| Motif | IRX3.H12CORE.1.S.B |
| Gene (human) | IRX3 (GeneCards) |
| Gene synonyms (human) | IRXB1 |
| Gene (mouse) | Irx3 |
| Gene synonyms (mouse) | Irxb1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | IRX3.H12CORE.1.S.B |
| Gene (human) | IRX3 (GeneCards) |
| Gene synonyms (human) | IRXB1 |
| Gene (mouse) | Irx3 |
| Gene synonyms (mouse) | Irxb1 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 8 |
| Consensus | nSRTGTWn |
| GC content | 38.85% |
| Information content (bits; total / per base) | 7.538 / 0.942 |
| Data sources | HT-SELEX |
| Aligned words | 9776 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.76 | 0.697 | 0.691 | 0.647 | 0.627 | 0.604 |
| best | 0.893 | 0.849 | 0.846 | 0.796 | 0.752 | 0.723 | |
| Methyl HT-SELEX, 1 experiments | median | 0.747 | 0.682 | 0.692 | 0.642 | 0.637 | 0.606 |
| best | 0.747 | 0.682 | 0.692 | 0.642 | 0.637 | 0.606 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.772 | 0.712 | 0.689 | 0.652 | 0.617 | 0.603 |
| best | 0.893 | 0.849 | 0.846 | 0.796 | 0.752 | 0.723 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | TALE-type HD {3.1.4} (TFClass) |
| TF subfamily | IRX {3.1.4.1} (TFClass) |
| TFClass ID | TFClass: 3.1.4.1.3 |
| HGNC | HGNC:14360 |
| MGI | MGI:1197522 |
| EntrezGene (human) | GeneID:79191 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:16373 (SSTAR profile) |
| UniProt ID (human) | IRX3_HUMAN |
| UniProt ID (mouse) | IRX3_MOUSE |
| UniProt AC (human) | P78415 (TFClass) |
| UniProt AC (mouse) | P81067 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | IRX3.H12CORE.1.S.B.pcm |
| PWM | IRX3.H12CORE.1.S.B.pwm |
| PFM | IRX3.H12CORE.1.S.B.pfm |
| Alignment | IRX3.H12CORE.1.S.B.words.tsv |
| Threshold to P-value map | IRX3.H12CORE.1.S.B.thr |
| Motif in other formats | |
| JASPAR format | IRX3.H12CORE.1.S.B_jaspar_format.txt |
| MEME format | IRX3.H12CORE.1.S.B_meme_format.meme |
| Transfac format | IRX3.H12CORE.1.S.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2425.5 | 1618.5 | 3151.5 | 2580.5 |
| 02 | 999.75 | 6141.75 | 1534.75 | 1099.75 |
| 03 | 6038.0 | 113.0 | 1849.0 | 1776.0 |
| 04 | 22.0 | 5.0 | 63.0 | 9686.0 |
| 05 | 3.0 | 4.0 | 9757.0 | 12.0 |
| 06 | 9.0 | 33.0 | 52.0 | 9682.0 |
| 07 | 3916.5 | 755.5 | 160.5 | 4943.5 |
| 08 | 3058.5 | 2938.5 | 2204.5 | 1574.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.248 | 0.166 | 0.322 | 0.264 |
| 02 | 0.102 | 0.628 | 0.157 | 0.112 |
| 03 | 0.618 | 0.012 | 0.189 | 0.182 |
| 04 | 0.002 | 0.001 | 0.006 | 0.991 |
| 05 | 0.0 | 0.0 | 0.998 | 0.001 |
| 06 | 0.001 | 0.003 | 0.005 | 0.99 |
| 07 | 0.401 | 0.077 | 0.016 | 0.506 |
| 08 | 0.313 | 0.301 | 0.226 | 0.161 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.008 | -0.412 | 0.254 | 0.054 |
| 02 | -0.893 | 0.921 | -0.465 | -0.797 |
| 03 | 0.904 | -3.055 | -0.279 | -0.319 |
| 04 | -4.612 | -5.815 | -3.623 | 1.376 |
| 05 | -6.135 | -5.962 | 1.384 | -5.142 |
| 06 | -5.378 | -4.239 | -3.808 | 1.376 |
| 07 | 0.471 | -1.172 | -2.71 | 0.704 |
| 08 | 0.224 | 0.184 | -0.103 | -0.439 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.426515 |
| 0.0005 | 5.901095 |
| 0.0001 | 6.858145 |