MotifHXD13.H12CORE.1.SM.B
Gene (human)HOXD13
(GeneCards)
Gene synonyms (human)HOX4I
Gene (mouse)Hoxd13
Gene synonyms (mouse)Hox-4.8
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length11
ConsensusndTTTACGASn
GC content38.95%
Information content (bits; total / per base)12.429 / 1.13
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8318

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (7) 0.851 0.862 0.708 0.747 0.81 0.821 2.341 2.429 74.018 82.553

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 5 experiments median 0.775 0.737 0.685 0.659 0.613 0.605
best 0.994 0.991 0.967 0.956 0.908 0.892
Methyl HT-SELEX, 1 experiments median 0.994 0.991 0.962 0.954 0.836 0.84
best 0.994 0.991 0.962 0.954 0.836 0.84
Non-Methyl HT-SELEX, 4 experiments median 0.748 0.719 0.659 0.639 0.596 0.589
best 0.99 0.985 0.967 0.956 0.908 0.892
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.17
HGNCHGNC:5136
MGIMGI:96205
EntrezGene (human)GeneID:3239
(SSTAR profile)
EntrezGene (mouse)GeneID:15433
(SSTAR profile)
UniProt ID (human)HXD13_HUMAN
UniProt ID (mouse)HXD13_MOUSE
UniProt AC (human)P35453
(TFClass)
UniProt AC (mouse)P70217
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 4
Methyl-HT-SELEX 1
PCM
ACGT
012048.751588.752738.751941.75
021433.0875.01923.04087.0
03248.047.0298.07725.0
0492.024.022.08180.0
05906.048.06.07358.0
068318.00.00.00.0
070.06632.01.01685.0
08249.010.07841.0218.0
097523.077.0658.060.0
10224.0993.06407.0694.0
111601.52691.52758.51266.5
PFM
ACGT
010.2460.1910.3290.233
020.1720.1050.2310.491
030.030.0060.0360.929
040.0110.0030.0030.983
050.1090.0060.0010.885
061.00.00.00.0
070.00.7970.00.203
080.030.0010.9430.026
090.9040.0090.0790.007
100.0270.1190.770.083
110.1930.3240.3320.152
PWM
ACGT
01-0.015-0.2690.275-0.068
02-0.372-0.864-0.0780.675
03-2.118-3.744-1.9361.312
04-3.095-4.373-4.4521.369
05-0.829-3.724-5.531.263
061.385-6.827-6.827-6.827
07-6.8271.159-6.46-0.21
08-2.114-5.1351.326-2.246
091.285-3.268-1.148-3.51
10-2.219-0.7381.125-1.095
11-0.2610.2580.282-0.495
Standard thresholds
P-value Threshold
0.001 3.679365
0.0005 4.85848
0.0001 7.264295