MotifIRF4.H12CORE.0.P.B
Gene (human)IRF4
(GeneCards)
Gene synonyms (human)MUM1
Gene (mouse)Irf4
Gene synonyms (mouse)Spip
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length17
ConsensusdddndGRAAvWGAAASh
GC content41.34%
Information content (bits; total / per base)12.766 / 0.751
Data sourcesChIP-Seq
Aligned words985

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 8 (53) 0.733 0.877 0.666 0.851 0.81 0.913 3.477 5.166 77.796 286.398
Mouse 14 (85) 0.794 0.934 0.746 0.917 0.861 0.957 4.295 6.23 148.409 663.276

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.857 0.853 0.778 0.78 0.709 0.713
best 0.988 0.983 0.965 0.952 0.909 0.891
Methyl HT-SELEX, 1 experiments median 0.988 0.983 0.956 0.943 0.876 0.861
best 0.988 0.983 0.956 0.943 0.876 0.861
Non-Methyl HT-SELEX, 3 experiments median 0.725 0.724 0.6 0.617 0.543 0.565
best 0.988 0.981 0.965 0.952 0.909 0.891

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.627 0.476 0.737 0.644
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classTryptophan cluster factors {3.5} (TFClass)
TF familyIRF {3.5.3} (TFClass)
TF subfamily {3.5.3.0} (TFClass)
TFClass IDTFClass: 3.5.3.0.4
HGNCHGNC:6119
MGIMGI:1096873
EntrezGene (human)GeneID:3662
(SSTAR profile)
EntrezGene (mouse)GeneID:16364
(SSTAR profile)
UniProt ID (human)IRF4_HUMAN
UniProt ID (mouse)IRF4_MOUSE
UniProt AC (human)Q15306
(TFClass)
UniProt AC (mouse)Q64287
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 8 human, 14 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01439.0171.0201.0174.0
02505.0107.0199.0174.0
03490.0102.0215.0178.0
04257.0236.0338.0154.0
05420.0158.0193.0214.0
06196.014.0764.011.0
07375.025.0574.011.0
08889.015.065.016.0
09866.026.044.049.0
10137.0476.0318.054.0
11130.0122.034.0699.0
1233.04.0941.07.0
13855.013.0111.06.0
14794.029.0152.010.0
15910.06.047.022.0
16141.0512.0305.027.0
17154.0313.093.0425.0
PFM
ACGT
010.4460.1740.2040.177
020.5130.1090.2020.177
030.4970.1040.2180.181
040.2610.240.3430.156
050.4260.160.1960.217
060.1990.0140.7760.011
070.3810.0250.5830.011
080.9030.0150.0660.016
090.8790.0260.0450.05
100.1390.4830.3230.055
110.1320.1240.0350.71
120.0340.0040.9550.007
130.8680.0130.1130.006
140.8060.0290.1540.01
150.9240.0060.0480.022
160.1430.520.310.027
170.1560.3180.0940.431
PWM
ACGT
010.575-0.362-0.201-0.344
020.715-0.825-0.211-0.344
030.685-0.872-0.135-0.322
040.042-0.0420.315-0.465
050.531-0.44-0.242-0.139
06-0.226-2.7581.128-2.97
070.418-2.2280.842-2.97
081.279-2.697-1.313-2.638
091.253-2.191-1.691-1.587
10-0.5810.6560.254-1.493
11-0.633-0.695-1.9381.039
12-1.966-3.7691.335-3.347
131.24-2.824-0.788-3.469
141.166-2.088-0.478-3.052
151.302-3.469-1.627-2.347
16-0.5520.7280.213-2.156
17-0.4650.238-0.9620.543
Standard thresholds
P-value Threshold
0.001 3.96471
0.0005 4.96026
0.0001 7.02996