MotifHXD4.H12CORE.0.SM.B
Gene (human)HOXD4
(GeneCards)
Gene synonyms (human)HOX4B
Gene (mouse)Hoxd4
Gene synonyms (mouse)Hox-4.2, Hoxd-4
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusnnvbTAATKRbn
GC content37.97%
Information content (bits; total / per base)10.367 / 0.864
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9383

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.95 0.919 0.928 0.89 0.852 0.828
best 0.97 0.952 0.938 0.913 0.881 0.845
Methyl HT-SELEX, 2 experiments median 0.888 0.85 0.813 0.785 0.739 0.724
best 0.947 0.913 0.926 0.886 0.872 0.835
Non-Methyl HT-SELEX, 2 experiments median 0.961 0.938 0.934 0.904 0.856 0.833
best 0.97 0.952 0.938 0.913 0.881 0.845
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX4 {3.1.1.4} (TFClass)
TFClass IDTFClass: 3.1.1.4.4
HGNCHGNC:5138
MGIMGI:96208
EntrezGene (human)GeneID:3233
(SSTAR profile)
EntrezGene (mouse)GeneID:15436
(SSTAR profile)
UniProt ID (human)HXD4_HUMAN
UniProt ID (mouse)HXD4_MOUSE
UniProt AC (human)P09016
(TFClass)
UniProt AC (mouse)P10628
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
012389.252151.252473.252369.25
021930.03726.02014.01713.0
032177.02471.04298.0437.0
04371.03692.01061.04259.0
052.04.01.09376.0
069383.00.00.00.0
079383.00.00.00.0
080.0870.00.08513.0
093.0136.06304.02940.0
106632.0171.02353.0227.0
111086.03433.01997.02867.0
121773.52747.52854.52007.5
PFM
ACGT
010.2550.2290.2640.253
020.2060.3970.2150.183
030.2320.2630.4580.047
040.040.3930.1130.454
050.00.00.00.999
061.00.00.00.0
071.00.00.00.0
080.00.0930.00.907
090.00.0140.6720.313
100.7070.0180.2510.024
110.1160.3660.2130.306
120.1890.2930.3040.214
PWM
ACGT
010.018-0.0860.0530.01
02-0.1950.462-0.152-0.314
03-0.0750.0520.605-1.676
04-1.8390.453-0.7920.596
05-6.306-5.923-6.5711.385
061.386-6.934-6.934-6.934
071.386-6.934-6.934-6.934
08-6.934-0.99-6.9341.288
09-6.096-2.8320.9880.226
101.039-2.6060.003-2.326
11-0.7690.381-0.1610.2
12-0.2790.1580.196-0.156
Standard thresholds
P-value Threshold
0.001 4.82506
0.0005 5.96312
0.0001 7.739225