MotifHXD12.H12CORE.0.SM.B
Gene (human)HOXD12
(GeneCards)
Gene synonyms (human)HOX4H
Gene (mouse)Hoxd12
Gene synonyms (mouse)Hox-4.7, Hoxd-12
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusnWTTACGAYbn
GC content38.62%
Information content (bits; total / per base)10.246 / 0.931
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7191

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 5 experiments median 0.95 0.929 0.851 0.829 0.731 0.728
best 0.975 0.959 0.945 0.923 0.881 0.856
Methyl HT-SELEX, 1 experiments median 0.975 0.959 0.945 0.923 0.881 0.856
best 0.975 0.959 0.945 0.923 0.881 0.856
Non-Methyl HT-SELEX, 4 experiments median 0.91 0.881 0.807 0.782 0.7 0.693
best 0.965 0.943 0.93 0.902 0.858 0.831
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.13
HGNCHGNC:5135
MGIMGI:96204
EntrezGene (human)GeneID:3238
(SSTAR profile)
EntrezGene (mouse)GeneID:15432
(SSTAR profile)
UniProt ID (human)HXD12_HUMAN
UniProt ID (mouse)HXD12_MOUSE
UniProt AC (human)P35452
(TFClass)
UniProt AC (mouse)P23812
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 1
PCM
ACGT
012018.251437.251781.251954.25
02967.5257.5629.55336.5
03218.0110.051.06812.0
042513.06.028.04644.0
057191.00.00.00.0
060.05613.00.01578.0
077.0103.06387.0694.0
086665.0103.0359.064.0
0975.03505.01654.01957.0
10879.252850.252222.251239.25
111761.51690.51764.51974.5
PFM
ACGT
010.2810.20.2480.272
020.1350.0360.0880.742
030.030.0150.0070.947
040.3490.0010.0040.646
051.00.00.00.0
060.00.7810.00.219
070.0010.0140.8880.097
080.9270.0140.050.009
090.010.4870.230.272
100.1220.3960.3090.172
110.2450.2350.2450.275
PWM
ACGT
010.116-0.223-0.0090.083
02-0.619-1.936-1.0471.087
03-2.101-2.775-3.5211.331
040.335-5.389-4.0870.948
051.385-6.698-6.698-6.698
06-6.6981.138-6.698-0.13
07-5.274-2.8391.267-0.95
081.309-2.839-1.606-3.303
09-3.1490.667-0.0830.085
10-0.7140.460.212-0.371
11-0.02-0.061-0.0190.094
Standard thresholds
P-value Threshold
0.001 4.71237
0.0005 5.715255
0.0001 7.598885