| Motif | HXD12.H12CORE.0.SM.B |
| Gene (human) | HOXD12 (GeneCards) |
| Gene synonyms (human) | HOX4H |
| Gene (mouse) | Hoxd12 |
| Gene synonyms (mouse) | Hox-4.7, Hoxd-12 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | HXD12.H12CORE.0.SM.B |
| Gene (human) | HOXD12 (GeneCards) |
| Gene synonyms (human) | HOX4H |
| Gene (mouse) | Hoxd12 |
| Gene synonyms (mouse) | Hox-4.7, Hoxd-12 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 11 |
| Consensus | nWTTACGAYbn |
| GC content | 38.62% |
| Information content (bits; total / per base) | 10.246 / 0.931 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 7191 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 5 experiments | median | 0.95 | 0.929 | 0.851 | 0.829 | 0.731 | 0.728 |
| best | 0.975 | 0.959 | 0.945 | 0.923 | 0.881 | 0.856 | |
| Methyl HT-SELEX, 1 experiments | median | 0.975 | 0.959 | 0.945 | 0.923 | 0.881 | 0.856 |
| best | 0.975 | 0.959 | 0.945 | 0.923 | 0.881 | 0.856 | |
| Non-Methyl HT-SELEX, 4 experiments | median | 0.91 | 0.881 | 0.807 | 0.782 | 0.7 | 0.693 |
| best | 0.965 | 0.943 | 0.93 | 0.902 | 0.858 | 0.831 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | HOX-related {3.1.1} (TFClass) |
| TF subfamily | HOX9-13 {3.1.1.8} (TFClass) |
| TFClass ID | TFClass: 3.1.1.8.13 |
| HGNC | HGNC:5135 |
| MGI | MGI:96204 |
| EntrezGene (human) | GeneID:3238 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:15432 (SSTAR profile) |
| UniProt ID (human) | HXD12_HUMAN |
| UniProt ID (mouse) | HXD12_MOUSE |
| UniProt AC (human) | P35452 (TFClass) |
| UniProt AC (mouse) | P23812 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 4 |
| Methyl-HT-SELEX | 1 |
| PCM | HXD12.H12CORE.0.SM.B.pcm |
| PWM | HXD12.H12CORE.0.SM.B.pwm |
| PFM | HXD12.H12CORE.0.SM.B.pfm |
| Alignment | HXD12.H12CORE.0.SM.B.words.tsv |
| Threshold to P-value map | HXD12.H12CORE.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | HXD12.H12CORE.0.SM.B_jaspar_format.txt |
| MEME format | HXD12.H12CORE.0.SM.B_meme_format.meme |
| Transfac format | HXD12.H12CORE.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2018.25 | 1437.25 | 1781.25 | 1954.25 |
| 02 | 967.5 | 257.5 | 629.5 | 5336.5 |
| 03 | 218.0 | 110.0 | 51.0 | 6812.0 |
| 04 | 2513.0 | 6.0 | 28.0 | 4644.0 |
| 05 | 7191.0 | 0.0 | 0.0 | 0.0 |
| 06 | 0.0 | 5613.0 | 0.0 | 1578.0 |
| 07 | 7.0 | 103.0 | 6387.0 | 694.0 |
| 08 | 6665.0 | 103.0 | 359.0 | 64.0 |
| 09 | 75.0 | 3505.0 | 1654.0 | 1957.0 |
| 10 | 879.25 | 2850.25 | 2222.25 | 1239.25 |
| 11 | 1761.5 | 1690.5 | 1764.5 | 1974.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.281 | 0.2 | 0.248 | 0.272 |
| 02 | 0.135 | 0.036 | 0.088 | 0.742 |
| 03 | 0.03 | 0.015 | 0.007 | 0.947 |
| 04 | 0.349 | 0.001 | 0.004 | 0.646 |
| 05 | 1.0 | 0.0 | 0.0 | 0.0 |
| 06 | 0.0 | 0.781 | 0.0 | 0.219 |
| 07 | 0.001 | 0.014 | 0.888 | 0.097 |
| 08 | 0.927 | 0.014 | 0.05 | 0.009 |
| 09 | 0.01 | 0.487 | 0.23 | 0.272 |
| 10 | 0.122 | 0.396 | 0.309 | 0.172 |
| 11 | 0.245 | 0.235 | 0.245 | 0.275 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.116 | -0.223 | -0.009 | 0.083 |
| 02 | -0.619 | -1.936 | -1.047 | 1.087 |
| 03 | -2.101 | -2.775 | -3.521 | 1.331 |
| 04 | 0.335 | -5.389 | -4.087 | 0.948 |
| 05 | 1.385 | -6.698 | -6.698 | -6.698 |
| 06 | -6.698 | 1.138 | -6.698 | -0.13 |
| 07 | -5.274 | -2.839 | 1.267 | -0.95 |
| 08 | 1.309 | -2.839 | -1.606 | -3.303 |
| 09 | -3.149 | 0.667 | -0.083 | 0.085 |
| 10 | -0.714 | 0.46 | 0.212 | -0.371 |
| 11 | -0.02 | -0.061 | -0.019 | 0.094 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.71237 |
| 0.0005 | 5.715255 |
| 0.0001 | 7.598885 |