| Motif | HXD11.H12CORE.1.SM.B |
| Gene (human) | HOXD11 (GeneCards) |
| Gene synonyms (human) | HOX4F |
| Gene (mouse) | Hoxd11 |
| Gene synonyms (mouse) | Hox-4.6, Hoxd-11 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | HXD11.H12CORE.1.SM.B |
| Gene (human) | HOXD11 (GeneCards) |
| Gene synonyms (human) | HOX4F |
| Gene (mouse) | Hoxd11 |
| Gene synonyms (mouse) | Hox-4.6, Hoxd-11 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 20 |
| Consensus | nnndWhWhndTTTACGAYbn |
| GC content | 35.71% |
| Information content (bits; total / per base) | 13.471 / 0.674 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9808 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 1 (7) | 0.724 | 0.73 | 0.572 | 0.585 | 0.805 | 0.808 | 2.676 | 2.694 | 86.319 | 98.62 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.814 | 0.802 | 0.78 | 0.773 | 0.713 | 0.715 |
| best | 0.999 | 0.998 | 0.994 | 0.992 | 0.951 | 0.948 | |
| Methyl HT-SELEX, 1 experiments | median | 0.997 | 0.996 | 0.985 | 0.981 | 0.884 | 0.888 |
| best | 0.997 | 0.996 | 0.985 | 0.981 | 0.884 | 0.888 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.631 | 0.608 | 0.575 | 0.565 | 0.542 | 0.541 |
| best | 0.999 | 0.998 | 0.994 | 0.992 | 0.951 | 0.948 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | HOX-related {3.1.1} (TFClass) |
| TF subfamily | HOX9-13 {3.1.1.8} (TFClass) |
| TFClass ID | TFClass: 3.1.1.8.11 |
| HGNC | HGNC:5134 |
| MGI | MGI:96203 |
| EntrezGene (human) | GeneID:3237 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:15431 (SSTAR profile) |
| UniProt ID (human) | HXD11_HUMAN |
| UniProt ID (mouse) | HXD11_MOUSE |
| UniProt AC (human) | P31277 (TFClass) |
| UniProt AC (mouse) | P23813 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 1 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | HXD11.H12CORE.1.SM.B.pcm |
| PWM | HXD11.H12CORE.1.SM.B.pwm |
| PFM | HXD11.H12CORE.1.SM.B.pfm |
| Alignment | HXD11.H12CORE.1.SM.B.words.tsv |
| Threshold to P-value map | HXD11.H12CORE.1.SM.B.thr |
| Motif in other formats | |
| JASPAR format | HXD11.H12CORE.1.SM.B_jaspar_format.txt |
| MEME format | HXD11.H12CORE.1.SM.B_meme_format.meme |
| Transfac format | HXD11.H12CORE.1.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2200.75 | 2887.75 | 2432.75 | 2286.75 |
| 02 | 2206.0 | 3591.0 | 1470.0 | 2541.0 |
| 03 | 2881.0 | 3337.0 | 1645.0 | 1945.0 |
| 04 | 3251.0 | 1057.0 | 2166.0 | 3334.0 |
| 05 | 2560.0 | 765.0 | 713.0 | 5770.0 |
| 06 | 5322.0 | 1001.0 | 792.0 | 2693.0 |
| 07 | 6294.0 | 1321.0 | 799.0 | 1394.0 |
| 08 | 5117.0 | 1800.0 | 1184.0 | 1707.0 |
| 09 | 3556.0 | 1831.0 | 1998.0 | 2423.0 |
| 10 | 1853.0 | 1301.0 | 1414.0 | 5240.0 |
| 11 | 494.0 | 110.0 | 359.0 | 8845.0 |
| 12 | 121.0 | 29.0 | 11.0 | 9647.0 |
| 13 | 2400.0 | 13.0 | 33.0 | 7362.0 |
| 14 | 9787.0 | 8.0 | 2.0 | 11.0 |
| 15 | 18.0 | 7419.0 | 13.0 | 2358.0 |
| 16 | 65.0 | 41.0 | 9407.0 | 295.0 |
| 17 | 8678.0 | 120.0 | 780.0 | 230.0 |
| 18 | 92.0 | 5388.0 | 1921.0 | 2407.0 |
| 19 | 1578.0 | 4278.0 | 2185.0 | 1767.0 |
| 20 | 2118.75 | 2269.75 | 2153.75 | 3265.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.224 | 0.294 | 0.248 | 0.233 |
| 02 | 0.225 | 0.366 | 0.15 | 0.259 |
| 03 | 0.294 | 0.34 | 0.168 | 0.198 |
| 04 | 0.331 | 0.108 | 0.221 | 0.34 |
| 05 | 0.261 | 0.078 | 0.073 | 0.588 |
| 06 | 0.543 | 0.102 | 0.081 | 0.275 |
| 07 | 0.642 | 0.135 | 0.081 | 0.142 |
| 08 | 0.522 | 0.184 | 0.121 | 0.174 |
| 09 | 0.363 | 0.187 | 0.204 | 0.247 |
| 10 | 0.189 | 0.133 | 0.144 | 0.534 |
| 11 | 0.05 | 0.011 | 0.037 | 0.902 |
| 12 | 0.012 | 0.003 | 0.001 | 0.984 |
| 13 | 0.245 | 0.001 | 0.003 | 0.751 |
| 14 | 0.998 | 0.001 | 0.0 | 0.001 |
| 15 | 0.002 | 0.756 | 0.001 | 0.24 |
| 16 | 0.007 | 0.004 | 0.959 | 0.03 |
| 17 | 0.885 | 0.012 | 0.08 | 0.023 |
| 18 | 0.009 | 0.549 | 0.196 | 0.245 |
| 19 | 0.161 | 0.436 | 0.223 | 0.18 |
| 20 | 0.216 | 0.231 | 0.22 | 0.333 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.108 | 0.163 | -0.008 | -0.07 |
| 02 | -0.106 | 0.381 | -0.511 | 0.036 |
| 03 | 0.161 | 0.308 | -0.399 | -0.231 |
| 04 | 0.282 | -0.84 | -0.124 | 0.307 |
| 05 | 0.043 | -1.163 | -1.233 | 0.855 |
| 06 | 0.774 | -0.895 | -1.128 | 0.094 |
| 07 | 0.942 | -0.618 | -1.119 | -0.564 |
| 08 | 0.735 | -0.309 | -0.727 | -0.362 |
| 09 | 0.371 | -0.292 | -0.205 | -0.012 |
| 10 | -0.28 | -0.633 | -0.55 | 0.759 |
| 11 | -1.598 | -3.084 | -1.916 | 1.282 |
| 12 | -2.991 | -4.362 | -5.218 | 1.369 |
| 13 | -0.021 | -5.078 | -4.242 | 1.099 |
| 14 | 1.383 | -5.474 | -6.348 | -5.218 |
| 15 | -4.795 | 1.107 | -5.078 | -0.039 |
| 16 | -3.596 | -4.037 | 1.344 | -2.111 |
| 17 | 1.263 | -2.999 | -1.143 | -2.358 |
| 18 | -3.259 | 0.787 | -0.244 | -0.019 |
| 19 | -0.44 | 0.556 | -0.115 | -0.327 |
| 20 | -0.146 | -0.077 | -0.13 | 0.286 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.35856 |
| 0.0005 | 4.56346 |
| 0.0001 | 6.99601 |