MotifIRF7.H12INVIVO.1.SM.D
Gene (human)IRF7
(GeneCards)
Gene synonyms (human)
Gene (mouse)Irf7
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length19
ConsensusnvWWnCGAAAvYSRWWnhn
GC content40.99%
Information content (bits; total / per base)14.693 / 0.773
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8950

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.804 0.792 0.662 0.67 0.579 0.6
best 0.918 0.909 0.736 0.749 0.607 0.643
Methyl HT-SELEX, 1 experiments median 0.613 0.614 0.543 0.556 0.514 0.529
best 0.613 0.614 0.543 0.556 0.514 0.529
Non-Methyl HT-SELEX, 3 experiments median 0.91 0.897 0.725 0.738 0.607 0.639
best 0.918 0.909 0.736 0.749 0.607 0.643

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.856 0.188 0.828 0.552
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyIRF {3.5.3} (TFClass)
TF subfamily {3.5.3.0} (TFClass)
TFClass IDTFClass: 3.5.3.0.7
HGNCHGNC:6122
MGIMGI:1859212
EntrezGene (human)GeneID:3665
(SSTAR profile)
EntrezGene (mouse)GeneID:54123
(SSTAR profile)
UniProt ID (human)IRF7_HUMAN
UniProt ID (mouse)IRF7_MOUSE
UniProt AC (human)Q92985
(TFClass)
UniProt AC (mouse)P70434
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011530.753358.752199.751860.75
024173.51424.52574.5777.5
036237.0506.0735.01472.0
046351.0969.0296.01334.0
052554.02783.01446.02167.0
06139.08148.0161.0502.0
0726.031.08849.044.0
088887.052.03.08.0
098910.024.06.010.0
108754.027.00.0169.0
112659.02366.03238.0687.0
12222.05187.0222.03319.0
13598.01807.05881.0664.0
145809.0477.01966.0698.0
156805.0643.0511.0991.0
166411.0792.0401.01346.0
172499.02237.02325.01889.0
181279.752749.751062.753857.75
192305.01914.02326.02405.0
PFM
ACGT
010.1710.3750.2460.208
020.4660.1590.2880.087
030.6970.0570.0820.164
040.710.1080.0330.149
050.2850.3110.1620.242
060.0160.910.0180.056
070.0030.0030.9890.005
080.9930.0060.00.001
090.9960.0030.0010.001
100.9780.0030.00.019
110.2970.2640.3620.077
120.0250.580.0250.371
130.0670.2020.6570.074
140.6490.0530.220.078
150.760.0720.0570.111
160.7160.0880.0450.15
170.2790.250.260.211
180.1430.3070.1190.431
190.2580.2140.260.269
PWM
ACGT
01-0.3790.406-0.017-0.184
020.623-0.4510.14-1.055
031.024-1.483-1.111-0.418
041.043-0.836-2.016-0.516
050.1320.218-0.436-0.032
06-2.7631.292-2.619-1.491
07-4.372-4.2091.374-3.88
081.378-3.72-6.051-5.384
091.381-4.446-5.601-5.207
101.363-4.337-6.892-2.571
110.1720.0560.369-1.178
12-2.3010.84-2.3010.394
13-1.317-0.2130.966-1.212
140.953-1.542-0.129-1.163
151.112-1.244-1.473-0.813
161.052-1.037-1.715-0.508
170.11-0.00.038-0.169
18-0.5580.206-0.7430.544
190.03-0.1560.0390.072
Standard thresholds
P-value Threshold
0.001 2.78976
0.0005 4.07011
0.0001 6.66021