MotifIRX3.H12CORE.2.S.C
Gene (human)IRX3
(GeneCards)
Gene synonyms (human)IRXB1
Gene (mouse)Irx3
Gene synonyms (mouse)Irxb1
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
C
Motif length21
ConsensusndACAhSnddddWCATGTWvn
GC content35.63%
Information content (bits; total / per base)15.293 / 0.728
Data sourcesHT-SELEX
Aligned words2422

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.733 0.696 0.658 0.631 0.603 0.59
best 0.991 0.988 0.889 0.886 0.74 0.756
Methyl HT-SELEX, 1 experiments median 0.746 0.7 0.682 0.644 0.63 0.605
best 0.746 0.7 0.682 0.644 0.63 0.605
Non-Methyl HT-SELEX, 3 experiments median 0.72 0.691 0.633 0.618 0.576 0.575
best 0.991 0.988 0.889 0.886 0.74 0.756
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyIRX {3.1.4.1} (TFClass)
TFClass IDTFClass: 3.1.4.1.3
HGNCHGNC:14360
MGIMGI:1197522
EntrezGene (human)GeneID:79191
(SSTAR profile)
EntrezGene (mouse)GeneID:16373
(SSTAR profile)
UniProt ID (human)IRX3_HUMAN
UniProt ID (mouse)IRX3_MOUSE
UniProt AC (human)P78415
(TFClass)
UniProt AC (mouse)P81067
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01494.5418.5664.5844.5
02883.5128.5411.5998.5
032027.0167.0103.0125.0
04195.02029.098.0100.0
052028.0143.096.0155.0
06714.0410.0161.01137.0
07318.0354.01571.0179.0
08897.0483.0584.0458.0
091038.0371.0445.0568.0
101269.0238.0372.0543.0
111143.0255.0331.0693.0
121168.0289.0323.0642.0
131434.0153.0339.0496.0
1420.02164.0113.0125.0
152095.00.0207.0120.0
161.02.03.02416.0
171.00.02421.00.0
1815.012.07.02388.0
191427.0308.06.0681.0
201173.0677.0354.0218.0
21739.75548.75362.75770.75
PFM
ACGT
010.2040.1730.2740.349
020.3650.0530.170.412
030.8370.0690.0430.052
040.0810.8380.040.041
050.8370.0590.040.064
060.2950.1690.0660.469
070.1310.1460.6490.074
080.370.1990.2410.189
090.4290.1530.1840.235
100.5240.0980.1540.224
110.4720.1050.1370.286
120.4820.1190.1330.265
130.5920.0630.140.205
140.0080.8930.0470.052
150.8650.00.0850.05
160.00.0010.0010.998
170.00.01.00.0
180.0060.0050.0030.986
190.5890.1270.0020.281
200.4840.280.1460.09
210.3050.2270.150.318
PWM
ACGT
01-0.202-0.3680.0930.332
020.377-1.538-0.3850.499
031.206-1.28-1.756-1.565
04-1.1261.207-1.805-1.785
051.206-1.433-1.825-1.353
060.164-0.388-1.3160.629
07-0.641-0.5340.951-1.211
080.392-0.225-0.036-0.278
090.538-0.488-0.307-0.064
100.738-0.929-0.485-0.109
110.634-0.86-0.6010.135
120.655-0.736-0.6260.058
130.86-1.366-0.578-0.199
14-3.3211.271-1.665-1.565
151.239-5.742-1.067-1.606
16-5.328-5.036-4.811.381
17-5.328-5.7421.383-5.742
18-3.579-3.774-4.2181.37
190.855-0.673-4.3360.117
200.660.111-0.534-1.016
210.2-0.098-0.510.241
Standard thresholds
P-value Threshold
0.001 2.74946
0.0005 3.99796
0.0001 6.53026