MotifHXD8.H12CORE.0.SM.B
Gene (human)HOXD8
(GeneCards)
Gene synonyms (human)HOX4E
Gene (mouse)Hoxd8
Gene synonyms (mouse)Hox-4.3, Hoxd-8
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusnvbTAATKRbn
GC content36.22%
Information content (bits; total / per base)10.053 / 0.914
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9480

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.874 0.826 0.82 0.776 0.752 0.72
best 0.941 0.906 0.908 0.867 0.84 0.804
Methyl HT-SELEX, 1 experiments median 0.807 0.746 0.731 0.685 0.665 0.636
best 0.807 0.746 0.731 0.685 0.665 0.636
Non-Methyl HT-SELEX, 1 experiments median 0.941 0.906 0.908 0.867 0.84 0.804
best 0.941 0.906 0.908 0.867 0.84 0.804
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX8 {3.1.1.7} (TFClass)
TFClass IDTFClass: 3.1.1.7.3
HGNCHGNC:5139
MGIMGI:96209
EntrezGene (human)GeneID:3234
(SSTAR profile)
EntrezGene (mouse)GeneID:15437
(SSTAR profile)
UniProt ID (human)HXD8_HUMAN
UniProt ID (mouse)HXD8_MOUSE
UniProt AC (human)P13378
(TFClass)
UniProt AC (mouse)P23463
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
011934.03250.02021.02275.0
022442.52698.53338.51000.5
031221.01319.01838.05102.0
041.012.05.09462.0
059480.00.00.00.0
069480.00.00.00.0
070.068.00.09412.0
0816.079.05843.03542.0
093286.0333.05027.0834.0
101070.754684.752217.751506.75
112102.02850.02188.02340.0
PFM
ACGT
010.2040.3430.2130.24
020.2580.2850.3520.106
030.1290.1390.1940.538
040.00.0010.0010.998
051.00.00.00.0
061.00.00.00.0
070.00.0070.00.993
080.0020.0080.6160.374
090.3470.0350.530.088
100.1130.4940.2340.159
110.2220.3010.2310.247
PWM
ACGT
01-0.2030.316-0.159-0.041
020.030.130.342-0.861
03-0.662-0.585-0.2540.766
04-6.581-5.112-5.7851.384
051.386-6.943-6.943-6.943
061.386-6.943-6.943-6.943
07-6.943-3.519-6.9431.378
08-4.865-3.3740.9020.401
090.327-1.9570.751-1.043
10-0.7930.681-0.066-0.452
11-0.120.184-0.08-0.013
Standard thresholds
P-value Threshold
0.001 5.254265
0.0005 6.26254
0.0001 7.56377