IRF1.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	IRF1.H12CORE.0.P.B
Gene (human)	IRF1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Irf1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	19
Consensus	hWnnGAAASYGAAAShvvn
GC content	39.08%
Information content (bits; total / per base)	17.398 / 0.916
Data sources	ChIP-Seq
Aligned words	681

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	8 (46)	0.906	0.987	0.902	0.976	0.92	0.991	6.492	7.652	391.162	693.796
Mouse	15 (97)	0.967	0.994	0.949	0.988	0.981	0.997	6.735	7.581	460.357	747.745

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	IRF {3.5.3} (TFClass)
TF subfamily	{3.5.3.0} (TFClass)
TFClass ID	TFClass: 3.5.3.0.1
HGNC	HGNC:6116
MGI	MGI:96590
EntrezGene (human)	GeneID:3659 (SSTAR profile)
EntrezGene (mouse)	GeneID:16362 (SSTAR profile)
UniProt ID (human)	IRF1_HUMAN
UniProt ID (mouse)	IRF1_MOUSE
UniProt AC (human)	P10914 (TFClass)
UniProt AC (mouse)	P15314 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	8 human, 15 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	IRF1.H12CORE.0.P.B.pcm
PWM	IRF1.H12CORE.0.P.B.pwm
PFM	IRF1.H12CORE.0.P.B.pfm
Alignment	IRF1.H12CORE.0.P.B.words.tsv
Threshold to P-value map	IRF1.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	IRF1.H12CORE.0.P.B_jaspar_format.txt
MEME format	IRF1.H12CORE.0.P.B_meme_format.meme
Transfac format	IRF1.H12CORE.0.P.B_transfac_format.txt
Homer format	IRF1.H12CORE.0.P.B_homer_format_0.001.txt IRF1.H12CORE.0.P.B_homer_format_0.0005.txt IRF1.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	395.0	107.0	88.0	91.0
02	439.0	64.0	75.0	103.0
03	166.0	180.0	217.0	118.0
04	171.0	130.0	121.0	259.0
05	77.0	11.0	589.0	4.0
06	655.0	5.0	19.0	2.0
07	665.0	4.0	9.0	3.0
08	659.0	6.0	6.0	10.0
09	27.0	267.0	379.0	8.0
10	95.0	120.0	15.0	451.0
11	16.0	5.0	657.0	3.0
12	648.0	3.0	27.0	3.0
13	647.0	8.0	11.0	15.0
14	658.0	5.0	17.0	1.0
15	14.0	259.0	402.0	6.0
16	88.0	251.0	39.0	303.0
17	276.0	107.0	231.0	67.0
18	307.0	105.0	204.0	65.0
19	242.0	139.0	174.0	126.0

PFM

	A	C	G	T
01	0.58	0.157	0.129	0.134
02	0.645	0.094	0.11	0.151
03	0.244	0.264	0.319	0.173
04	0.251	0.191	0.178	0.38
05	0.113	0.016	0.865	0.006
06	0.962	0.007	0.028	0.003
07	0.977	0.006	0.013	0.004
08	0.968	0.009	0.009	0.015
09	0.04	0.392	0.557	0.012
10	0.14	0.176	0.022	0.662
11	0.023	0.007	0.965	0.004
12	0.952	0.004	0.04	0.004
13	0.95	0.012	0.016	0.022
14	0.966	0.007	0.025	0.001
15	0.021	0.38	0.59	0.009
16	0.129	0.369	0.057	0.445
17	0.405	0.157	0.339	0.098
18	0.451	0.154	0.3	0.095
19	0.355	0.204	0.256	0.185

PWM

	A	C	G	T
01	0.836	-0.459	-0.651	-0.618
02	0.941	-0.963	-0.808	-0.496
03	-0.025	0.055	0.241	-0.362
04	0.004	-0.267	-0.338	0.416
05	-0.782	-2.611	1.234	-3.419
06	1.34	-3.255	-2.12	-3.857
07	1.355	-3.419	-2.783	-3.614
08	1.346	-3.115	-3.115	-2.693
09	-1.792	0.447	0.795	-2.882
10	-0.576	-0.346	-2.336	0.968
11	-2.277	-3.255	1.343	-3.614
12	1.33	-3.614	-1.792	-3.614
13	1.328	-2.882	-2.611	-2.336
14	1.345	-3.255	-2.222	-4.179
15	-2.398	0.416	0.854	-3.115
16	-0.651	0.385	-1.442	0.572
17	0.479	-0.459	0.303	-0.918
18	0.585	-0.477	0.179	-0.948
19	0.349	-0.201	0.022	-0.298

Standard thresholds

P-value	Threshold
0.001	1.76756
0.0005	3.06576
0.0001	5.79511