MotifHXD3.H12CORE.0.SM.B
Gene (human)HOXD3
(GeneCards)
Gene synonyms (human)HOX1D, HOX4A
Gene (mouse)Hoxd3
Gene synonyms (mouse)Hox-4.1, Hoxd-3
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length13
ConsensusnbvCTAATTASvn
GC content40.58%
Information content (bits; total / per base)13.597 / 1.046
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8662

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.949 0.928 0.886 0.872 0.813 0.814
best 0.997 0.996 0.994 0.991 0.984 0.978
Methyl HT-SELEX, 1 experiments median 0.997 0.996 0.994 0.991 0.984 0.978
best 0.997 0.996 0.994 0.991 0.984 0.978
Non-Methyl HT-SELEX, 3 experiments median 0.902 0.864 0.781 0.759 0.65 0.662
best 0.995 0.993 0.99 0.985 0.976 0.967
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX3 {3.1.1.3} (TFClass)
TFClass IDTFClass: 3.1.1.3.3
HGNCHGNC:5137
MGIMGI:96207
EntrezGene (human)GeneID:3232
(SSTAR profile)
EntrezGene (mouse)GeneID:15434
(SSTAR profile)
UniProt ID (human)HXD3_HUMAN
UniProt ID (mouse)HXD3_MOUSE
UniProt AC (human)P31249
(TFClass)
UniProt AC (mouse)P09027
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012135.02016.02481.02030.0
02965.54866.51322.51507.5
032241.01943.04313.0165.0
0443.06967.0147.01505.0
050.00.00.08662.0
068662.00.00.00.0
078662.00.00.00.0
080.018.00.08644.0
090.06.01951.06705.0
107937.04.0709.012.0
11317.05432.02369.0544.0
121222.54176.52106.51156.5
131539.753257.751604.752259.75
PFM
ACGT
010.2460.2330.2860.234
020.1110.5620.1530.174
030.2590.2240.4980.019
040.0050.8040.0170.174
050.00.00.01.0
061.00.00.00.0
071.00.00.00.0
080.00.0020.00.998
090.00.0010.2250.774
100.9160.00.0820.001
110.0370.6270.2730.063
120.1410.4820.2430.134
130.1780.3760.1850.261
PWM
ACGT
01-0.014-0.0710.136-0.065
02-0.8060.809-0.492-0.362
030.034-0.1080.688-2.562
04-3.8691.168-2.676-0.363
05-6.863-6.863-6.8631.386
061.386-6.863-6.863-6.863
071.386-6.863-6.863-6.863
08-6.863-4.672-6.8631.383
09-6.863-5.569-0.1041.129
101.298-5.846-1.114-5.024
11-1.9150.9190.09-1.378
12-0.5710.656-0.028-0.626
13-0.3410.408-0.2990.043
Standard thresholds
P-value Threshold
0.001 1.609715
0.0005 3.47836
0.0001 7.194335