| Motif | HXD8.H12RSNP.0.SM.D |
| Gene (human) | HOXD8 (GeneCards) |
| Gene synonyms (human) | HOX4E |
| Gene (mouse) | Hoxd8 |
| Gene synonyms (mouse) | Hox-4.3, Hoxd-8 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | HXD8.H12RSNP.0.SM.D |
| Gene (human) | HOXD8 (GeneCards) |
| Gene synonyms (human) | HOX4E |
| Gene (mouse) | Hoxd8 |
| Gene synonyms (mouse) | Hox-4.3, Hoxd-8 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 11 |
| Consensus | nvbTAATKRbn |
| GC content | 36.22% |
| Information content (bits; total / per base) | 10.053 / 0.914 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9480 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.874 | 0.826 | 0.82 | 0.776 | 0.752 | 0.72 |
| best | 0.941 | 0.906 | 0.908 | 0.867 | 0.84 | 0.804 | |
| Methyl HT-SELEX, 1 experiments | median | 0.807 | 0.746 | 0.731 | 0.685 | 0.665 | 0.636 |
| best | 0.807 | 0.746 | 0.731 | 0.685 | 0.665 | 0.636 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.941 | 0.906 | 0.908 | 0.867 | 0.84 | 0.804 |
| best | 0.941 | 0.906 | 0.908 | 0.867 | 0.84 | 0.804 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | HOX-related {3.1.1} (TFClass) |
| TF subfamily | HOX8 {3.1.1.7} (TFClass) |
| TFClass ID | TFClass: 3.1.1.7.3 |
| HGNC | HGNC:5139 |
| MGI | MGI:96209 |
| EntrezGene (human) | GeneID:3234 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:15437 (SSTAR profile) |
| UniProt ID (human) | HXD8_HUMAN |
| UniProt ID (mouse) | HXD8_MOUSE |
| UniProt AC (human) | P13378 (TFClass) |
| UniProt AC (mouse) | P23463 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | HXD8.H12RSNP.0.SM.D.pcm |
| PWM | HXD8.H12RSNP.0.SM.D.pwm |
| PFM | HXD8.H12RSNP.0.SM.D.pfm |
| Alignment | HXD8.H12RSNP.0.SM.D.words.tsv |
| Threshold to P-value map | HXD8.H12RSNP.0.SM.D.thr |
| Motif in other formats | |
| JASPAR format | HXD8.H12RSNP.0.SM.D_jaspar_format.txt |
| MEME format | HXD8.H12RSNP.0.SM.D_meme_format.meme |
| Transfac format | HXD8.H12RSNP.0.SM.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1934.0 | 3250.0 | 2021.0 | 2275.0 |
| 02 | 2442.5 | 2698.5 | 3338.5 | 1000.5 |
| 03 | 1221.0 | 1319.0 | 1838.0 | 5102.0 |
| 04 | 1.0 | 12.0 | 5.0 | 9462.0 |
| 05 | 9480.0 | 0.0 | 0.0 | 0.0 |
| 06 | 9480.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.0 | 68.0 | 0.0 | 9412.0 |
| 08 | 16.0 | 79.0 | 5843.0 | 3542.0 |
| 09 | 3286.0 | 333.0 | 5027.0 | 834.0 |
| 10 | 1070.75 | 4684.75 | 2217.75 | 1506.75 |
| 11 | 2102.0 | 2850.0 | 2188.0 | 2340.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.204 | 0.343 | 0.213 | 0.24 |
| 02 | 0.258 | 0.285 | 0.352 | 0.106 |
| 03 | 0.129 | 0.139 | 0.194 | 0.538 |
| 04 | 0.0 | 0.001 | 0.001 | 0.998 |
| 05 | 1.0 | 0.0 | 0.0 | 0.0 |
| 06 | 1.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.0 | 0.007 | 0.0 | 0.993 |
| 08 | 0.002 | 0.008 | 0.616 | 0.374 |
| 09 | 0.347 | 0.035 | 0.53 | 0.088 |
| 10 | 0.113 | 0.494 | 0.234 | 0.159 |
| 11 | 0.222 | 0.301 | 0.231 | 0.247 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.203 | 0.316 | -0.159 | -0.041 |
| 02 | 0.03 | 0.13 | 0.342 | -0.861 |
| 03 | -0.662 | -0.585 | -0.254 | 0.766 |
| 04 | -6.581 | -5.112 | -5.785 | 1.384 |
| 05 | 1.386 | -6.943 | -6.943 | -6.943 |
| 06 | 1.386 | -6.943 | -6.943 | -6.943 |
| 07 | -6.943 | -3.519 | -6.943 | 1.378 |
| 08 | -4.865 | -3.374 | 0.902 | 0.401 |
| 09 | 0.327 | -1.957 | 0.751 | -1.043 |
| 10 | -0.793 | 0.681 | -0.066 | -0.452 |
| 11 | -0.12 | 0.184 | -0.08 | -0.013 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.254265 |
| 0.0005 | 6.26254 |
| 0.0001 | 7.56377 |