| Motif | IRF2.H12INVITRO.0.PSM.A |
| Gene (human) | IRF2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Irf2 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | IRF2.H12INVITRO.0.PSM.A |
| Gene (human) | IRF2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Irf2 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 19 |
| Consensus | nvhWnYGAAAGYGAAASbd |
| GC content | 45.2% |
| Information content (bits; total / per base) | 17.761 / 0.935 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 1876 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 5 (30) | 0.907 | 0.967 | 0.894 | 0.968 | 0.926 | 0.963 | 5.836 | 7.882 | 265.907 | 636.921 |
| Mouse | 4 (24) | 0.794 | 0.961 | 0.782 | 0.952 | 0.791 | 0.95 | 4.633 | 5.32 | 82.577 | 298.155 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.999 | 0.998 | 0.996 | 0.994 | 0.977 | 0.973 |
| best | 0.999 | 0.999 | 0.996 | 0.995 | 0.984 | 0.979 | |
| Methyl HT-SELEX, 1 experiments | median | 0.999 | 0.999 | 0.996 | 0.995 | 0.971 | 0.967 |
| best | 0.999 | 0.999 | 0.996 | 0.995 | 0.971 | 0.967 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.998 | 0.997 | 0.995 | 0.993 | 0.984 | 0.979 |
| best | 0.998 | 0.997 | 0.995 | 0.993 | 0.984 | 0.979 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.852 | 0.719 | 0.844 | 0.714 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Tryptophan cluster factors {3.5} (TFClass) |
| TF family | IRF {3.5.3} (TFClass) |
| TF subfamily | {3.5.3.0} (TFClass) |
| TFClass ID | TFClass: 3.5.3.0.2 |
| HGNC | HGNC:6117 |
| MGI | MGI:96591 |
| EntrezGene (human) | GeneID:3660 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:16363 (SSTAR profile) |
| UniProt ID (human) | IRF2_HUMAN |
| UniProt ID (mouse) | IRF2_MOUSE |
| UniProt AC (human) | P14316 (TFClass) |
| UniProt AC (mouse) | P23906 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 5 human, 4 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | IRF2.H12INVITRO.0.PSM.A.pcm |
| PWM | IRF2.H12INVITRO.0.PSM.A.pwm |
| PFM | IRF2.H12INVITRO.0.PSM.A.pfm |
| Alignment | IRF2.H12INVITRO.0.PSM.A.words.tsv |
| Threshold to P-value map | IRF2.H12INVITRO.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | IRF2.H12INVITRO.0.PSM.A_jaspar_format.txt |
| MEME format | IRF2.H12INVITRO.0.PSM.A_meme_format.meme |
| Transfac format | IRF2.H12INVITRO.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 354.5 | 507.5 | 694.5 | 319.5 |
| 02 | 755.0 | 378.0 | 551.0 | 192.0 |
| 03 | 855.0 | 229.0 | 223.0 | 569.0 |
| 04 | 1339.0 | 124.0 | 129.0 | 284.0 |
| 05 | 350.0 | 410.0 | 715.0 | 401.0 |
| 06 | 21.0 | 1387.0 | 73.0 | 395.0 |
| 07 | 11.0 | 7.0 | 1857.0 | 1.0 |
| 08 | 1860.0 | 5.0 | 10.0 | 1.0 |
| 09 | 1805.0 | 1.0 | 2.0 | 68.0 |
| 10 | 1874.0 | 0.0 | 0.0 | 2.0 |
| 11 | 12.0 | 562.0 | 1293.0 | 9.0 |
| 12 | 15.0 | 1034.0 | 43.0 | 784.0 |
| 13 | 47.0 | 5.0 | 1820.0 | 4.0 |
| 14 | 1664.0 | 66.0 | 96.0 | 50.0 |
| 15 | 1547.0 | 50.0 | 39.0 | 240.0 |
| 16 | 1630.0 | 55.0 | 98.0 | 93.0 |
| 17 | 135.0 | 782.0 | 857.0 | 102.0 |
| 18 | 199.25 | 633.25 | 382.25 | 661.25 |
| 19 | 578.0 | 276.0 | 718.0 | 304.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.189 | 0.271 | 0.37 | 0.17 |
| 02 | 0.402 | 0.201 | 0.294 | 0.102 |
| 03 | 0.456 | 0.122 | 0.119 | 0.303 |
| 04 | 0.714 | 0.066 | 0.069 | 0.151 |
| 05 | 0.187 | 0.219 | 0.381 | 0.214 |
| 06 | 0.011 | 0.739 | 0.039 | 0.211 |
| 07 | 0.006 | 0.004 | 0.99 | 0.001 |
| 08 | 0.991 | 0.003 | 0.005 | 0.001 |
| 09 | 0.962 | 0.001 | 0.001 | 0.036 |
| 10 | 0.999 | 0.0 | 0.0 | 0.001 |
| 11 | 0.006 | 0.3 | 0.689 | 0.005 |
| 12 | 0.008 | 0.551 | 0.023 | 0.418 |
| 13 | 0.025 | 0.003 | 0.97 | 0.002 |
| 14 | 0.887 | 0.035 | 0.051 | 0.027 |
| 15 | 0.825 | 0.027 | 0.021 | 0.128 |
| 16 | 0.869 | 0.029 | 0.052 | 0.05 |
| 17 | 0.072 | 0.417 | 0.457 | 0.054 |
| 18 | 0.106 | 0.338 | 0.204 | 0.352 |
| 19 | 0.308 | 0.147 | 0.383 | 0.162 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.279 | 0.079 | 0.391 | -0.382 |
| 02 | 0.475 | -0.215 | 0.161 | -0.887 |
| 03 | 0.599 | -0.713 | -0.739 | 0.193 |
| 04 | 1.046 | -1.319 | -1.28 | -0.499 |
| 05 | -0.291 | -0.134 | 0.42 | -0.156 |
| 06 | -3.024 | 1.082 | -1.839 | -0.171 |
| 07 | -3.599 | -3.97 | 1.373 | -5.095 |
| 08 | 1.375 | -4.225 | -3.679 | -5.095 |
| 09 | 1.345 | -5.095 | -4.798 | -1.908 |
| 10 | 1.382 | -5.521 | -5.521 | -4.798 |
| 11 | -3.524 | 0.18 | 1.012 | -3.767 |
| 12 | -3.328 | 0.788 | -2.351 | 0.512 |
| 13 | -2.265 | -4.225 | 1.353 | -4.382 |
| 14 | 1.263 | -1.937 | -1.571 | -2.206 |
| 15 | 1.191 | -2.206 | -2.444 | -0.666 |
| 16 | 1.243 | -2.114 | -1.551 | -1.602 |
| 17 | -1.235 | 0.51 | 0.601 | -1.511 |
| 18 | -0.851 | 0.299 | -0.204 | 0.342 |
| 19 | 0.208 | -0.527 | 0.424 | -0.431 |
| P-value | Threshold |
|---|---|
| 0.001 | 0.95816 |
| 0.0005 | 2.41186 |
| 0.0001 | 5.44456 |