MotifIRX3.H12CORE.1.S.B
Gene (human)IRX3
(GeneCards)
Gene synonyms (human)IRXB1
Gene (mouse)Irx3
Gene synonyms (mouse)Irxb1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length8
ConsensusnSRTGTWn
GC content38.85%
Information content (bits; total / per base)7.538 / 0.942
Data sourcesHT-SELEX
Aligned words9776

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.76 0.697 0.691 0.647 0.627 0.604
best 0.893 0.849 0.846 0.796 0.752 0.723
Methyl HT-SELEX, 1 experiments median 0.747 0.682 0.692 0.642 0.637 0.606
best 0.747 0.682 0.692 0.642 0.637 0.606
Non-Methyl HT-SELEX, 3 experiments median 0.772 0.712 0.689 0.652 0.617 0.603
best 0.893 0.849 0.846 0.796 0.752 0.723
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyIRX {3.1.4.1} (TFClass)
TFClass IDTFClass: 3.1.4.1.3
HGNCHGNC:14360
MGIMGI:1197522
EntrezGene (human)GeneID:79191
(SSTAR profile)
EntrezGene (mouse)GeneID:16373
(SSTAR profile)
UniProt ID (human)IRX3_HUMAN
UniProt ID (mouse)IRX3_MOUSE
UniProt AC (human)P78415
(TFClass)
UniProt AC (mouse)P81067
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012425.51618.53151.52580.5
02999.756141.751534.751099.75
036038.0113.01849.01776.0
0422.05.063.09686.0
053.04.09757.012.0
069.033.052.09682.0
073916.5755.5160.54943.5
083058.52938.52204.51574.5
PFM
ACGT
010.2480.1660.3220.264
020.1020.6280.1570.112
030.6180.0120.1890.182
040.0020.0010.0060.991
050.00.00.9980.001
060.0010.0030.0050.99
070.4010.0770.0160.506
080.3130.3010.2260.161
PWM
ACGT
01-0.008-0.4120.2540.054
02-0.8930.921-0.465-0.797
030.904-3.055-0.279-0.319
04-4.612-5.815-3.6231.376
05-6.135-5.9621.384-5.142
06-5.378-4.239-3.8081.376
070.471-1.172-2.710.704
080.2240.184-0.103-0.439
Standard thresholds
P-value Threshold
0.001 5.426515
0.0005 5.901095
0.0001 6.858145