MotifIRF6.H12INVITRO.0.SM.B
Gene (human)IRF6
(GeneCards)
Gene synonyms (human)
Gene (mouse)Irf6
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusnvYCGAAACYn
GC content49.6%
Information content (bits; total / per base)12.741 / 1.158
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8044

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.969 0.949 0.919 0.899 0.763 0.772
best 0.972 0.958 0.927 0.902 0.784 0.787
Methyl HT-SELEX, 1 experiments median 0.969 0.949 0.927 0.902 0.784 0.787
best 0.969 0.949 0.927 0.902 0.784 0.787
Non-Methyl HT-SELEX, 2 experiments median 0.831 0.815 0.75 0.745 0.653 0.663
best 0.972 0.958 0.919 0.899 0.763 0.772

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.724 0.249 0.442 0.249
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyIRF {3.5.3} (TFClass)
TF subfamily {3.5.3.0} (TFClass)
TFClass IDTFClass: 3.5.3.0.6
HGNCHGNC:6121
MGIMGI:1859211
EntrezGene (human)GeneID:3664
(SSTAR profile)
EntrezGene (mouse)GeneID:54139
(SSTAR profile)
UniProt ID (human)IRF6_HUMAN
UniProt ID (mouse)IRF6_MOUSE
UniProt AC (human)O14896
(TFClass)
UniProt AC (mouse)P97431
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
PCM
ACGT
012674.02213.01208.01949.0
024600.751487.751129.75825.75
03738.05091.0875.01340.0
0417.07973.00.054.0
050.00.08044.00.0
068044.00.00.00.0
075572.00.00.02472.0
088044.00.00.00.0
090.08044.00.00.0
10146.03112.0197.04589.0
112234.251894.252621.251294.25
PFM
ACGT
010.3320.2750.150.242
020.5720.1850.140.103
030.0920.6330.1090.167
040.0020.9910.00.007
050.00.01.00.0
061.00.00.00.0
070.6930.00.00.307
081.00.00.00.0
090.01.00.00.0
100.0180.3870.0240.57
110.2780.2350.3260.161
PWM
ACGT
010.2850.096-0.509-0.031
020.827-0.301-0.576-0.888
03-1.0010.928-0.831-0.405
04-4.651.377-6.797-3.578
05-6.797-6.7971.385-6.797
061.385-6.797-6.797-6.797
071.018-6.797-6.7970.206
081.385-6.797-6.797-6.797
09-6.7971.385-6.797-6.797
10-2.6090.436-2.3130.824
110.105-0.060.265-0.44
Standard thresholds
P-value Threshold
0.001 1.41929
0.0005 3.47814
0.0001 7.73743