MotifIRF4.H12INVIVO.1.S.B
Gene (human)IRF4
(GeneCards)
Gene synonyms (human)MUM1
Gene (mouse)Irf4
Gene synonyms (mouse)Spip
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length14
ConsensusnvvhWMYGAAAChn
GC content48.24%
Information content (bits; total / per base)10.487 / 0.749
Data sourcesHT-SELEX
Aligned words8047

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 8 (53) 0.723 0.896 0.609 0.857 0.711 0.872 2.094 3.651 61.553 236.06
Mouse 14 (85) 0.764 0.835 0.665 0.759 0.743 0.821 2.396 2.985 104.538 407.018

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.93 0.926 0.829 0.836 0.759 0.77
best 0.998 0.996 0.995 0.992 0.986 0.98
Methyl HT-SELEX, 1 experiments median 0.992 0.987 0.98 0.971 0.941 0.927
best 0.992 0.987 0.98 0.971 0.941 0.927
Non-Methyl HT-SELEX, 3 experiments median 0.868 0.865 0.678 0.702 0.577 0.613
best 0.998 0.996 0.995 0.992 0.986 0.98

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.953 0.879 0.843 0.606
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyIRF {3.5.3} (TFClass)
TF subfamily {3.5.3.0} (TFClass)
TFClass IDTFClass: 3.5.3.0.4
HGNCHGNC:6119
MGIMGI:1096873
EntrezGene (human)GeneID:3662
(SSTAR profile)
EntrezGene (mouse)GeneID:16364
(SSTAR profile)
UniProt ID (human)IRF4_HUMAN
UniProt ID (mouse)IRF4_MOUSE
UniProt AC (human)Q15306
(TFClass)
UniProt AC (mouse)Q64287
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 8 human, 14 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011535.53071.51912.51527.5
021509.51797.53792.5947.5
033431.01712.01980.0924.0
044264.01362.0924.01497.0
055365.0970.0532.01180.0
061109.04906.0988.01044.0
07288.06107.0295.01357.0
0855.0120.07820.052.0
097824.0129.057.037.0
107485.056.0108.0398.0
117357.0335.0160.0195.0
12429.06491.0786.0341.0
13912.53435.5587.53111.5
142634.52145.51761.51505.5
PFM
ACGT
010.1910.3820.2380.19
020.1880.2230.4710.118
030.4260.2130.2460.115
040.530.1690.1150.186
050.6670.1210.0660.147
060.1380.610.1230.13
070.0360.7590.0370.169
080.0070.0150.9720.006
090.9720.0160.0070.005
100.930.0070.0130.049
110.9140.0420.020.024
120.0530.8070.0980.042
130.1130.4270.0730.387
140.3270.2670.2190.187
PWM
ACGT
01-0.270.423-0.051-0.275
02-0.287-0.1120.633-0.752
030.533-0.161-0.016-0.777
040.751-0.39-0.777-0.295
050.98-0.728-1.327-0.533
06-0.5950.891-0.71-0.655
07-1.9371.11-1.913-0.393
08-3.56-2.8021.357-3.614
091.357-2.731-3.526-3.938
101.313-3.543-2.905-1.616
111.296-1.787-2.519-2.323
12-1.5411.171-0.938-1.769
13-0.7890.535-1.2280.436
140.2690.064-0.133-0.29
Standard thresholds
P-value Threshold
0.001 4.58831
0.0005 5.47986
0.0001 7.28921