IRF7.H12INVITRO.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	IRF7.H12INVITRO.0.S.B
Gene (human)	IRF7 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Irf7
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	nbvRMnCGAAAnbn
GC content	44.07%
Information content (bits; total / per base)	10.966 / 0.783
Data sources	HT-SELEX
Aligned words	2258

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.823	0.82	0.664	0.686	0.575	0.606
Overall, 4 experiments	best	0.943	0.94	0.763	0.767	0.63	0.659
Methyl HT-SELEX, 1 experiments	median	0.613	0.593	0.551	0.551	0.517	0.527
Methyl HT-SELEX, 1 experiments	best	0.613	0.593	0.551	0.551	0.517	0.527
Non-Methyl HT-SELEX, 3 experiments	median	0.931	0.917	0.735	0.758	0.609	0.649
Non-Methyl HT-SELEX, 3 experiments	best	0.943	0.94	0.763	0.767	0.63	0.659

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.797	0.167	0.713	0.507

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	IRF {3.5.3} (TFClass)
TF subfamily	{3.5.3.0} (TFClass)
TFClass ID	TFClass: 3.5.3.0.7
HGNC	HGNC:6122
MGI	MGI:1859212
EntrezGene (human)	GeneID:3665 (SSTAR profile)
EntrezGene (mouse)	GeneID:54123 (SSTAR profile)
UniProt ID (human)	IRF7_HUMAN
UniProt ID (mouse)	IRF7_MOUSE
UniProt AC (human)	Q92985 (TFClass)
UniProt AC (mouse)	P70434 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	IRF7.H12INVITRO.0.S.B.pcm
PWM	IRF7.H12INVITRO.0.S.B.pwm
PFM	IRF7.H12INVITRO.0.S.B.pfm
Alignment	IRF7.H12INVITRO.0.S.B.words.tsv
Threshold to P-value map	IRF7.H12INVITRO.0.S.B.thr
Motif in other formats
JASPAR format	IRF7.H12INVITRO.0.S.B_jaspar_format.txt
MEME format	IRF7.H12INVITRO.0.S.B_meme_format.meme
Transfac format	IRF7.H12INVITRO.0.S.B_transfac_format.txt
Homer format	IRF7.H12INVITRO.0.S.B_homer_format_0.001.txt IRF7.H12INVITRO.0.S.B_homer_format_0.0005.txt IRF7.H12INVITRO.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	575.5	780.5	551.5	350.5
02	335.5	940.5	529.5	452.5
03	1008.0	393.0	628.0	229.0
04	1558.0	198.0	266.0	236.0
05	1534.0	469.0	68.0	187.0
06	672.0	630.0	656.0	300.0
07	4.0	2173.0	37.0	44.0
08	0.0	2.0	2252.0	4.0
09	2244.0	8.0	0.0	6.0
10	2193.0	0.0	56.0	9.0
11	2058.0	35.0	48.0	117.0
12	848.0	521.0	450.0	439.0
13	217.75	593.75	321.75	1124.75
14	517.25	740.25	584.25	416.25

PFM

	A	C	G	T
01	0.255	0.346	0.244	0.155
02	0.149	0.417	0.234	0.2
03	0.446	0.174	0.278	0.101
04	0.69	0.088	0.118	0.105
05	0.679	0.208	0.03	0.083
06	0.298	0.279	0.291	0.133
07	0.002	0.962	0.016	0.019
08	0.0	0.001	0.997	0.002
09	0.994	0.004	0.0	0.003
10	0.971	0.0	0.025	0.004
11	0.911	0.016	0.021	0.052
12	0.376	0.231	0.199	0.194
13	0.096	0.263	0.142	0.498
14	0.229	0.328	0.259	0.184

PWM

	A	C	G	T
01	0.019	0.323	-0.023	-0.475
02	-0.518	0.509	-0.064	-0.22
03	0.578	-0.361	0.106	-0.897
04	1.013	-1.041	-0.749	-0.867
05	0.998	-0.185	-2.092	-1.098
06	0.174	0.109	0.15	-0.629
07	-4.559	1.345	-2.678	-2.512
08	-5.682	-4.971	1.381	-4.559
09	1.378	-4.044	-5.682	-4.269
10	1.355	-5.682	-2.28	-3.948
11	1.291	-2.73	-2.429	-1.561
12	0.406	-0.08	-0.226	-0.25
13	-0.947	0.05	-0.56	0.688
14	-0.087	0.27	0.034	-0.303

Standard thresholds

P-value	Threshold
0.001	4.42556
0.0005	5.51486
0.0001	7.51126