MotifIRF7.H12INVIVO.0.S.D
Gene (human)IRF7
(GeneCards)
Gene synonyms (human)
Gene (mouse)Irf7
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length14
ConsensusnbRAAnCGAAAdYv
GC content38.27%
Information content (bits; total / per base)13.992 / 0.999
Data sourcesHT-SELEX
Aligned words7780

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.827 0.826 0.655 0.687 0.561 0.602
best 0.957 0.955 0.76 0.768 0.62 0.656
Methyl HT-SELEX, 1 experiments median 0.612 0.595 0.55 0.551 0.516 0.527
best 0.612 0.595 0.55 0.551 0.516 0.527
Non-Methyl HT-SELEX, 3 experiments median 0.938 0.922 0.729 0.762 0.595 0.646
best 0.957 0.955 0.76 0.768 0.62 0.656

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.774 0.21 0.779 0.567
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyIRF {3.5.3} (TFClass)
TF subfamily {3.5.3.0} (TFClass)
TFClass IDTFClass: 3.5.3.0.7
HGNCHGNC:6122
MGIMGI:1859212
EntrezGene (human)GeneID:3665
(SSTAR profile)
EntrezGene (mouse)GeneID:54123
(SSTAR profile)
UniProt ID (human)IRF7_HUMAN
UniProt ID (mouse)IRF7_MOUSE
UniProt AC (human)Q92985
(TFClass)
UniProt AC (mouse)P70434
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012122.752486.751865.751304.75
02594.254456.25977.251752.25
034782.0658.02025.0315.0
047103.0156.0148.0373.0
057117.0300.065.0298.0
062592.02370.01101.01717.0
0762.07628.054.036.0
080.00.07780.00.0
097773.06.00.01.0
107393.04.042.0341.0
116831.039.037.0873.0
123347.01057.01323.02053.0
13288.751702.75328.755459.75
141739.253491.251586.25963.25
PFM
ACGT
010.2730.320.240.168
020.0760.5730.1260.225
030.6150.0850.260.04
040.9130.020.0190.048
050.9150.0390.0080.038
060.3330.3050.1420.221
070.0080.980.0070.005
080.00.01.00.0
090.9990.0010.00.0
100.950.0010.0050.044
110.8780.0050.0050.112
120.430.1360.170.264
130.0370.2190.0420.702
140.2240.4490.2040.124
PWM
ACGT
010.0870.245-0.042-0.399
02-1.1830.828-0.687-0.104
030.899-1.0820.04-1.815
041.294-2.51-2.562-1.647
051.296-1.863-3.366-1.87
060.2870.197-0.568-0.125
07-3.4121.366-3.545-3.93
08-6.768-6.7681.385-6.768
091.385-5.465-6.768-6.399
101.334-5.743-3.785-1.736
111.255-3.855-3.904-0.8
120.542-0.609-0.3850.054
13-1.901-0.133-1.7721.031
14-0.1120.584-0.204-0.702
Standard thresholds
P-value Threshold
0.001 2.85881
0.0005 4.18236
0.0001 6.81641