | -0.488 | -0.307 | -0.064 |
10 | 0.738 | -0.929 | -0.485 | -0.109 |
11 | 0.634 | -0.86 | -0.601 | 0.135 |
12 | 0.655 | -0.736 | -0.626 | 0.058 |
13 | 0.86 | -1.366 | -0.578 | -0.199 |
14 | -3.321 | 1.271 | -1.665 | -1.565 |
15 | 1.239 | -5.742 | -1.067 | -1.606 |
16 | -5.328 | -5.036 | -4.81 | 1.381 |
17 | -5.328 | -5.742 | 1.383 | -5.742 |
18 | -3.579 | -3.774 | -4.218 | 1.37 |
19 | 0.855 | -0.673 | -4.336 | 0.117 |
20 | 0.66 | 0.111 | -0.534 | -1.016 |
21 | 0.2 | -0.098 | -0.51 | 0.241 |
P-value | Threshold |
---|---|
0.001 | 2.74946 |
0.0005 | 3.99796 |
0.0001 | 6.53026 |