MotifIRX3.H12CORE.0.M.C
Gene (human)IRX3
(GeneCards)
Gene synonyms (human)IRXB1
Gene (mouse)Irx3
Gene synonyms (mouse)Irxb1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
C
Motif length11
ConsensusndYRCGTAAvn
GC content47.65%
Information content (bits; total / per base)10.636 / 0.967
Data sourcesMethyl-HT-SELEX
Aligned words1473

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.674 0.608 0.66 0.601 0.624 0.584
best 0.826 0.76 0.766 0.71 0.701 0.661
Methyl HT-SELEX, 1 experiments median 0.826 0.76 0.766 0.71 0.701 0.661
best 0.826 0.76 0.766 0.71 0.701 0.661
Non-Methyl HT-SELEX, 3 experiments median 0.627 0.569 0.612 0.565 0.577 0.551
best 0.72 0.646 0.707 0.637 0.671 0.617
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyIRX {3.1.4.1} (TFClass)
TFClass IDTFClass: 3.1.4.1.3
HGNCHGNC:14360
MGIMGI:1197522
EntrezGene (human)GeneID:79191
(SSTAR profile)
EntrezGene (mouse)GeneID:16373
(SSTAR profile)
UniProt ID (human)IRX3_HUMAN
UniProt ID (mouse)IRX3_MOUSE
UniProt AC (human)P78415
(TFClass)
UniProt AC (mouse)P81067
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01510.5386.5252.5323.5
02785.551.5285.5350.5
031.01034.051.0387.0
04580.00.0843.050.0
050.01362.00.0111.0
060.00.01473.00.0
070.00.00.01473.0
08905.00.00.0568.0
091321.0145.07.00.0
10340.5702.5228.5201.5
11345.5404.5494.5228.5
PFM
ACGT
010.3470.2620.1710.22
020.5330.0350.1940.238
030.0010.7020.0350.263
040.3940.00.5720.034
050.00.9250.00.075
060.00.01.00.0
070.00.00.01.0
080.6140.00.00.386
090.8970.0980.0050.0
100.2310.4770.1550.137
110.2350.2750.3360.155
PWM
ACGT
010.3250.048-0.375-0.129
020.755-1.937-0.253-0.049
03-4.8761.029-1.9470.049
040.452-5.3130.825-1.966
05-5.3131.304-5.313-1.188
06-5.313-5.3131.383-5.313
07-5.313-5.313-5.3131.383
080.896-5.313-5.3130.432
091.274-0.924-3.736-5.313
10-0.0780.644-0.474-0.599
11-0.0630.0930.294-0.474
Standard thresholds
P-value Threshold
0.001 4.713855
0.0005 5.81863
0.0001 7.71757