MotifHXD10.H12CORE.0.SM.B
Gene (human)HOXD10
(GeneCards)
Gene synonyms (human)HOX4D, HOX4E
Gene (mouse)Hoxd10
Gene synonyms (mouse)Hox-4.5, Hoxd-10
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusndTTTACGAYbn
GC content38.13%
Information content (bits; total / per base)11.386 / 0.949
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8067

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.909 0.893 0.838 0.827 0.775 0.77
best 0.997 0.994 0.989 0.984 0.946 0.936
Methyl HT-SELEX, 2 experiments median 0.851 0.848 0.8 0.799 0.755 0.753
best 0.997 0.994 0.989 0.984 0.946 0.936
Non-Methyl HT-SELEX, 2 experiments median 0.909 0.893 0.838 0.827 0.775 0.77
best 0.986 0.975 0.975 0.962 0.938 0.919
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.8
HGNCHGNC:5133
MGIMGI:96202
EntrezGene (human)GeneID:3236
(SSTAR profile)
EntrezGene (mouse)GeneID:15430
(SSTAR profile)
UniProt ID (human)HXD10_HUMAN
UniProt ID (mouse)HXD10_MOUSE
UniProt AC (human)P28358
(TFClass)
UniProt AC (mouse)P28359
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
011848.252434.252294.251490.25
021910.51078.51770.53307.5
03322.082.0326.07337.0
0419.05.04.08039.0
052599.03.02.05463.0
068067.00.00.00.0
071.05247.02.02817.0
081.015.07437.0614.0
097064.070.0831.0102.0
1081.04571.01167.02248.0
111145.253795.251954.251172.25
121725.52049.51772.52519.5
PFM
ACGT
010.2290.3020.2840.185
020.2370.1340.2190.41
030.040.010.040.91
040.0020.0010.00.997
050.3220.00.00.677
061.00.00.00.0
070.00.650.00.349
080.00.0020.9220.076
090.8760.0090.1030.013
100.010.5670.1450.279
110.1420.470.2420.145
120.2140.2540.220.312
PWM
ACGT
01-0.0870.1880.129-0.302
02-0.054-0.625-0.130.494
03-1.829-3.177-1.8171.291
04-4.554-5.63-5.7781.382
050.253-5.952-6.1640.996
061.385-6.8-6.8-6.8
07-6.4320.955-6.1640.334
08-6.432-4.7631.304-1.187
091.253-3.33-0.885-2.964
10-3.1890.818-0.5460.108
11-0.5650.632-0.031-0.542
12-0.1560.016-0.1290.222
Standard thresholds
P-value Threshold
0.001 4.13546
0.0005 5.338525
0.0001 7.71787