MotifHXC8.H12CORE.0.SM.B
Gene (human)HOXC8
(GeneCards)
Gene synonyms (human)HOX3A
Gene (mouse)Hoxc8
Gene synonyms (mouse)Hox-3.1, Hoxc-8
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length13
ConsensusnhvYTAATGRSbn
GC content39.58%
Information content (bits; total / per base)10.667 / 0.821
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9037

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.967 0.945 0.949 0.921 0.9 0.872
best 0.968 0.947 0.952 0.924 0.917 0.886
Methyl HT-SELEX, 1 experiments median 0.966 0.944 0.947 0.918 0.882 0.857
best 0.966 0.944 0.947 0.918 0.882 0.857
Non-Methyl HT-SELEX, 1 experiments median 0.968 0.947 0.952 0.924 0.917 0.886
best 0.968 0.947 0.952 0.924 0.917 0.886
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX8 {3.1.1.7} (TFClass)
TFClass IDTFClass: 3.1.1.7.2
HGNCHGNC:5129
MGIMGI:96198
EntrezGene (human)GeneID:3224
(SSTAR profile)
EntrezGene (mouse)GeneID:15426
(SSTAR profile)
UniProt ID (human)HXC8_HUMAN
UniProt ID (mouse)HXC8_MOUSE
UniProt AC (human)P31273
(TFClass)
UniProt AC (mouse)P09025
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
012062.752473.752267.752232.75
021827.754214.751328.751665.75
032818.02667.02739.0813.0
041070.01267.0879.05821.0
0510.02.00.09025.0
069037.00.00.00.0
079037.00.00.00.0
081.02266.00.06770.0
0933.08.05743.03253.0
105991.024.02903.0119.0
11289.05826.01751.01171.0
121424.03712.02323.01578.0
132416.52348.51757.52514.5
PFM
ACGT
010.2280.2740.2510.247
020.2020.4660.1470.184
030.3120.2950.3030.09
040.1180.140.0970.644
050.0010.00.00.999
061.00.00.00.0
071.00.00.00.0
080.00.2510.00.749
090.0040.0010.6350.36
100.6630.0030.3210.013
110.0320.6450.1940.13
120.1580.4110.2570.175
130.2670.260.1940.278
PWM
ACGT
01-0.0910.0910.004-0.012
02-0.2120.623-0.53-0.304
030.2210.1660.192-1.02
04-0.746-0.578-0.9420.946
05-5.216-6.27-6.9011.384
061.386-6.901-6.901-6.901
071.386-6.901-6.901-6.901
08-6.5370.003-6.9011.097
09-4.161-5.3940.9320.364
100.975-4.4550.25-2.926
11-2.050.947-0.255-0.656
12-0.4610.4960.028-0.358
130.0670.039-0.2510.107
Standard thresholds
P-value Threshold
0.001 4.81931
0.0005 5.95836
0.0001 7.62086