MotifIRF5.H12INVIVO.0.SM.B
Gene (human)IRF5
(GeneCards)
Gene synonyms (human)
Gene (mouse)Irf5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length17
ConsensusvnhKWWASCGAAACYvn
GC content47.13%
Information content (bits; total / per base)15.054 / 0.886
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9841

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 4 (26) 0.754 0.811 0.619 0.698 0.745 0.799 2.203 2.492 55.879 91.319

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.994 0.991 0.979 0.972 0.896 0.896
best 0.999 0.999 0.997 0.996 0.987 0.983
Methyl HT-SELEX, 2 experiments median 0.995 0.993 0.981 0.975 0.896 0.896
best 0.999 0.998 0.991 0.989 0.929 0.927
Non-Methyl HT-SELEX, 4 experiments median 0.792 0.793 0.759 0.763 0.732 0.735
best 0.999 0.999 0.997 0.996 0.987 0.983

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.582 0.218 0.462 0.308
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyIRF {3.5.3} (TFClass)
TF subfamily {3.5.3.0} (TFClass)
TFClass IDTFClass: 3.5.3.0.5
HGNCHGNC:6120
MGIMGI:1350924
EntrezGene (human)GeneID:3663
(SSTAR profile)
EntrezGene (mouse)GeneID:27056
(SSTAR profile)
UniProt ID (human)IRF5_HUMAN
UniProt ID (mouse)IRF5_MOUSE
UniProt AC (human)Q13568
(TFClass)
UniProt AC (mouse)P56477
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 4 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
014010.02360.02323.01148.0
021894.53106.53016.51823.5
031055.04739.0874.03173.0
041062.01036.06294.01449.0
056720.01086.0792.01243.0
066141.01194.0919.01587.0
078541.0407.0654.0239.0
08481.07367.01654.0339.0
09149.07981.06.01705.0
10105.03.09728.05.0
119812.012.015.02.0
128526.02.0166.01147.0
139826.06.02.07.0
1458.09153.0590.040.0
15538.03987.0264.05052.0
163883.251297.253557.251103.25
173886.52096.52156.51701.5
PFM
ACGT
010.4070.240.2360.117
020.1930.3160.3070.185
030.1070.4820.0890.322
040.1080.1050.640.147
050.6830.110.080.126
060.6240.1210.0930.161
070.8680.0410.0660.024
080.0490.7490.1680.034
090.0150.8110.0010.173
100.0110.00.9890.001
110.9970.0010.0020.0
120.8660.00.0170.117
130.9980.0010.00.001
140.0060.930.060.004
150.0550.4050.0270.513
160.3950.1320.3610.112
170.3950.2130.2190.173
PWM
ACGT
010.488-0.042-0.057-0.761
02-0.2610.2330.204-0.299
03-0.8450.655-1.0330.254
04-0.839-0.8640.939-0.529
051.004-0.817-1.131-0.682
060.914-0.722-0.983-0.438
071.244-1.795-1.322-2.323
08-1.6281.096-0.397-1.976
09-2.791.176-5.693-0.366
10-3.133-6.1421.374-5.821
111.383-5.149-4.958-6.351
121.242-6.351-2.683-0.762
131.384-5.693-6.351-5.579
14-3.711.313-1.425-4.064
15-1.5170.482-2.2240.719
160.456-0.6390.368-0.801
170.457-0.16-0.132-0.368
Standard thresholds
P-value Threshold
0.001 2.44266
0.0005 3.81496
0.0001 6.54951