MotifHXD11.H12INVITRO.1.SM.B
Gene (human)HOXD11
(GeneCards)
Gene synonyms (human)HOX4F
Gene (mouse)Hoxd11
Gene synonyms (mouse)Hox-4.6, Hoxd-11
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length20
ConsensusnnndWhWhndTTTACGAYbn
GC content35.71%
Information content (bits; total / per base)13.471 / 0.674
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9808

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (7) 0.724 0.73 0.572 0.585 0.805 0.808 2.676 2.694 86.319 98.62

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.814 0.802 0.78 0.773 0.713 0.715
best 0.999 0.998 0.994 0.992 0.951 0.948
Methyl HT-SELEX, 1 experiments median 0.997 0.996 0.985 0.981 0.884 0.888
best 0.997 0.996 0.985 0.981 0.884 0.888
Non-Methyl HT-SELEX, 3 experiments median 0.631 0.608 0.575 0.565 0.542 0.541
best 0.999 0.998 0.994 0.992 0.951 0.948
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.11
HGNCHGNC:5134
MGIMGI:96203
EntrezGene (human)GeneID:3237
(SSTAR profile)
EntrezGene (mouse)GeneID:15431
(SSTAR profile)
UniProt ID (human)HXD11_HUMAN
UniProt ID (mouse)HXD11_MOUSE
UniProt AC (human)P31277
(TFClass)
UniProt AC (mouse)P23813
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012200.752887.752432.752286.75
022206.03591.01470.02541.0
032881.03337.01645.01945.0
043251.01057.02166.03334.0
052560.0765.0713.05770.0
065322.01001.0792.02693.0
076294.01321.0799.01394.0
085117.01800.01184.01707.0
093556.01831.01998.02423.0
101853.01301.01414.05240.0
11494.0110.0359.08845.0
12121.029.011.09647.0
132400.013.033.07362.0
149787.08.02.011.0
1518.07419.013.02358.0
1665.041.09407.0295.0
178678.0120.0780.0230.0
1892.05388.01921.02407.0
191578.04278.02185.01767.0
202118.752269.752153.753265.75
PFM
ACGT
010.2240.2940.2480.233
020.2250.3660.150.259
030.2940.340.1680.198
040.3310.1080.2210.34
050.2610.0780.0730.588
060.5430.1020.0810.275
070.6420.1350.0810.142
080.5220.1840.1210.174
090.3630.1870.2040.247
100.1890.1330.1440.534
110.050.0110.0370.902
120.0120.0030.0010.984
130.2450.0010.0030.751
140.9980.0010.00.001
150.0020.7560.0010.24
160.0070.0040.9590.03
170.8850.0120.080.023
180.0090.5490.1960.245
190.1610.4360.2230.18
200.2160.2310.220.333
PWM
ACGT
01-0.1080.163-0.008-0.07
02-0.1060.381-0.5110.036
030.1610.308-0.399-0.231
040.282-0.84-0.1240.307
050.043-1.163-1.2330.855
060.774-0.895-1.1280.094
070.942-0.618-1.119-0.564
080.735-0.309-0.727-0.362
090.371-0.292-0.205-0.012
10-0.28-0.633-0.550.759
11-1.598-3.084-1.9161.282
12-2.991-4.362-5.2181.369
13-0.021-5.078-4.2421.099
141.383-5.474-6.348-5.218
15-4.7951.107-5.078-0.039
16-3.596-4.0371.344-2.111
171.263-2.999-1.143-2.358
18-3.2590.787-0.244-0.019
19-0.440.556-0.115-0.327
20-0.146-0.077-0.130.286
Standard thresholds
P-value Threshold
0.001 3.35856
0.0005 4.56346
0.0001 6.99601