MotifIRX2.H12INVITRO.0.S.B
Gene (human)IRX2
(GeneCards)
Gene synonyms (human)IRXA2
Gene (mouse)Irx2
Gene synonyms (mouse)Irx6, Irxa2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length10
ConsensusnbWACATGhn
GC content36.79%
Information content (bits; total / per base)11.261 / 1.126
Data sourcesHT-SELEX
Aligned words6682

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.966 0.944 0.948 0.92 0.905 0.875
best 0.978 0.964 0.965 0.945 0.934 0.909
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyTALE-type HD {3.1.4} (TFClass)
TF subfamilyIRX {3.1.4.1} (TFClass)
TFClass IDTFClass: 3.1.4.1.2
HGNCHGNC:14359
MGIMGI:1197526
EntrezGene (human)GeneID:153572
(SSTAR profile)
EntrezGene (mouse)GeneID:16372
(SSTAR profile)
UniProt ID (human)IRX2_HUMAN
UniProt ID (mouse)IRX2_MOUSE
UniProt AC (human)Q9BZI1
(TFClass)
UniProt AC (mouse)P81066
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
012206.251392.251422.251661.25
02511.01161.02086.02924.0
033737.00.0108.02837.0
046682.00.00.00.0
050.06682.00.00.0
066682.00.00.00.0
0763.00.00.06619.0
080.00.06682.00.0
091900.751261.75834.752684.75
101618.51900.51053.52109.5
PFM
ACGT
010.330.2080.2130.249
020.0760.1740.3120.438
030.5590.00.0160.425
041.00.00.00.0
050.01.00.00.0
061.00.00.00.0
070.0090.00.00.991
080.00.01.00.0
090.2840.1890.1250.402
100.2420.2840.1580.316
PWM
ACGT
010.278-0.182-0.161-0.006
02-1.182-0.3630.2220.559
030.804-6.633-2.720.529
041.385-6.633-6.633-6.633
05-6.6331.385-6.633-6.633
061.385-6.633-6.633-6.633
07-3.245-6.633-6.6331.376
08-6.633-6.6331.385-6.633
090.129-0.28-0.6920.474
10-0.0320.129-0.460.233
Standard thresholds
P-value Threshold
0.001 2.50143
0.0005 5.10407
0.0001 8.0233