| Motif | IRF9.H12RSNP.0.PSM.A |
| Gene (human) | IRF9 (GeneCards) |
| Gene synonyms (human) | ISGF3G |
| Gene (mouse) | Irf9 |
| Gene synonyms (mouse) | Isgf3g |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | IRF9.H12RSNP.0.PSM.A |
| Gene (human) | IRF9 (GeneCards) |
| Gene synonyms (human) | ISGF3G |
| Gene (mouse) | Irf9 |
| Gene synonyms (mouse) | Isgf3g |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 20 |
| Consensus | ndWMhCGAAASYGAAASYdh |
| GC content | 40.01% |
| Information content (bits; total / per base) | 17.602 / 0.88 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 535 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 3 (15) | 0.873 | 0.916 | 0.818 | 0.869 | 0.896 | 0.929 | 4.158 | 4.627 | 182.149 | 425.602 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.843 | 0.856 | 0.789 | 0.801 | 0.749 | 0.758 |
| best | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | 0.998 | |
| Methyl HT-SELEX, 1 experiments | median | 1.0 | 0.999 | 0.997 | 0.996 | 0.956 | 0.954 |
| best | 1.0 | 0.999 | 0.997 | 0.996 | 0.956 | 0.954 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.686 | 0.713 | 0.582 | 0.606 | 0.542 | 0.561 |
| best | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | 0.998 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.935 | 0.63 | 0.932 | 0.583 |
| batch 2 | 0.944 | 0.9 | 0.826 | 0.641 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Tryptophan cluster factors {3.5} (TFClass) |
| TF family | IRF {3.5.3} (TFClass) |
| TF subfamily | {3.5.3.0} (TFClass) |
| TFClass ID | TFClass: 3.5.3.0.9 |
| HGNC | HGNC:6131 |
| MGI | MGI:107587 |
| EntrezGene (human) | GeneID:10379 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:16391 (SSTAR profile) |
| UniProt ID (human) | IRF9_HUMAN |
| UniProt ID (mouse) | IRF9_MOUSE |
| UniProt AC (human) | Q00978 (TFClass) |
| UniProt AC (mouse) | Q61179 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 3 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | IRF9.H12RSNP.0.PSM.A.pcm |
| PWM | IRF9.H12RSNP.0.PSM.A.pwm |
| PFM | IRF9.H12RSNP.0.PSM.A.pfm |
| Alignment | IRF9.H12RSNP.0.PSM.A.words.tsv |
| Threshold to P-value map | IRF9.H12RSNP.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | IRF9.H12RSNP.0.PSM.A_jaspar_format.txt |
| MEME format | IRF9.H12RSNP.0.PSM.A_meme_format.meme |
| Transfac format | IRF9.H12RSNP.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 166.0 | 109.0 | 139.0 | 121.0 |
| 02 | 277.5 | 70.5 | 111.5 | 75.5 |
| 03 | 371.0 | 37.0 | 34.0 | 93.0 |
| 04 | 416.0 | 63.0 | 18.0 | 38.0 |
| 05 | 247.0 | 100.0 | 90.0 | 98.0 |
| 06 | 20.0 | 473.0 | 14.0 | 28.0 |
| 07 | 4.0 | 9.0 | 517.0 | 5.0 |
| 08 | 502.0 | 12.0 | 3.0 | 18.0 |
| 09 | 524.0 | 2.0 | 1.0 | 8.0 |
| 10 | 515.0 | 8.0 | 3.0 | 9.0 |
| 11 | 23.0 | 420.0 | 74.0 | 18.0 |
| 12 | 22.0 | 353.0 | 53.0 | 107.0 |
| 13 | 32.0 | 28.0 | 432.0 | 43.0 |
| 14 | 468.0 | 27.0 | 21.0 | 19.0 |
| 15 | 444.0 | 29.0 | 30.0 | 32.0 |
| 16 | 434.0 | 38.0 | 37.0 | 26.0 |
| 17 | 54.0 | 386.0 | 58.0 | 37.0 |
| 18 | 60.0 | 105.0 | 28.0 | 342.0 |
| 19 | 131.5 | 75.5 | 101.5 | 226.5 |
| 20 | 203.25 | 86.25 | 85.25 | 160.25 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.31 | 0.204 | 0.26 | 0.226 |
| 02 | 0.519 | 0.132 | 0.208 | 0.141 |
| 03 | 0.693 | 0.069 | 0.064 | 0.174 |
| 04 | 0.778 | 0.118 | 0.034 | 0.071 |
| 05 | 0.462 | 0.187 | 0.168 | 0.183 |
| 06 | 0.037 | 0.884 | 0.026 | 0.052 |
| 07 | 0.007 | 0.017 | 0.966 | 0.009 |
| 08 | 0.938 | 0.022 | 0.006 | 0.034 |
| 09 | 0.979 | 0.004 | 0.002 | 0.015 |
| 10 | 0.963 | 0.015 | 0.006 | 0.017 |
| 11 | 0.043 | 0.785 | 0.138 | 0.034 |
| 12 | 0.041 | 0.66 | 0.099 | 0.2 |
| 13 | 0.06 | 0.052 | 0.807 | 0.08 |
| 14 | 0.875 | 0.05 | 0.039 | 0.036 |
| 15 | 0.83 | 0.054 | 0.056 | 0.06 |
| 16 | 0.811 | 0.071 | 0.069 | 0.049 |
| 17 | 0.101 | 0.721 | 0.108 | 0.069 |
| 18 | 0.112 | 0.196 | 0.052 | 0.639 |
| 19 | 0.246 | 0.141 | 0.19 | 0.423 |
| 20 | 0.38 | 0.161 | 0.159 | 0.3 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.214 | -0.202 | 0.038 | -0.099 |
| 02 | 0.724 | -0.63 | -0.18 | -0.563 |
| 03 | 1.013 | -1.255 | -1.336 | -0.358 |
| 04 | 1.127 | -0.74 | -1.934 | -1.23 |
| 05 | 0.608 | -0.287 | -0.391 | -0.307 |
| 06 | -1.836 | 1.255 | -2.162 | -1.521 |
| 07 | -3.19 | -2.55 | 1.343 | -3.025 |
| 08 | 1.314 | -2.3 | -3.388 | -1.934 |
| 09 | 1.357 | -3.635 | -3.964 | -2.649 |
| 10 | 1.34 | -2.649 | -3.388 | -2.55 |
| 11 | -1.706 | 1.136 | -0.583 | -1.934 |
| 12 | -1.748 | 0.963 | -0.908 | -0.22 |
| 13 | -1.394 | -1.521 | 1.164 | -1.111 |
| 14 | 1.244 | -1.555 | -1.791 | -1.884 |
| 15 | 1.192 | -1.488 | -1.455 | -1.394 |
| 16 | 1.169 | -1.23 | -1.255 | -1.591 |
| 17 | -0.89 | 1.052 | -0.82 | -1.255 |
| 18 | -0.787 | -0.239 | -1.521 | 0.932 |
| 19 | -0.017 | -0.563 | -0.272 | 0.522 |
| 20 | 0.414 | -0.432 | -0.444 | 0.179 |
| P-value | Threshold |
|---|---|
| 0.001 | 2.39041 |
| 0.0005 | 3.54926 |
| 0.0001 | 6.01141 |