IRF9.H12CORE.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	IRF9.H12CORE.0.PSM.A
Gene (human)	IRF9 (GeneCards)
Gene synonyms (human)	ISGF3G
Gene (mouse)	Irf9
Gene synonyms (mouse)	Isgf3g
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	16
Consensus	nbGAAASTGAAACYnh
GC content	42.39%
Information content (bits; total / per base)	17.307 / 1.082
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	9992

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (15)	0.888	0.933	0.836	0.895	0.897	0.927	4.158	4.573	198.921	453.77

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.846	0.858	0.793	0.804	0.764	0.773
Overall, 4 experiments	best	1.0	1.0	1.0	1.0	0.999	0.999
Methyl HT-SELEX, 1 experiments	median	1.0	1.0	1.0	0.999	0.983	0.983
Methyl HT-SELEX, 1 experiments	best	1.0	1.0	1.0	0.999	0.983	0.983
Non-Methyl HT-SELEX, 3 experiments	median	0.691	0.715	0.587	0.609	0.544	0.563
Non-Methyl HT-SELEX, 3 experiments	best	1.0	1.0	1.0	1.0	0.999	0.999

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.953	0.735	0.941	0.571
batch 2	0.879	0.779	0.886	0.692

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	IRF {3.5.3} (TFClass)
TF subfamily	{3.5.3.0} (TFClass)
TFClass ID	TFClass: 3.5.3.0.9
HGNC	HGNC:6131
MGI	MGI:107587
EntrezGene (human)	GeneID:10379 (SSTAR profile)
EntrezGene (mouse)	GeneID:16391 (SSTAR profile)
UniProt ID (human)	IRF9_HUMAN
UniProt ID (mouse)	IRF9_MOUSE
UniProt AC (human)	Q00978 (TFClass)
UniProt AC (mouse)	Q61179 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	IRF9.H12CORE.0.PSM.A.pcm
PWM	IRF9.H12CORE.0.PSM.A.pwm
PFM	IRF9.H12CORE.0.PSM.A.pfm
Alignment	IRF9.H12CORE.0.PSM.A.words.tsv
Threshold to P-value map	IRF9.H12CORE.0.PSM.A.thr
Motif in other formats
JASPAR format	IRF9.H12CORE.0.PSM.A_jaspar_format.txt
MEME format	IRF9.H12CORE.0.PSM.A_meme_format.meme
Transfac format	IRF9.H12CORE.0.PSM.A_transfac_format.txt
Homer format	IRF9.H12CORE.0.PSM.A_homer_format_0.001.txt IRF9.H12CORE.0.PSM.A_homer_format_0.0005.txt IRF9.H12CORE.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2285.5	2614.5	3134.5	1957.5
02	817.0	4422.0	1526.0	3227.0
03	428.0	204.0	9174.0	186.0
04	9265.0	246.0	288.0	193.0
05	9338.0	70.0	177.0	407.0
06	9729.0	84.0	49.0	130.0
07	148.0	6205.0	3581.0	58.0
08	56.0	3237.0	38.0	6661.0
09	82.0	3.0	9881.0	26.0
10	9774.0	136.0	38.0	44.0
11	9269.0	30.0	123.0	570.0
12	9709.0	130.0	45.0	108.0
13	122.0	7210.0	2553.0	107.0
14	633.0	3399.0	408.0	5552.0
15	2609.75	1577.75	3473.75	2330.75
16	4304.5	1905.5	1808.5	1973.5

PFM

	A	C	G	T
01	0.229	0.262	0.314	0.196
02	0.082	0.443	0.153	0.323
03	0.043	0.02	0.918	0.019
04	0.927	0.025	0.029	0.019
05	0.935	0.007	0.018	0.041
06	0.974	0.008	0.005	0.013
07	0.015	0.621	0.358	0.006
08	0.006	0.324	0.004	0.667
09	0.008	0.0	0.989	0.003
10	0.978	0.014	0.004	0.004
11	0.928	0.003	0.012	0.057
12	0.972	0.013	0.005	0.011
13	0.012	0.722	0.256	0.011
14	0.063	0.34	0.041	0.556
15	0.261	0.158	0.348	0.233
16	0.431	0.191	0.181	0.198

PWM

	A	C	G	T
01	-0.089	0.046	0.227	-0.244
02	-1.116	0.571	-0.492	0.256
03	-1.76	-2.495	1.3	-2.586
04	1.31	-2.31	-2.153	-2.55
05	1.318	-3.543	-2.635	-1.81
06	1.359	-3.366	-3.886	-2.939
07	-2.812	0.909	0.36	-3.725
08	-3.759	0.259	-4.128	0.98
09	-3.39	-6.156	1.374	-4.481
10	1.364	-2.895	-4.128	-3.989
11	1.311	-4.349	-2.993	-1.474
12	1.357	-2.939	-3.968	-3.121
13	-3.001	1.059	0.022	-3.13
14	-1.37	0.308	-1.807	0.798
15	0.044	-0.459	0.329	-0.069
16	0.544	-0.27	-0.323	-0.235

Standard thresholds

P-value	Threshold
0.001	1.14731
0.0005	2.53041
0.0001	5.49596